[Clinical features of preeclampsia-eclampsia patients with reversible posterior leukoencephalopathy syndrome].

Objective: To investigate the clinical features and specific characteristics of magnetic resonance image (MRI) in preeclampsia-eclampsia patients with reversible posterior leukoencephalopathy syndrome (RPLS).

Methods: The investigators analyzed the combined clinical, laboratory and neuroradiographic features of 20 preeclampsia-eclampsia patients with RPLS and 15 preeclampsia-eclampsia controls with normal MRI findings.

Results: Patients with RPLS had more tendency to have headache, seizure, visual disturbance, confusion and altered mental status than controls.

[Study on the association between gestational diabetes mellitus and tumor necrosis factor-alpha gene polymorphism].

Objective: To study allelic frequency of tumor necrosis factor-alpha (TNF-alpha) in gestational diabetes mellitus (GDM) of Han ethnicity in north China and to determine whether there is a specific allele of TNF-alpha associated with GDM susceptibility.

Methods: By using PCR-RFLP, we detected the distribution of TNF-alpha promoter alleles frequency in GDM women and control normal pregnant women. Plasma TNF-alpha levels and insulin levels were measured by radioimmunoassay.

[Study on association between gestational diabetes mellitus and sulfonylurea receptor-1 gene polymorphism].

Objective: To investigate allelic frequency of sulfonylurea receptor-1 (SUR1) in gestational diabetes mellitus (GDM) women of Han nationality in north China in order to find out susceptible gene associated with GDM, and to assess the association between SUR1 allele and body mass index (BMI) and secretion of insulin.

Methods: Seventy cases of pregnant women were selected. It included 35 cases of pregnant women with GDM (GDM group), 35 cases of normal pregnant women (normal control group).