Publications by authors named "Xiufang Duan"

Article Synopsis
  • The study investigates the effectiveness of renal fractional flow reserve (rFFR) in identifying significant renal artery stenosis (RAS) by comparing it with color Doppler ultrasonography (CDU) and angiography.
  • It includes data from 77 renal artery lesions in 58 patients, measuring rFFR through a pressure wire after inducing renal hyperemia and gathering various ultrasound parameters.
  • Results show strong correlations between rFFR and CDU measurements, with specific cut-off points identified for parameters such as peak systolic velocity (PSV) and renal-to-aortic ratio (RAR) to effectively predict significant RAS.
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Aim: To make a bibliometric analysis on post-traumatic growth (PTG) after childbirth.

Methods: The topic advanced search strategy extracted the information from the Web of Science Core Collection. Descriptive statistics were performed using Excel, and bibliometric analysis was performed using VOSviewer.

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Article Synopsis
  • Hyperechoic crystal deposits in the kidney medulla can be observed in CKD patients using ultrasonography, and their presence is linked to hyperuricemia and ischemic nephropathy.
  • A study involving 515 CKD patients found that 8.5% had these deposits, with a notable correlation to factors like male gender, younger age, and higher serum uric acid levels.
  • The findings suggest that hyperechoic deposits may indicate more serious kidney issues in CKD patients, particularly involving uric acid metabolism and kidney function.*
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The prostate-specific antigen (PSA) test contributes a lot to the diagnosis and treatment of prostate cancer (PCa) and, along with imaging-guided prostate biopsy, has improved the diagnosis rate of lower-risk PCa and the accuracy of its clinical staging. However, many questions and controversies remain as to the choice of optimal biopsy strategies. Scholars differ in views about how to utilize PCa-related biomarkers to optimize the detection of initial and repeat biopsies.

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Regulatory T (Treg) cells are potent suppressors that maintain immune homeostasis. Accumulation of Treg can inhibit effective immune responses in cancer patients, leading to tumor development and progression. Despite direct cytotoxicity, several chemotherapeutic drugs have been reported to deplete Treg cells for better prognosis for cancer patients.

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Article Synopsis
  • - We conducted a meta-analysis of two studies on coronary artery disease with over 1,500 cases and 5,000 controls, focusing on individuals of Chinese Han ancestry.
  • - Our analysis identified four new genetic loci associated with coronary artery disease that reached significant levels of evidence, located near specific genes (TTC32-WDR35, GUCY1A3, C6orf10-BTNL2, and ATP2B1).
  • - We also confirmed four previously known loci linked to coronary artery disease in European populations, enhancing our understanding of genetic factors affecting this condition in the Chinese Han population.
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Background: Increased blood pressure and elevated total cholesterol (TC) level are the two most important modifiable risk factors of cardiovascular disease (CVD) in the world. Hypertension and hypercholesterolemia co-exist more often than would be expected and whether there is a synergistic impact on fatal CVD between elevated TC and hypertension need to be further examined in Chinese population.

Methods: We conducted a cohort study which recruited 5092 Chinese male steelworkers aged 18 - 74 years in 1974 - 1980 and followed up for an average of 20.

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Background: Cardiovascular disease (CVD) constitutes a major public health problem in China and worldwide. We aimed to examine classical risk factors and their magnitudes for CVD in a Chinese cohort with over 20 years follow-up.

Methods: A cohort of 5092 male steelworkers recruited from 1974 to 1980 in Beijing of China was followed up for an average of 20.

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Objective: Total cholesterol (TC) is an important risk factor for myocardial infarction (MI), but the effect of TC on MI in Chinese male hypertension population has not been well documented. We conducted a prospective cohort study to determine the incidence and relative risk for MI across a wide range of TC levels in Chinese male hypertension population.

Methods: A cohort of 5298 male employees aged 18-74 years recruited from Capital Steel and Iron Company in Beijing of China in 1974-1980 was followed up for an average of 20.

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Background: It is still uncertain whether increased blood pressure (BP) has a stronger effect on the risk of cardiovascular disease (CVD) in lean persons than in obese persons. We tested it using a data set collected from a large cohort of Chinese adults.

Methods: Systolic and diastolic BP, body mass index (BMI) and other variables were measured in 169,871 Chinese men and women > or = 40 years of age in 1991 using standard protocols.

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Article Synopsis
  • A study was conducted on 169,871 Chinese adults aged 40 and older to examine the relationship between BMI and stroke incidence and mortality, finding that higher BMI is linked to a greater risk of strokes.
  • Data was collected in 1991 and followed up in 1999-2000, with 7,489 strokes recorded over an average of 8.3 years of follow-up.
  • The research revealed that underweight individuals had a lower risk of stroke compared to normal weight, while overweight and obese individuals had significantly higher risks for both types of strokes and for stroke-related death.
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Objective: To examine the excess risks associated with prehypertension and absolute benefit of treatment.

Methods: We conducted a prospective cohort study in 169 871 Chinese adults aged 40 years and older. Data on blood pressure and covariables were obtained at a baseline examination in 1991 and follow-up evaluation was conducted in 1999-2000.

