Publications by authors named "Xiu-Shan Hu"
Involvement of clathrin-dependent endocytosis in cellular dsRNA uptake in aphids.
Insect Biochem Mol Biol
May 2021
Article Synopsis
- RNA interference (RNAi) is a crucial tool for understanding gene function in eukaryotes and has potential for pest management, but the uptake mechanism of dsRNA in aphids is not well understood.
- Researchers focused on pea aphids and identified two key genes associated with clathrin-dependent endocytosis (CDE), which play a role in the cellular uptake of dsRNA.
- By using various methods, including an RNAi strategy and inhibitors, the study suggested that CDE is essential for the effective uptake and silencing of genes by dsRNA in both pea aphids and peach aphids.