Fever with thrombocytopenia associated with a novel bunyavirus in China.

Background: Heightened surveillance of acute febrile illness in China since 2009 has led to the identification of a severe fever with thrombocytopenia syndrome (SFTS) with an unknown cause. Infection with Anaplasma phagocytophilum has been suggested as a cause, but the pathogen has not been detected in most patients on laboratory testing.

Methods: We obtained blood samples from patients with the case definition of SFTS in six provinces in China.

[Epidemiologie investigation on murine typhus in Hongta areas of Yuxi city, Yunnan province of China].

Objective: To identify epidemic status of murine typhus in Hongta areas of Yuxi city and to provide evidence for control and prevention of the disease.

Methods: Serologic survey was conducted among residents and rodents. Isolation of Rickettsia moseri was performed.

[Surveillance on Rickettsia in epidemic areas of scrub typhus in Xinyang areas of Henan].

Objective: To understand the epidemic status of Rickettsia in Xinyang areas of Henan province.

Methods: Samples including liver, spleen, kidney from mouse and chigger mites from Xinyang areas and serum samples were detected by nested-polymerase chain reaction (PCR) and indirect immunofluorescence assay (IFA).

Results: In 62 viscus samples from mice organs, the positive rates were 16.

Molecular epidemic survey on co-prevalence of scrub typhus and marine typhus in Yuxi city, Yunnan province of China.

Background: Human rickettsioses are worldwide zoonoses and it is not easy to differentiate them from other infectious diseases because of their atypical manifestation. In recent years the number of patients with fever of unknown causes from Hongta District CDC, Yuxi city of Yunnan Province has been increasing significantly in the summer. Diagnosis of scrub typhus was made by local clinicians.

[Use of variable-number tandem repeats to examine genetic diversity of Bacillus anthracis].

Objective: To study the genotyping of Bacillus anthracis based on multiple-locus variable-number tandem repeats(VNTR) in the B. anthracis genome.

Methods: We selected 13 VNTR loci (which cited from published articles) to study 88 strains of B.

Genetic differentiation of Chinese isolates of Rickettsia sibirica by partial ompA gene sequencing and multispacer typing.

Current data on rickettsiae and rickettsial diseases in China remain limited. Using partial ompA gene sequencing and multispacer typing, we identified 15 rickettsial isolates from China. All isolates were found to belong to Rickettsia sibirica subsp.