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Objective: To examine factors related to blood pressure (BP) responses to dietary sodium and potassium interventions.

Methods: We conducted a dietary feeding study that included a 7-day low-salt intervention (51.3 mmol sodium/day), a 7-day high-salt intervention (307.

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Background: Smoking is a risk factor for many diseases and has been increasingly prevalent in economically developing regions of the world. We aimed to estimate the number of deaths attributable to smoking in China.

Methods: We conducted a large, prospective cohort study in a nationally representative sample of 169,871 Chinese adults who were 40 years of age or older.

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The random-zero sphygmomanometer has been widely used in observational studies and clinical trials for blood pressure measurement. We examined the agreement of blood pressure measurements between random-zero and standard mercury sphygmomanometers among 2007 Chinese study participants aged 15 to 60 years. Three blood pressure readings were obtained by trained observers using random-zero and standard mercury sphygmomanometers, respectively, in a random order.

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Background: We examined the relationship between hypertension subtype and cardiovascular disease incidence and mortality in Chinese adults.

Methods And Results: We conducted a prospective cohort study in a nationally representative sample of 169 871 Chinese men and women aged >or=40 years. Data on systolic (SBP) and diastolic blood pressure (DBP) and other variables were obtained at a baseline examination in 1991 with the use of standard protocols.

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Background: Observational studies suggest that moderate alcohol consumption may lower risk of myocardial infarction (MI) and coronary heart disease (CHD); yet, evidence for this comes almost entirely from Western populations.

Methods: We conducted a prospective cohort study in 64,597 Chinese men aged > or = 40 years who were free of clinical CHD at baseline examination. Data on frequency and type of alcohol consumed were collected at the baseline examination in 1991 using a standard protocol.

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Objective: To examine the association between blood pressure (BP) and mortality among patients with a history of cardiovascular disease (CVD) in China.

Methods: We conducted a prospective cohort study among 4195 CVD patients aged 40 years and older. Data on BP and covariables were obtained at a baseline examination in 1991 and follow-up evaluation was conducted in 1999-2000 using standard protocols.

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Article Synopsis
  • - The study aimed to assess the changes in Body Mass Index (BMI) and the rates of overweight (BMI ≥ 25 kg/m²) and obesity (BMI ≥ 30 kg/m²) among Chinese adults from 1991 to 1999-2000.
  • - Results showed a significant increase in mean BMI for both men (from 21.8 to 23.4 kg/m²) and women (from 21.8 to 23.5 kg/m²), alongside rising prevalence rates of overweight and obesity across all age groups and regions in China.
  • - The findings highlight a notable escalation in overweight and obesity rates during the 1990s, indicating an urgent need for national initiatives aimed at
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Background And Purpose: We studied the relationship between cigarette smoking and stroke incidence and mortality in the Chinese adult population.

Methods: We conducted a prospective cohort study in a nationally representative sample of 169 871 Chinese men and women aged 40 years and older. Data on cigarette smoking and other covariables were collected at a baseline examination in 1991 using a standard protocol.

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Chronic obstructive pulmonary disease mortality and risk factors were studied in a nationally representative sample of 169,871 Chinese men and women aged 40 years or older. Baseline data were collected in 1991 by using a standard protocol, and a follow-up evaluation was conducted in 1999-2000, with a response rate of 93.4%.

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Article Synopsis
  • A study involving 169,871 adults aged 40 and older in China was conducted to explore the link between blood pressure levels and cardiovascular disease (CVD) incidence.
  • After adjusting for various factors like age, lifestyle, and geography, a significant and linear correlation was found between both systolic and diastolic blood pressure and the risk of CVD, coronary heart disease, and stroke.
  • The findings suggest that higher systolic blood pressure is a stronger predictor of CVD risk than diastolic pressure, impacting individuals across different demographics.
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Background: The relationship between body mass index (BMI) and risk of end-stage renal disease (ESRD) in Asians has not been well established.

Study Design: Prospective cohort study.

Setting & Participants: 143,802 men and women 40 years and older in China.

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Objective: Stroke is a leading cause of death and long-term disability in China. The objective of this study was to examine the relation between alcohol consumption and risk for stroke among Chinese men.

Methods: We conducted a prospective cohort study among 64,338 Chinese men aged > or = 40 years who were free of stroke at baseline.

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Synopsis of recent research by authors named "Xiufang Duan"

  • - Xiufang Duan's recent research primarily focuses on the application of advanced imaging techniques and biomarker studies in assessing renal artery stenosis, with findings highlighting the efficacy of renal fractional flow reserve (rFFR) compared to traditional methods such as angiography and color Doppler ultrasonography in detecting significant renal artery stenosis.
  • - In addition to renal health, Duan has explored the psychological aspects of postpartum experiences, conducting a bibliometric analysis of post-traumatic growth after childbirth, revealing trends and significant research gaps in this area.
  • - Duan's work also includes studies on chronic kidney disease, specifically investigating the presence of hyperechoic crystal deposits and their clinical relevance, indicating a potential novel diagnostic marker for related conditions in this patient population.