Factors Influencing the Demoralisation Syndrome of Post-Operative Patients With Breast Cancer: A Cross-Sectional Study.

Aim: We explored demoralisation syndrome among post-operative patients with breast cancer and its relationship with patients' body image and marital intimacy.

Design: A cross-sectional study.

Methods: In this cross-sectional study, 237 patients with breast cancer who were hospitalised in the breast surgery department of Grade A tertiary hospital in Xiamen, China from June 2022 to December 2023 and met the standards of adaxation were selected by the convenience sampling method.

Antimicrobial Resistance and Genomic Characterization of and Isolated from Retail Chickens in Beijing, China.

Objective species are the main causes of foodborne illness worldwide, posing significant threats to public health. This study aimed to investigate the antibiotic resistance and genomic characterization of / from retail chickens in Beijing. Methods Antimicrobial susceptibility testing was conducted on 126 / isolated from retail chickens in Beijing, following CLSI protocols.

Prediction of Prognosis in Patients with Sepsis Based on Platelet-Related Genes.

The study aimed to develop a risk prognostic model using platelet-related genes (PRGs) to predict sepsis patient outcomes. Sepsis patient data from the Gene Expression Omnibus (GEO) database and PRGs from the Molecular Signatures Database (MSigDB) were analyzed. Differential analysis identified 1139 differentially expressed genes (DEGs) between sepsis and control groups.

Clinical definition of secondary resistance to immunotherapy in non-small cell lung cancer.

Immune checkpoint inhibitors (PD-1/PD-L1 and CTLA-4 blockade) have revolutionized the treatment landscape in non-small cell lung cancer (NSCLC). Secondary resistance to immunotherapy (IO), which poses a substantial challenge in clinical settings, occurs in several initial responders. Currently, new treatment approaches have been extensively evaluated in investigational studies for these patients to tackle this difficult problem; however, the lack of consistency in clinical definition, uniform criteria for enrollment in clinical trials, and interpretation of results remain significant hurdles to progress.

Identification of Dominant Strains in Liu Shenqu by MALDI-TOF MS and DNA Sequencing Methods.

Background: Liu Shenqu has been widely used to treat the illnesses of spleen and stomach, indigestion, etc. in China. As a fermented product, strains play an important role in the fermentation process, which will affect the quality of Liu Shenqu.

Dysbiosis of saliva microbiome in patients with oral lichen planus.

Background: Oral microbiota is not only important for maintaining oral health but also plays a role in various oral diseases. However, studies regarding microbiome changes in oral lichen planus (OLP) are very limited. To the best of our knowledge, there has been only two studies investigating salivary microbiome changes in OLP.

Effects of Periodontal Intervention on Levels of Serum High-sensitivity C-reactive Protein and Interleukin 6, and on Carotid Artery in Rats with Chronic Periodontitis and Hyperlipidemia.

Objective: To investigate the effects of nonsurgical periodontal therapy on the serum interleukin 6 (IL-6) and high-sensitivity C-reactive protein (hsCRP) and on the carotid artery in rats with chronic periodontitis (CP) and with or without hyperlipidemia (HL).

Methods: A total of 29 Sprague-Dawley rats were randomly divided into two groups: group A (CP, n = 14) and B (CP + HL, n = 15), and subjected to the corresponding treatment. Groups A and B were further divided into groups A1/B1 (without periodontal interventions) and A2/B2 (with periodontal interventions).

Proteomic Identification of Immune-Related Silkworm Proteins Involved in the Response to Bacterial Infection.

Bombyx mori (Lepidoptera: Bombycidae) is an important economic insect and a classic Lepidopteran model system. Although immune-related genes have been identified at a genome-wide scale in the silkworm, proteins involved in immune defense of the silkworm have not been comprehensively characterized. In this study, two types of bacteria were injected into the silkworm larvae, Gram-negative Escherichia coli (Enterobacteriales: Enterobacteriaceae), or Gram-positive Staphylococcus aureus (Bacillales: Staphylococcaceae).

Thermally activated delayed fluorescent (TADF) coordination polymer with the generation of singlet oxygen.

4,4'-{9,9'-Spirobi[10H-acridine]-10,10'-diyl}dibenzoic acid (L, CHNO) was designed and synthesized as a new donor-acceptor motif molecule. Due to the large dihedral angle between the planes of the carboxyphenyl group and the spiroacridine moiety, L possess thermally activated delayed fluorescence (TADF). By applying L as a ligand and using Cd as a metal connector, we synthesized the coordination polymer catena-poly[hemi-μ-aqua-aqua(μ-4,4'-{9,9'-spirobi[10H-acridine]-10,10'-diyl}dibenzoato)cadmium(II)], [Cd(CHNO)(HO)], (I).

Discriminatory Power Evaluation of Nuclear Ribosomal RNA Barcoding Sequences Through Related Samples.

Since the cost of has increased dramatically and the counterfeits may have adverse effect to health, a rapid and precise species-level DNA barcoding identification system could be a potent approach and significantly enhance the regulatory capacity. The discrimination power of three subunits sequences from nuclear ribosomal RNA gene cluster were determined by Simpson's index of discrimination using 43 wild fruiting bodies, pure cultures, commercial mycelium fermented powder and counterfeits. The internal transcribed spacer (ITS) sequences showed the highest variance and discrimination power among 43 samples, as determined by Simpson's index of discrimination ( = 0.

[Prevalence and characterization of cefotaxime and ciprofloxacin co-resistant Escherichia coli isolates in retail chicken carcasses].

Objective: To investigate the prevalence and characteristics of cefotaxime in co-resistant Escherichia coli isolates in retail chicken samples and provide or the risk assessment and evaluation of new control measures of multi-drug i isolates in retail chicken products.

Methods: Whole chicken carcasses re collected from Shanxi (n = 91), Guangdong (n = 63) and Inner 53) from April to December in 2011, cefotaxime and ciprofloxacin co- li isolates were recovered and subjected to phylogenetic group typing and usceptibility testing. All isolates were further characterized by screening for genes, quinolone resistance determinants by PCR and followed by DNA sis.

Functional characterization of quinolone-resistant mechanisms in a lab-selected Salmonella enterica typhimurium mutant.

Correlation has been widely accepted between quinolone resistance and topoisomerase point mutations in quinolone resistance determination regions (QRDRs). Acquirement of point mutations in QRDRs usually increases the microbial resistance to both nalidixic acid and fluoroquinolones. The quinolone-resistant mechanisms accumulated in a lab-selected mutant were characterized through the construction of isogenic mutants using phage λ Red recombinase system and phage P22.

[FBAT analysis of polymorphisms of vitamin D receptor (Taq I and Fok I) in aggressive periodontitis families].

Objective: To analyze the correlation between polymorphisms of the vitamin D receptor gene (Taq I and Fok I) and the aggressive periodontitis by FBAT method.

Methods: 93 AgP nuclear families including 93 probands and their 155 relatives were recruited. The genotype frequency and polymorphism for VDR for the patients and their pedigree were detected by using polymerase chain reaction (PCR) combined with restriction fragment length polymorphism (RFLP).