CtWD40-6 enhances the UV-B tolerance of safflower by regulating flavonoid accumulation.

Moderate UV-B promotes plant growth, but excessive UV-B inhibits plant development. The induction mechanism of how CtWD40-6 responds to UV-B is still unclear in safflower. Our results showed that CtWD40-6 is expressed at the top of safflower leaves and is strongly induced by UV-B.

Safflower CtFT genes orchestrating flowering time and flavonoid biosynthesis.

Background: Safflower thrives in dry environments but faces difficulties with flowering in wet and rainy summers. Flavonoids play a role in flower development and can potentially alleviate these challenges. Furthermore, the FLOWERING LOCUS T (FT) family of phosphatidylethanolamine-binding protein (PEBP) genes play a crucial role in the photoperiodic flowering pathway.

Interfacial engineering-based colonization of biofilms on polyethylene terephthalate (PET) surfaces: Implications for whole-cell biodegradation of microplastics.

Microplastic pollution has become a significant environmental issue. One of the most important sources and components of microplastics is polyester fabric - polyethylene terephthalate (PET). Because the catalytic depolymerization of PET typically requires specific conditions such as alkaline environments, specific solvents, or high temperatures, there is an urgent need for a simpler, eco-friendly solution with high degradation efficiency for managing the vast amounts of PET textile waste.

Integrated Metabolomics and Transcriptomics Provide Key Molecular Insights into Floral Stage-Driven Flavonoid Pathway in Safflower.

Safflower ( L.) is a traditional Chinese medicinal herb renowned for its high flavonoid content and significant medicinal value. However, the dynamic changes in safflower petal flavonoid profiles across different flowering phases present a challenge in optimizing harvest timing and medicinal use.

A wearable sensor based on janus fabric upon an electrochemical analysis platform for sweat glucose detection.

Wearable sweat sensing devices have drawn much attention due to their noninvasive and portable properties, which is emerging as a promising technology in daily healthiness assessment issues. A sweat sensor based on Janus fabric and electrochemical analysis is proposed in this work. Unidirectional moisture transported behavior of the Janus fabric serves as the quick-drying component directly contacting skin to transfer sweat toward the detection site.

Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) gene polymorphisms and five related serum molecular levels in 2587 patients: Associated differentially with adverse pregnancy.

Background: The aim of the study is to investigate the relationship between Methylenetetrahydrofolate reductase (MTHFR), methionine synthase reductase (MTRR) polymorphisms, 5 serum related molecular levels and the risk of adverse pregnancies in different genders.

Methods: Patients aged from 22 to 38 with a history of adverse pregnancy treated in our genetic eugenics clinic of Henan Provincial People's Hospital are selected. The controls aged from 20 to 34 undergoing eugenics examinations in our genetic eugenics clinic that had no history of adverse pregnancy and at least one healthy child are selected.

A sensor platform based on SERS detection/janus textile for sweat glucose and lactate analysis toward portable monitoring of wellness status.

Herein we report a wearable sweat sensor of a Janus fabric based on surface enhanced Raman scattering (SERS) technology, mainly detecting the two important metabolites glucose and lactate. Janus fabric is composed of electrospinning PU on a piece of medical gauze (cotton), working as the unidirectional moisture transport component (R = 1305%) to collect and transfer sweat efficiently. SERS tags with different structures act as the probe to recognize and detect the glucose and lactate in high sensitivity.

Safflower -Induced Drought Tolerance by Stimulating the Accumulation of Flavonols and Anthocyanins in .

Flavonol synthase gene () is a member of the 2-oxoglutarate-dependent dioxygenase () superfamily and plays an important role in plant flavonoids biosynthetic pathways. Safflower ( L.), a key source of traditional Chinese medicine, is widely cultivated in China.

The Carthamus tinctorius L. genome sequence provides insights into synthesis of unsaturated fatty acids.

Domesticated safflower (Carthamus tinctorius L.) is a widely cultivated edible oil crop. However, despite its economic importance, the genetic basis underlying key traits such as oil content, resistance to biotic and abiotic stresses, and flowering time remains poorly understood.

