PFP alleviates nonalcoholic steatohepatitis fatty liver in both Apo E mice and Changliver cell[S].

High-calorie food leads to nonalcoholic fatty liver disease (NAFLD) through the dysregulation of genes involved in lipid metabolism, but the precise mechanism is still unknown. Pomegranate flowers are used to treat diabetes mellitus in traditional Uighur medicine. Here we sought to investigate the effect and mechanism of pomegranate flower polyphenols (PFP) on NAFLD Apo E mice induced by a high-fat diet (HFD) and whether PFP improves NAFLD through decreasing oxidative stress.