[Characteristics of agricultural climate resource changes during the growth stages of tobacco during 1961-2017 in Panxi Region, China].

It is of great significance for the sustainable development of regional agriculture to understand the changes of agricultural climate resources during the growth period of local main crops. Based on data from 15 meteorological stations in tobacco planting area of Panxi region, Sichuan, from 1961 to 2017, the average temperature, diurnal temperature range, water deficit, and radiation were used to analyze the temporal and spatial distribution of agricultural climate resources such as light, temperature, and water in the whole growth period and each growth stages respectively. From 1961 to 2017, the average temperature of tobacco during the whole growth period gradually decreased from south to north in Panxi, while temperature showed an increasing trend in most areas.

Interleukin-36 receptor antagonist attenuates atherosclerosis development by inhibiting NLRP3 inflammasome.

Atherosclerosis is characterized, as an inflammatory disorder in the circulatory system, with increasing tendency toward mortality and morbidity. Thus, developing novel therapeutic targeting inflammation is necessary. Here, we investigated the effects of interleukin-36 receptor antagonist (IL-36RN), a newly identified anti-inflammatory factor, on atherosclerosis.

[Shenfu injection induces the apoptosis of prostate cancer PC-3 cells].

Objective: To study the effect of Shenfu Injection (SF) on the apoptosis of prostate cancer PC-3 cells and its possible mechanism.

Methods: We divided prostate cancer PC-3 cells into a blank control group and three experimental groups, the latter treated with SF at 50, 100, and 200 microl/ml, respectively, for 24, 48, and 72 hours. Then we determined the proliferation of the cells by MTT assay, measured their apoptosis by Annexin V/PI flow cytometry, and detected the expression of P53 mRNA by RT-qPCR.