Publications by authors named "Xiuan Zeng"
Article Synopsis
- HIF-1α plays a crucial role in helping tissues adapt to low oxygen conditions and this study looks at its effects on blood vessel formation in specific surgical flaps used in rats.
- The research involved 90 male Wistar rats divided into three groups, receiving different treatments after flap surgery to measure angiogenesis, using various testing methods including x-ray angiography and histological analysis.
- Results indicated that the group treated with DMOG showed significantly increased blood vessel density and higher levels of HIF-1α and VEGF compared to the other groups, suggesting that HIF-1α enhances blood vessel growth and may improve tissue survival in these surgical procedures.
[Limited internal fixation combined with a hinged external fixator in treatment of peri-elbow bone infection].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
June 2023
Objective: To evaluate the effectiveness of limited internal fixation combined with a hinged external fixator in the treatment of peri-elbow bone infection.
Methods: The clinical data of 19 patients with peri-elbow bone infection treated with limited internal fixation combined with a hinged external fixator between May 2018 and May 2021 were retrospectively analyzed. There were 15 males and 4 females with an average age of 44.
[Effect of dimethyloxalylglycine on angiogenesis in Choke Ⅱ zone of cross-zone perforator flap and its mechanism].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
February 2022
Article Synopsis
- The study aimed to assess how dimethyloxalylglycine (DMOG) impacts blood vessel formation (angiogenesis) in a specific area of rats' skin flaps (Choke II zone) and to explore the mechanisms involved.
- A total of 126 male rats were divided into three groups: DMOG, YC-1, and a control group, with varying treatments to measure flap survival and angiogenesis over a week post-surgery.
- Results showed that the DMOG group had significantly higher flap survival rates (90.28%) and better vascular structure compared to the other groups, which experienced necrosis and less angiogenesis.