Cu/Co Bimetallic Carbon Catalyst as a Highly Efficient Promoter for Reactive Dyes Degradation with PMS.

The synergistic effect between bimetallic catalysts has been confirmed as an effective method for activating persulfate (PMS). Therefore, we immobilized copper-cobalt on chitosan to prepare bimetallic carbon catalysts for PMS activation and degradation of reactive dyes. Experimental results demonstrate that the CuCo-CTs/PMS catalytic degradation system exhibits excellent degradation performance toward various types of reactive dyes (e.

Instant mucus dressing of PEO reinforced by chitosan nanofiber scaffold for open wound healing.

Dressings seamlessly attached to the open wound bed are necessary for fully unleashing the dressing healing ability, as leaving the voids beneath the dressing poses infection hazards. The present study prepared an instant mucus dressing (IMD) of polyethylene oxide (PEO) reinforced by chitosan (CS) nanofiber scaffold, which formed by immersing PEO/CS nanofiber mat in water. The PEO/CS nanofiber mat were fabricated by the solution blow spinning (SBS) method using PEO and CS mixed solutions.

Novel multifunctional environmentally friendly degradable zeolitic imidazolate frameworks@poly (γ-glutamic acid) hydrogel with efficient dye adsorption function.

Recently, metal-organic frameworks (MOFs) have been widely developed due to the rich porosity, excellent framework structure and multifunctional nature. Meanwhile, a series of MOFs crystals and MOF-based composites have been emerged. However, the widespread applications of MOFs are hindered by challenges such as rigidity, fragility, solution instability, and processing difficulties.

Preparation of multifunctional cellulose macromolecule blended fabrics through internal and external synergy by N, N-bis (ethylene oxide-2-ylmethyl) hexane-1,6-diamine.

With the diversification of people's demand for textile functions, the preparation of multifunctional fabrics is still a current research hotspot. In this study, the water-soluble epoxy compound N, N-bis(oxiran-2-ylmethyl) hexane-1,6-diamine (EH) was introduced into cellulose macromolecule blended fabrics (cotton/modal) by two-phase vaporization technique, resulting in excellent wrinkle, hydrophobicity, and certain UV protection effects. It could be observed by electron microscopy that EH formed a polymer film on the fiber surface.

Enhancing La(III) biosorption and biomineralization with Micromonospora saelicesensis: Involvement of phosphorus and formation of monazite nano-minerals.

The release of rare earth elements (REEs) from mining wastes and their applications has significant environmental implications, necessitating the development of effective prevention and reclamation strategies. The mobility of REEs in groundwater due to microorganisms has garnered considerable attention. In this study, a La(III) resistant actinobacterium, Micromonospora saelicesensis KLBMP 9669, was isolated from REE enrichment soil in GuiZhou, China, and evaluated for its ability to adsorb and biomineralize La(III).

Simplicispira sedimenti sp. nov., isolated from a sediment of drainage ditch in winery.

A Gram-stain-negative, motile (by single polar flagellum) and rod-shaped bacterium, designated W1-6, was isolated from a sediment of drainage ditch in winery in Guiyang, south-western China. Strain W1-6 showed the highest 16S rRNA gene sequence similarities with the type strain of Acidovorax wautersii (98.1%) and Simplicispira lacusdiani (97.

Effects of multi-heavy metal composite pollution on microorganisms around a lead-zinc mine in typical karst areas, southwest China.

Heavy metal pollution poses a serious hazard to the soil bacterial community. The purpose of this study is to understand the characteristics of soil heavy metal pollution in lead-zinc mines in karst areas and the response of Pb, Zn, Cd, and As-induced composite pollution to soil microorganisms. This paper selected soil samples from the lead-zinc mining area of Xiangrong Mining Co.

Unraveling the functional characterization of a jasmonate-induced flavonoid biosynthetic CYP45082G24 gene in Carthamus tinctorius.

The cytochrome P450 superfamily of monooxygenases plays a major role in the evolution and diversification of plant natural products. The function of cytochrome P450s in physiological adaptability, secondary metabolism, and xenobiotic detoxification has been studied extensively in numerous plant species. However, their underlying regulatory mechanism in safflower still remained unclear.

