Cardiac function evaluation in children with spinal muscular atrophy: A case-control study.

Background: Spinal muscular atrophy (SMA) is an autosomal recessive disorder characterized by degeneration of lower motor neurons, resulting in progressive muscle weakness and atrophy. However, little is known regarding the cardiac function of children with SMA.

Methods: We recruited SMA patients younger than 18 years of age from January 1, 2022, to April 1, 2022, in the First Affiliated Hospital of Sun Yat-sen University.

Causal links between sedentary behavior, physical activity, and psychiatric disorders: a Mendelian randomization study.

Background: Studies suggest a correlation between excessive sedentary behavior, insufficient physical activity, and an elevated likelihood of experiencing psychiatric disorder. Nonetheless, the precise influence of sedentary behavior and physical activity on psychiatric disorder remains uncertain. Hence, the objective of this research was to investigate the possible causal relationship between sedentary behavior, physical activity, and the susceptibility to psychiatric disorder (depression, schizophrenia and bipolar disorder), utilizing a two-sample Mendelian randomization (MR) approach.

Exploration of Protective Factors Affecting Postoperative Natural Pregnancy in Patients with Endometriosis.

Objective: This study aimed to analyze the factors affecting natural pregnancy in patients with endometriosis (EMs) and to identify corresponding nursing measures. Understanding these factors is crucial as it may offer insights into improving fertility outcomes and enhancing the overall well-being of individuals with EMs. By identifying effective nursing measures, we hope to contribute to the development of targeted interventions that can positively impact the reproductive health of these patients.

The expression of Runx2 in the pathogenesis of periodontitis.

Objective: Runt-related transcription factor 2 (Runx2) plays an important role in bone metabolism; however, the relationship between Runx2 and periodontitis remains unclear. We investigated Runx2 expression in the gingiva of patients to explore its role in periodontitis.

Methods: Gingival samples of patients were collected, including healthy samples (control group) and periodontitis samples (P group).

Identification of Hub Biomarkers and Immune and Inflammation Pathways Contributing to Kawasaki Disease Progression with RT-qPCR Verification.

Background: Kawasaki disease (KD) is characterized by a disordered inflammation response of unknown etiology. Immune cells are closely associated with its onset, although the immune-related genes' expression and possibly involved immune regulatory mechanisms are little known. This study aims to identify KD-implicated significant immune- and inflammation-related biomarkers and pathways and their association with immune cell infiltration.

Stent implantation in severe aortic coarctation in a pediatric patient with Turner syndrome: Case report and literature review.

Background: Turner syndrome is a rare systemic disease and a significant proportion of these patients experience aortic coarctation. Selection of optimal therapy for aortic coarctation in patients with Turner syndrome is difficult due to the pathologic change of the systemic vessel.

Case Presentation: We report one successful case of covered stent implantation for the treatment of severe native coarctation of the aorta in a 15-year-old patient with Turner syndrome weighing 36 kg.

Haploinsufficiency of A20 in a Chinese child caused by loss-of-function mutations in TNFAIP3: A case report and review of the literature.

Case Presentation: A 3-year-and-6-month-old child was reported to have recurrent high fever with generalized lymph node enlargement and significant elevation of inflammatory markers such as C-reactive protein and procalcitonin in tests. Later, whole exome sequencing determined that the child's disease was haploinsufficiency of A20 (HA20).

Results: After immunosuppressive therapy, the child's symptoms improved significantly, and the inflammatory markers dropped to the normal range.

Effect of Targeted Care plus Exercise Intervention on Blood Glucose Levels and Maternal and Newborn Outcomes in Patients with Gestational Diabetes Mellitus.

Objective: To evaluate the effect of targeted care plus exercise intervention on blood glucose levels and maternal and newborn outcomes in patients with gestational diabetes mellitus (GDM).

Methods: A total of 96 patients with GDM admitted to our hospital between March 2018 and January 2020 were recruited and assigned to receive either routine nursing (routine group) or targeted care plus exercise intervention (study group) via random method, with 48 patients in each group. Outcome measures included blood glucose, immune function, maternal and newborn outcome, and nursing satisfaction.

Predictors for Intravenous Immunoglobulin Resistance in Patients with Kawasaki Disease.

Background: Between 10 and 20% of Kawasaki disease (KD) patients are resistant to treatment with initial intravenous immunoglobulin (IVIG) and have a high risk of developing coronary artery lesions. Some studies have been conducted to identify predictive factors. However, the results are controversial.

Duchenne Muscular Dystrophy With Low Acidic α-Glucosidase Activity: Two Case Reports and Literature Review.

Background: Pompe disease is usually considered in children with elevated creatine kinase (CK) levels and decreased acidic α-glucosidase (GAA) enzyme activity. However, there are exceptions, such as GAA pseudo deficiency alleles, which result in lower GAA enzyme activity but do not cause Pompe disease. Here, we report two cases presenting with high CK levels and low GAA activity who were ultimately diagnosed with Duchenne muscular dystrophy (DMD).

Copper Oxide-Based Photocatalysts and Photocathodes: Fundamentals and Recent Advances.

This work aims at reviewing the most impactful results obtained on the development of Cu-based photocathodes. The need of a sustainable exploitation of renewable energy sources and the parallel request of reducing pollutant emissions in airborne streams and in waters call for new technologies based on the use of efficient, abundant, low-toxicity and low-cost materials. Photoelectrochemical devices that adopts abundant element-based photoelectrodes might respond to these requests being an enabling technology for the direct use of sunlight to the production of energy fuels form water electrolysis (H) and CO reduction (to alcohols, light hydrocarbons), as well as for the degradation of pollutants.

A Retrospective Cohort Study of Intravenous Immunoglobulin Therapy in the Acute Phase of Kawasaki Disease: The Earlier, the Better?

