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[The effect of bone marrow mesenchymal stem cell transplantation on hypoxic pulmonary hypertension in rats].
Hong-Jun Tian Jing-Ping Yang Xiu-Xiang Wang

Zhongguo Ying Yong Sheng Li Xue Za Zhi

May 2014

Objective: To study the influence of bone marrow mesenchymal stem cells (MSCs) transplantation on hypoxic pulmonary hypertension (HPH) in rats.

Methods: SD rats MSCs were separated, cultivated, identified and labeled by the green fluorescence protein (GFP) gene virus and transplanted in vitro. Healthy male SD rats were randomly divided into four groups: Normal control group (NC group) and HPH group (eight rats respectively), HPH+ MSCs transplantation group and HPH+ VEGF+ MSCs transplantation group (twenty-four respectively).

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