Safflower Flavonoid 3'5'Hydroxylase Promotes Methyl Jasmonate-Induced Anthocyanin Accumulation in Transgenic Plants.

Flavonoids are the most abundant class of secondary metabolites that are ubiquitously involved in plant development and resistance to biotic and abiotic stresses. Flavonoid biosynthesis involves multiple channels of orchestrated molecular regulatory factors. Methyl jasmonate (MeJA) has been demonstrated to enhance flavonoid accumulation in numerous plant species; however, the underlying molecular mechanism of MeJA-induced flavonoid biosynthesis in safflower is still not evident.

Construction of the prognostic model for small-cell lung cancer based on inflammatory markers: A real-world study of 612 cases with eastern cooperative oncology group performance score 0-1.

Objectives: This research aimed to explore the relationship between pre-treatment inflammatory markers and other clinical characteristics and the survival of small-cell lung cancer (SCLC) patients who received first-line platinum-based treatment and to construct nomograms for predicting overall survival (OS) and progression-free survival (PFS).

Methods: A total of 612 patients diagnosed with SCLC between March 2008 and August 2021 were randomly divided into two cohorts: a training cohort (n = 459) and a validation cohort (n = 153). Inflammatory markers, clinicopathological factors, and follow-up information of patients were collected for each case.

A Cinnamate 4-HYDROXYLASE1 from Safflower Promotes Flavonoids Accumulation and Stimulates Antioxidant Defense System in Arabidopsis.

C4H (cinnamate 4-hydroxylase) is a pivotal gene in the phenylpropanoid pathway, which is involved in the regulation of flavonoids and lignin biosynthesis of plants. However, the molecular mechanism of C4H-induced antioxidant activity in safflower still remains to be elucidated. In this study, a CtC4H1 gene was identified from safflower with combined analysis of transcriptome and functional characterization, regulating flavonoid biosynthesis and antioxidant defense system under drought stress in Arabidopsis.

Understanding the Relationships between Landscape Eco-Security and Multifunctionality in Cropland: Implications for Supporting Cropland Management Decisions.

Cropland is an essential strategic resource, for which landscape ecological security and multifunctionality evolution are related to regional stability and sustainable social development. However, few studies have explored the spatial heterogeneity of the coupling between the two from a multiregional and systematic perspective, and the interaction mechanisms have still not been thoroughly analyzed. In this study, a typical karst trough and valley area in the mountainous regions of southwest China was selected as the research object, and by establishing a multi-indicator evaluation system using a landscape pattern index, a multifunctional identification model, a coupled coordination model, and a geodetector model, the spatial variability in the evolutionary characteristics and the coupling and coordination of cropland landscape ecological security (CLES) and cropland multifunctionality (CM) in the mountainous regions of the southwest and their driving mechanisms were explored.

MiR-29b level-mediated regulation of Klotho methylation via DNMT3A targeting in chronic obstructive pulmonary disease.

Chronic obstructive pulmonary disease (COPD) is a chronic lung disease characterized by chronic bronchitis and emphysema. Cigarette smoke extract (CSE) is the predominant cause of COPD. This study aimed to investigate the effects of miR-29b and their underlying mechanisms in a COPD cell model.

The safflower MBW complex regulates HYSA accumulation through degradation by the E3 ligase CtBB1.

The regulatory mechanism of the MBW (MYB-bHLH-WD40) complex in safflower (Carthamus tinctorius) remains unclear. In the present study, we show that the separate overexpression of the genes CtbHLH41, CtMYB63, and CtWD40-6 in Arabidopsis thaliana increased anthocyanin and procyanidin contents in the transgenic plants and partially rescued the trichome reduction phenotype of the corresponding bhlh41, myb63, and wd40-6 single mutants. Overexpression of CtbHLH41, CtMYB63, or CtWD40-6 in safflower significantly increased the content of the natural pigment hydroxysafflor yellow A (HYSA) and negatively regulated safflower petal size.