Effect of Water on the Structure and Stability of Hydrogen-Bonded Oxalic Acid Dimer.

As the simplest and most abundant dicarboxylic acid in the atmosphere, oxalic acid (OA) not only plays a key role in aerosol nucleation, but also acts as a prototypical compound for the investigation of intra- and intermolecular hydrogen-bonding interactions. A systematic theoretical study on the hydrated OA dimers performed by using DFT at the M06-2X/6-311++G(3df, 2p) level is discussed herein. The properties of hydrogen bonds in clusters are inspected through topological analysis by using atoms in molecules (AIM) theory.

Clinical and pathological characteristic of metastatic malignant mesothelioma initially diagnosed by lymph node biopsy.

Background: It is a great challenge for pathologists to initially diagnose metastatic malignant mesothelioma (MM) by the lymph node biopsy without any history of primary MM. Because the onset of MM is hidden and the metastatic MM in lymph node is relatively uncommon. Besides, morphologic and immuohistochemistry features of MM are similar to other tumors.

Is autologous or heterologous pericardium better for valvuloplasty? A comparative study of calcification propensity.

Pericardial calcification is detrimental to the long-term durability of valvuloplasty. However, whether calcification susceptibility differs between heterologous and autologous pericardium is unclear. In this study, we compared the progression of calcification in vivo between autologous and heterologous pericardium.

Endolymphatic sac tumor with von Hippel-Lindau disease: report of a case with atypical pathology of endolymphatic sac tumor.

The authors described a case of a patient with co-existing endolymphatic sac tumor (ELST) and hemangioblastoma in the posterior cranial fossa, which belonged to a subtype of Von Hippel-Lindau (VHL) disease confirmed by the test of VHL-gene. The signs in this 42-year-old female included intermittent headache and dizziness. Imaging revealed a giant mass in the right cerebellopontine angle (CPA) region and another lesion in the left cerebellar hemisphere.

Selective production of electrostatically-bound adducts of alkyl cations/polyoxoanions by the collision-induced fragmentations of their quaternary ammonium counterparts.

Solutions of the quaternary ammonium salts of a set of classic polyoxometalates (POMs) (Keggin [XM12O40](n-), Dawson [P2W18O62](6-), and Lindqvist [M6O19](2-) (X = P, Si; M = W, Mo) were characterized by electrospray mass spectrometry. The gas-phase fragmentations of a series of quaternary ammonium-associated clusters were investigated by their collision-induced dissociations to elucidate their fragmentation mechanisms. It was found that the quaternary ammonium-associated clusters had distinctive dissociation characteristics.

[Tumor microvascular density detected by anti-CD105 and anti-CD34 in hepatocellular carcinoma patients and its predictive value of tumor recurrence after liver transplantation].

Objective: To investigate the clinical significance of tumor microvascular density (MVD) detected by anti-CD105 and anti-CD34 as a predictor of recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT).

Methods: One hundred and twelve (100 with adjacent nontumorous area) patients with HCC who underwent LT between Jan. 2001 and Dec.

[Explorative study on mechanism and drug intervention for chronic allograft nephropathy induced by renal ischemia-reperfusion injury].

Objective: This study is aiming to investigate the mechanism and drug intervention of chronic allograft nephropathy (CAN) induced by renal ischemia-reperfusion injury.

Methods: The closed colony strain Sprague-Dawley (SD) and Wistar Rats were used as donor and recipient, respectively. Orthotopic kidney transplantation was performed following the procedure of our previous study.

[An analysis of long term prophylaxis of virus recurrence with antiviral treatment in HBV infected liver transplant recipient patients].

Objective: No optimal prophylactic protocol of hepatitis B immunoglobulin (HBIG) combined with nucleos(t)ide analogue for HBV recurrence has been established yet. By investigating the alterations of HBV markers in HBV related liver disease patients, recipients of a liver transplant, under lamivudine or/and HBIG prophylaxis, we aim to explore the possible HBV recurrence mechanism involved and to find a new option in the prophylaxis of HBV recurrence and to tailor individualized therapy.

Methods: Serial liver biopsy specimens and sera were obtained intraoperationally and at definite time points during follow-up.

Theoretical studies on novel main group metallocene-like complexes involving planar hexacoordinate carbon eta6-B6C2- ligand.

