Analysis of deviant behaviors and family functions in the population at risk of internet addiction among primary and secondary school students in Chengdu city, Sichuan province of China.

Background: This study explores the correlation between internet addiction (IA) and deviant behaviors among primary and secondary school students. It analyzes the impact of family functional factors, such as family relationships, parent-child communication, and parental control, on IA. The findings aim to provide a scientific basis for educators and parents to develop targeted preventive and intervention measures.

Intermolecular sulfur atom transfer cascade enabled late-stage introduction of sulfilimines into peptides.

Sulfilimines, a privileged class of -S(iv)[double bond, length as m-dash]N- functional groups found in nature, have been exploited as valuable building blocks in organic synthesis and as pharmacophores in drug discovery, and have aroused significant interest in the chemical community. Nevertheless, strategies for late-stage introduction of sulfilimines into peptides and proteins have still met with limited success. Herein, we have developed a method of introducing biological sulfilimine fragments into peptides by an intermolecular sulfur atom transfer cascade reaction, utilizing hydroxylamine condensed with the acid moieties of peptides and varied diaryl disulfides.

Organizational support enhances nurses' work-family enrichment: a person-context interactionist perspective.

Introduction: Attaining a favorable work-life balance is a complex and ongoing challenge in the nursing profession. According to a person-context interactionist perspective and the two-factor theory, this study investigated the underlying mechanism by which organizational support impacts work-family enrichment via protective factors (i.e.

The relationship between family function and the incidence of overweight/obesity in children and adolescents in Chengdu city, Sichuan province of China: based on latent profile analysis.

Background: Overweight/obesity in children and adolescents has become a global health problem, and family function may be associated with its occurrence. Studies exploring the association between family function and overweight/obesity in children and adolescents were performed in Western and Taiwan, China. To date, related studies haven't been conducted in Mainland China.

Performance, comparison and utilization of reduced sulfur (-2) compounds (S, FeS and SCN) in autotrophic denitrification process by thiosulfate-driven autotrophic denitrifier.

The coexistence of reduced sulfur (-2) compounds (S, FeS and SCN) are found in some industrial wastewaters due to pre-treatment of Fe(II) salts. These compounds as electron donors have attracted increasing interest in autotrophic denitrification process. However, the difference of their functions still remain unknown, which limit efficient utilization in autotrophic denitrification process.

The efficient utilization of thiocyanate on simultaneous removal of ammonium and nitrate through thiosulfate-driven autotrophic denitrifiers and anammox.

The efficient utilization of thiocyanate remain be an important bottleneck in the low-cost nitrogen removal for wastewaters containing thiocyanate. The study aimed to investigate the feasibility of thiocyanate in removal of nitrate and ammonium through anammox (AN) and thiosulfate-driven autotrophic denitrifiers (TSAD). The results showed that removal of nitrate and ammonium were achieved rapidly utilizing thiocyanate, which was attributed to degradation of thiocyanate by TSAD and cooperation with AN.

Adsorption mechanism of trace heavy metals on microplastics and simulating their effect on microalgae in river.

Microplastics (MPs) and heavy-metal contamination in freshwater is an increasing concern. Fe, Mn, Pb, Zn, Cr, and Cd are common heavy metals that can easily flow into rivers causing water pollution. Microplastics act as carriers for heavy metals and increase the transport of contaminants in freshwater systems.

Microbial compositions, ecological networks, and metabolomics in sediments of black-odour water in Dongguan, China.

Black-odour water with organic compounds and heavy metals caused by domestic and industrial activities has aroused people's attention in recent years, yet little is known about the ecological effects on aquatic organisms, especially microorganisms in sediments. To explore the response of microbial communities to environmental factors, the community and metabolites of nine river sediments with different pollution in Dongguan city, China were investigated using 16S rRNA gene sequencing and liquid chromatography tandem-mass. The results revealed that the composition and structure of sedimentary microbial communities significantly changed in rivers with varying pollution levels.

Distribution and Potential Sources of OCPs and PAHs in Waters from the Danshui River Basin in Yichang, China.

To investigate the concentrations, spatial distribution, potential sources and mass fluxes of organochlorine pesticides (OCPs) and polycyclic aromatic hydrocarbons (PAHs) in waters from the Danshui River Basin, a total of 20 water samples were collected and analyzed from a karstic river in Western Hubei of Central China. The average concentrations of total OCPs and PAHs in the river water were 4719 pg·L and 26.2 ng·L, respectively.

Readiness for hospital discharge in primary caregivers for children with acute lymphoblastic leukaemia.

Aim: To investigate existing status and factors affecting the readiness for hospital discharge in primary caregivers for children with acute lymphoblastic leukaemia in China.

Background: Acute lymphoblastic leukaemia is the most common childhood cancer, but there is not enough research on the readiness for hospital discharge.

Design: A cross-sectional study was performed by convenience sampling and questionnaire survey.

A randomized interventional study to promote milk secretion during mother-baby separation based on the health belief model: A consort compliant.