Background: Although intravenous immunoglobulin (IVIG) is expected to prevent coronary artery abnormalities of Kawasaki disease (KD) in the acute phase, the timing and effectiveness of IVIG remain to be determined. The association of timing of IVIG administration in KD patients with coronary artery abnormalities is evaluated in this cohort study.

Methods: We systematically studied KD patients from two participating institutions between 2015 and 2017.

Case Report: Infection in a Chinese Child With a Complex Heterozygous Mutation.

(TM) infection is rarely seen in clinical practice, and its pathogenesis may be related to deficiency in antifungal immune function. Human caspase recruitment domain-containing protein 9 (CARD9) is a key molecule in fungal immune surveillance. There have been no previous case reports of TM infection in individuals with gene mutations.

Sitosterolemia With Atherosclerosis in a Child: A Case Report.

Sitosterolemia is a rare condition in children and is often misdiagnosed as familial hypercholesterolemia. Serious complications can result if not treated promptly and effectively. When pediatric patients are diagnosed with sitosterolemia, vascular, and cardiac studies are important to evaluate for the presence of atherosclerosis.

Synthesis and characterization of Ni-doped anatase TiO loaded on magnetic activated carbon for rapidly removing triphenylmethane dyes.

In this work, we employed the in situ synthesis method to implant FeO into activated carbon (AC), in which the synthesis of the magnetic AC (MAC) was realized. Thence, Ni-doped anatase TiO (NATiO) were anchored on different addition amount of MAC to synthesize the series of Ni-TiO/MAC photocatalysts. The chemical compositions and physical properties of these nanocomposites were analyzed by various characterization technologies.

Expression and methylation of Dickkopf-1 in the pathogenesis and malignant transformation of oral submucous fibrosis.

Background: Dickkopf-1 is an inhibitor of the Wnt/β-catenin pathway, but the role of Dickkopf-1 in oral submucous fibrosis remains unclear. We evaluated the protein expression and gene methylation levels of dickkopf-1 to determine the mechanism underlying abnormal Wnt/β-catenin pathway activation.

Methods: Healthy mucosa, oral submucous fibrosis, oral squamous cell carcinoma, and cancer-adjacent tissues were collected.

[Hereditary gingival fibromatosis: a three-generation case report].

Hereditary gingival fibromatosis (HGF) is a familial hereditary disease; while it is rare and usually benign, it is also characterized by the slow and progressive development of gingival tissue. This paper reports on the clinical examina-tion and history of HGF in a family of patients.

Surfactants-assisted preparation of BiVO with novel morphologies via microwave method and CdS decoration for enhanced photocatalytic properties.

The development of a highly efficient and rapid method for the accurate preparation of photocatalysts with novel morphologies is a hot research topic. The different morphologies of BiVO was prepared using surfactants-assisted microwave method, and demonstrated irregular (no surfactant), octahedral (sodium dodecyl benzene sulfonate), olive-like (polyvinylpyrrolidone) and hollow structures (ethylenediaminetetraacetic acid), respectively. The BiVO-CdS were synthesized using the chemical-bath-deposition method with different morphologies of BiVO as the substrates.

Land use-induced change in trophic state of Shenzhen Bay (South China) over the past half-century.

Mangroves connect terrestrial and marine ecosystems and are sensitive to environmental change, and the sediments within faithfully record long-term changes in the aquatic environment and supplement the generally short monitoring archives. Here we present a sediment-core record of TN, TP, TOC, and C/N ratios from the Futian mangrove wetland, Shenzhen Bay (South China), and compare with our remote sensing-derived land use change and the nearby seawater monitoring records. Our reconstructed record extends the history of tropic state change back to the Year 1958, supplementing the monitoring activity initiated in 1987.

Hierarchical fabrication Z-scheme photocatalyst of BiVO (0 4 0)-Ag@CdS for enhanced photocatalytic properties under simulated sunlight irradiation.

Interfacial charge separation and heterojunction system are conductive to improving its photocatalytic performance. Herein, we designed a novel photocatalyst of Z-scheme BiVO (0 4 0)-Ag@CdS, in which Ag was photo-deposition on the (0 4 0) facets of BiVO as the "linker" between BiVO and CdS. Characterizations of XRD and SEM clearly revealed that the BiVO (0 4 0)-Ag@CdS was prepared through hierarchical fabrication.

Constructing a Z-scheme Heterojunction of Egg-Like Core@shell CdS@TiO₂ Photocatalyst via a Facile Reflux Method for Enhanced Photocatalytic Performance.

A well designed and accurate method of control of different shell thickness and electronic transmission in a Z-scheme core@shell system is conducive to obtaining an optimum photocatalytic performance. Herein, the Z-scheme heterojunction of egg-like core@shell CdS@TiO₂photocatalysts with controlled shell thickness (13 nm, 15 nm, 17 nm, 22 nm) were synthesized by a facile reflux method, and the CdS@TiO₂ structure was proved by a series of characterizations. The photodegradation ratio on methylene blue and tetracycline hydrochloride over the 0.

Fabrication of interlayer β-CD/g-CN@MoS for highly enhanced photodegradation of glyphosate under simulated sunlight irradiation.

Graphitic carbon nitride (g-CN) has been considered to be a promising metal-free photocatalyst, although the high recombination rate of charge carriers and poor absorption of visible light have limited its applications. In order to overcome these problems, an interlayer composite photocatalyst that comprised β-cyclodextrin (β-CD), oxygen-doped CN (O-CN) and molybdenum disulfide (MoS) was successfully constructed for the highly enhanced photodegradation of glyphosate in this study. The structure and morphology, optical properties, and photoelectrochemical properties of the prepared photocatalyst were characterized a series of characterization techniques.