[Effects of weight-bearing ladder and aerobic treadmill exercise on learning and memory ability of diabetic rats and its mechanism].

Objective: To investigate the effects of climb ladder and aerobic treadmill exercise on learning memory ability in diabetic rats and explore its possible mechanisms.

Methods: Forty male rats were randomly divided into normal control group (NC), diabetic control group (DC), diabetic loading ladder group (DL) and diabetic aerobic treadmill group (DA), diabetes was induced by a single intraperitoneal injection of STZ. In the evening, the DL group were trained three cycle (10 times/cycle) with weight-bearing climbing ladder, 2 min intervals, 6 days/week, lasted for six weeks.