Sichuan Da Xue Xue Bao Yi Xue Ban
January 2017
Objectives: To investigate the Wnt5a expression in obese mice with hepatocellular carcinoma.
Methods: Two groups of 6-week C57BL/6J mice were fed with chow-diet and high-fat-diet for 8 weeks respectively, to establish obesity model in the latter group. Mice in Hepal-6 group (including normal-body mass mice and obese mice) were injected with Hepa1-6 hepatocarcinoma cell lines through caudal vein, while the controls were given NS.