Background: Breast milk is the most important nutrition for premature babies, but mothers of premature infants have difficulty in initiating and sustaining lactation. Breastfeeding infants who are separated with mothers have decreased morbidity. Nevertheless, such decrease is limited due to insufficient milk supply resulting from mother-baby separation during lac.

Risk factors for episiotomy during vaginal childbirth: A retrospective cohort study in Western China.

Objective: To assess the incidence rates and risk factors for episiotomy during vaginal childbirth in a Western China context.

Methods: A retrospective hospital-based cohort study was conducted using computerized data of 3721 singleton vaginal deliveries after 28 weeks of gestation. Women who underwent episiotomy were compared with those who did not.

The association between obstructive sleep apnea and shortened telomere length: a systematic review and meta-analysis.

Objective: We aimed to provide a more precise estimate of the relationship between telomere length and obstructive sleep apnea (OSA) by systematically reviewing evidence.

Method: We conducted a systematic electronic search in the databases of the PUBMED, PsycINFO, OVID (Medline), EMBASE and other resources (such as Google Scholar). The methodological quality of the articles was assessed according to the Newcastle Ottawa Scale.

Comparability of the Patient-Reported Outcomes Measurement Information System Pediatric short form symptom measures across culture: examination between Chinese and American children with cancer.

Purpose: Patient-Reported Outcomes Measurement Information System (PROMIS) Pediatric forms measure symptoms and function of pediatric patients experiencing chronic disease by using the same measures. Comparability is one of the most important purposes of the PROMIS initiative. This study aimed to test the factorial structures of four symptom measures (i.

Pretreatment with pPolyHb attenuates H2O2-induced endothelial cell injury through inhibition of JNK/p38 MAPK pathway by upregulation of heme oxygenase-1.

Polymerized porcine hemoglobin (pPolyHb) exhibits a protective effect on ischemia/reperfusion of organ grafts. A series of experiments were performed to explore the underlying cytoprotective mechanisms of pPolyHb pretreatment on H2O2-induced cell death and apoptosis. The results showed that the pretreatment augmented heme oxygenase-1 (HO-1) expression, and at the same time, decreased the phosphorylation of JNK/p38 mitogen-activated protein kinase (MAPK) and intracellular ROS generation in H2O2-treated HUVECs.

The emotional distress of children with cancer in China: an item response analysis of C-Ped-PROMIS Anxiety and Depression short forms.

Purpose: The pediatric patient-reported outcomes measurement information system (PROMIS) was developed to provide self-reported item banks and short forms for children and adolescents (aged 8-17 years) experiencing a chronic illness to assess their quality of life and symptoms. The pediatric PROMIS short forms have been translated into Chinese and applied in children with cancer in China. This study aimed to describe psychometric properties of the Anxiety and Depression measures.

Crystallization and preliminary X-ray study of a (2R,3R)-2,3-butanediol dehydrogenase from Bacillus coagulans 2-6.

(2R,3R)-2,3-Butanediol dehydrogenase (R,R-BDH) from Bacillus coagulans 2-6 is a zinc-dependent medium-chain alcohol dehydrogenase. Recombinant R,R-BDH with a His6 tag at the C-terminus was expressed in Escherichia coli BL21 (DE3) cells and purified by Ni2+-chelating affinity and size-exclusion chromatography. Crystals were grown by the hanging-drop vapour-diffusion method at 289 K.

[Correlation study between OPN, CD44v6, MMP-9 and distant metastasis in laryngeal squamous cell carcinoma].

Objective: To investigate the expression and clinical significance of OPN, CD44v6 and MMP-9 in laryngeal squamous cell carcinomas (LSCC).

Method: The expression of OPN, CD44v6 and MMP-9 in the 47 cases of LSCC and 10 cases normal mucosa were detected by immunohistochemical method. The correlation between OPN, CD44v6 and MMP-9 proteins expressions and the correlation between them and clinicopathological feature were also studied.

Paraventricular nucleus corticotrophin releasing hormone contributes to sympathoexcitation via interaction with neurotransmitters in heart failure.

Recent studies indicate that systemic administration of tumor necrosis factor (TNF)-α induces increases in corticotrophin releasing hormone (CRH) and CRH type 1 receptors in the hypothalamic paraventricular nucleus (PVN). In this study, we explored the hypothesis that CRH in the PVN contributes to sympathoexcitation via interaction with neurotransmitters in heart failure (HF). Sprague-Dawley rats with HF or sham-operated controls (SHAM) were treated for 4 weeks with a continuous bilateral PVN infusion of the selective CRH-R1 antagonist NBI-27914 or vehicle.

TNF-α in hypothalamic paraventricular nucleus contributes to sympathoexcitation in heart failure by modulating AT1 receptor and neurotransmitters.

Proinflammatory cytokines, including tumor necrosis factor (TNF)-α, augment the progression of heart failure (HF) that is characterized by sympathoexcitation. In this study, we explored the role of TNF-α in hypothalamic paraventricular nucleus (PVN) in the exaggerated sympathetic activity observed in HF. Heart failure rats were made by ligating the left anterior descending coronary artery.