[Relationship between the level of waist circumference and the impaired fasting glucose of pre-diabetes].

Objective: To explore the relationship between the level of waist circumference (WC) and the impaired fasting glucose (IFG) in people working for the Kailuan Enterprise.

Methods: A total of 101 510 subjects from the employees of Kailuan Group who took part in the health examination between 2006 to 2007, with fasting plasma glucose (FPG) < 6.1 mmol/L, no history of diabetes, completed data on FPG and WC examination and without using hypoglycemic agents, were selected as the observation cohort.

[Impact of the waist circumference change on new onset of diabetes in the population with impaired fasting glucose].

Objective: To explore the impact of the waist circumference change on new onset diabetes (NOD) in the impaired fasting glucose (IFG) population.

Methods: A total of 12 657 subjects who took part in the health examination from 2006 to 2007 and from 2010 to 2011 from the employees of Kailuan Group and met the inclusion criteria were selected as the observation cohort.Of the 12 657 subjects, 10 697 were male, 1960 were female, with age of (49.

[Association between blood pressure level and incidence of carotid artery plaque in middle-aged and elderly people].

Objective: To explore the association between blood pressure level and incidence of carotid arterial plaque in middle-aged and elderly people.

Methods: A total of 5852 individuals were randomly stratified from the 101 510 health examination survey participants in Tangshan Kailuan Company community during 2006-2007. A total of 5440 people (age above 40 years old, free of stroke, TIA and myocardial infarction) were enrolled in the final analysis.

[Impact of baseline pulse pressure on new-onset cardio-and cerebrovascular events in diabetic population].

Objective: To observe the association between baseline pulse pressure (PP) level and new-onset cardio-cerebrovascular events in diabetic population.

Methods: Physical examination data between July 2006 to October 2007 from a total of 101 510 employees of Kailuan Group were reviewed, 8306 subjects with a fasting plasma glucose level of ≥ 7.0 mmol/L or with confirmed diabetes diagnosis and were enrolled in this prospective cohort study.

[The prevalence and distribution of ideal cardiovascular health behavior in employees of Kailuan Group cohort].

Objective: To observe the prevalence and distribution of ideal cardiovascular health behavior.

Methods: Health examination data between 2008 to 2009 from the employees of Kailuan Group were analyzed.

Results: A total of 101 333 subjects took part in the health examination, subjects with previous myocardial infarction (n = 871), stroke (n = 2255), myocardial infarction and stroke (n = 162) and subjects with incomplete examination data (n = 9311) were excluded and 88 534 subjects were included for final analysis [mean age (50.

[Association between baseline high sensitivity C-reactive protein level and the first cardio-cerebral vascular event in diabetic population: a prospective cohort study].

Objective: To evaluate the predictive value of baseline serum high sensitivity C-reactive protein for the first cardio-cerebral vascular event in the population with diabetes.

Method: In this prospective cohort study, a total of 101 510 employees of Kai Luan Group, who received healthy examination from July 2006 to October 2007, were screened and 7865 subjects with fasting plasma glucose ≥ 7.0 mmol/L or known diabetes mellitus and under insulin or hypoglycemic drugs therapy were followed up for 38 - 53 (48.

[Clinical features and serologic analysis of latent syphilis].

Objective: To summarize the clinical features and analyze the serologic test results of latent syphilis.

Methods: The clinical data of 601 patients with latent syphilis who were treated in the sexually transmitted disease centre of Peking Union Medical College Hospital between January 2001 and November 2007 were retrospectively analyzed.

Results: Of the 601 cases of latent syphilis, there were 174 cases of early latent syphilis(EL), 170 cases of late latent syphilis(LL), and 257 cases of unknown latent syphilis.

[Analysis of 1125 syphilis cases].

Objective: To summarize the epidemiological, clinical and serological features of syphilis.

Method: The clinical data of 1125 patients with syphilis were retrospectively analyzed.

Results: Non-marital sexual intercourse is the main route of infection.

5-aminolaevulinic acid-photodynamic therapy for the treatment of cervical condylomata acuminata.

Objective: To investigate the efficacy and safety of photodynamic therapy (PDT) with topical 5-aminolaevulinic acid (ALA) on cervical condylomata acuminata.

Methods: Patients with cervical condylomata (n=30) were allocated into primary and recurrent group, and were given topical ALA under occlusive dressing for 3 hours followed by irradiation with semiconductor laser at a dose of 100 Jcm(-2) and a power of 100 mW. The treatment was repeated 7 days later if the lesion was not completely removed after the first treatment.

[Clinical analysis and study of immunological function in syphilis patients with seroresistance].

Objective: To investigate the relevant factors of seroresistance of syphilis by clinical analysis and study of immunological function.

Methods: The clinical data of 172 patients with syphilis were analyzed to observe the correlation of seroresistance with the factors including original titer of rapid plasma regain (RPR), disease course, and medication. Flow cytometry was used to analyze the proportions of T-lymphocyte subset and NK cells in the peripheral blood of 40 untreated syphilitic patients at various stages, 20 syphilitic patients whose serology turned negative after treatment, 20 serum resistance patients, and 18 healthy controls.

[Knowledge and attitudes towards second hand smoking among hospitality patronage in five cities in China].

Objective: To understand the knowledge and attitudes towards second hand smoking (SHS) among restaurant or bar patronage in five cities in China.

Methods: 405 restaurants and bars were conveniently selected in 5 cities as Beijing, Wuhan, Xi'an, Kunming and Guiyang. From each of these hospitality venues, at least 3 patrons, including one smoker, one female non-smoker and one male nonsmoker were asked to answer a questionnaire on their knowledge and attitudes towards SHS and smoking policies in public places.

[Incidence of seroresistance of syphilis and its relevant factors].

Objective: To investigate the incidence of seroresistance of syphilis and analyze its relevant factors.

Methods: The clinical data of 131 patients with syphilis were retrospectively analyzed. The incidence of seroresistance was investigated and the correlation between seroresistance and factors including age, gender, original titer, disease course, and medications were analyzed.

[Relationship between CCR5 gene polymorphism and condyloma acuminata].

Objective: To investigate the relationship between CCR5 delta32 gene polymorphism and condyloma acuminata.

Methods: We used polymerase chain reaction to amplify the CCR5 gene fragments in 60 patients with condyloma acuminata and 50 age- and sampling date-matched controls, and compared the difference of genotypes between these two groups.

Results: No genotype difference was found between these two groups.

[Sensitivity and specificity of ELISA based on recombinant Treponema pallidum antigen and rapid plasma reagin test in diagnosis of syphilis: a comparative study].

Objective: To compare the sensitivity and specificity between ELISA based on the recombinant Treponema pallidum (Tp) antigen and rapid plasma reagin (RPR) test diagnosis of syphilis.

Methods: Peripheral blood samples were collected from 249 patients, 177 males and 72 females, aged 34. Abbott Determine Syphilis TP test (ELISA based on the recombinant Tp antigen), RPR test, and Treponema pallidum haemagglutination assay (TPHA) were conducted with TPHA used as the gold standard.