The geometric structures for a novel series of main group 1 and 2 metal atom complexes with planar hexacoordinate carbon dianion (eta6-B6C)2- ligand, involving metallocene-like, K[(eta6-B6C)Ca]n(eta6-B6C)K (n = 1-3) and [(eta6-B6C)Ca]n(eta6-B6C)2- (n = 1, 2), as well as relative pyramidal [(eta6-B6C)M]i- (M = Na, K, and CaCl, i = 1; M = Ca, i = 0) and bipyramidal (eta6-B6C)(CaCl)2, have been optimized to be the local minima on the corresponding potential hypersurfaces at the B3LYP/6-311+G(d) level of theory. Natural bond orbital analysis indicates that the electrostatic interaction between the metal ions and the planar hexacoordinate carbon B6C2- rings plays a crucial role in stabilizing these highly symmetrical complexes. The pi-d interaction in Ca-containing complexes also plays an important role in the stabilization of these molecules.

Dynamic CT Evaluation of Tumor Vascularity in Renal Cell Carcinoma.

Objective: The purpose of our study was to evaluate the correlation between the enhancement parameters of dynamic CT; the carcinoma tissue microvessel density (MVD, a hotspot method to provide a histologic assessment of tumor vascularity); and tumor nuclear grade in renal cell carcinomas.

Subjects And Methods: Twenty-four patients with histologically diagnosed renal cell carcinoma underwent dynamic enhanced CT. Enhancement parameters, slope of the time-density curve, the density difference before and after tissue enhancement (deltaH), tissue blood ratio (TBR), and area under the time-density curve (AR), were calculated for all lesions.

[Investigation on the alteration of hepatitis B virus (HBV) markers in liver allograft of HBV related recipients in perioperative period].

Objective: To investigate the alteration of HBV markers in liver allograft of HBV related recipients pre and post liver transplantation under Lamivudine or combination of Lamivudine with HBIG prophylaxis and explore the mechanism of HBV de nova infection in liver allograft after orthotopic liver transplantation, as well as seek to establish a optimal prophylactic protocol.

Methods: The serial liver biopsy specimens of 90 liver allograft and sera of 78 liver transplant recipients during operation and after 1 week, 1 month, 3 months, 6 months, 12 months, 24 months post transplantation have been collected and detected for HBV markers with enzyme-linked radioimmunoassay, fluorescent quantitative assay for HBV-DNA in serology and with immunohistochemistry stain, HBV-DNA in situ hybridization in histology for detection of HBV markers in liver allograft samples.

Results: Whether recipients with active replicative or inactive replicative HBV preoperatively, none of positive HBV-DNA, HBsAg and HBcAg in 100% liver biopsy specimens with HBV-DNA hybridization in situ and immunohistochemistry stains in histology within 2 hours after reperfusion.

[Clinical and pathological analyses of lipoprotein glomerulopathy].

Objective: To investigate the clinical and pathological characteristics of lipoprotein glomerulopathy.

Methods: We retrospectively analyzed 3 cases of lipoprotein glomerulopathy.

Results: The 3 patients, 1 male and 2 females, were young Hans.

[A new rat model of transplant kidney-sclerosis accelerated by prolonged cold ischemia time].

Objective: To establish an accelerated animal model of the chronic renal allograft dysfunction in rat.

Methods: Kidney transplantation was performed from SD to Wistar strain (allogeneic) according to the procedure of Kamada with some modification. Before the transplantation, the kidney was preserved in 0-4 degrees C heparin sodium chloride solution for prolonging the one hour.

Lamivudine prophylaxis of liver allograft HBV reinfection in HBV related cirrhotic patients after liver transplantation.

Background: Liver allograft hepatitis B virus (HBV) reinfection and hepatitis B (HB) recurrence jeopardize the long-term survival of recipient and liver allograft. Lamivudine has been referred as a novel antiviral agent against HBV in HBV cirrhotic patients even in liver transplantation setting. We assessed the prophylatic effect of lamivudine on liver allograft HBV reinfection and clarified the dynamic changes of HBV markers in HBV related decompensated liver cirrhosis after liver transplantation.

Dynamic alteration of HBV markers on active HBV replicative recipients after liver transplantation: a preliminary report.

Objective: To investigate the dynamic alternations of HBV markers of active HBV replication recipients receiving lamivudine prophylaxis after liver transplantation.

Methods: Serial liver biopsy samples and sera were obtained from 15 recipients and examined with enzyme-linked radioimmunoassay for HBsAg, HBeAg, HBsAb, HBcAb and HBeAb, and fluorescent quantitative assay for quantitation of HBV DNA in serum. Immunohistochemical staining of HBsAg, HBcAg and HBV DNA hybridization in situ were used to detect HBV markers in liver biopsy samples.