The effect of emotional uncertainty on attentional bias toward neutral infant faces in adults.

Recent studies have found that adults have stronger attentional bias toward neutral infant faces than emotional (positive or negative) infant faces. This phenomenon may derive from uncertainty over neutral expressions. To test this hypothesis, we recruited 176 participants to examine the relationship between their attentional bias toward neutral infant faces (with neutral adult faces as a comparison baseline) and their level of certainty in their appraisal of emotional valence through eye-tracking indices.

Sustainable oil-in-water analysis using a supercritical fluid carbon dioxide extraction system directly interfaced with infrared spectroscopy.

A direct aqueous supercritical fluid extraction (SFE) system using carbon dioxide provides a sustainable means by which a vast range of industries may continue to depend on well established infrared (IR) techniques to determine oil-in-water. The SFE-IR method provides an environmentally friendly substitute for current national standard IR reference methods for measuring oil-in-water that rely on using increasingly restricted ozone depleting solvents whose manufacture is being phased out in accordance with international law. The SFE-IR analysis of a 500 mL water sample can be accomplished in 15 min.

Direct aqueous supercritical fluid extraction coupled on-line with liquid chromatography-tandem mass spectrometry for the analysis of polyether ionophore antibiotics in water.

A direct aqueous SFE system designed to extract water samples contained in vials has been coupled on-line with a reverse phase LC-MS-MS system using a single 10-port valve. An SFE trap system using C(1) stationary phase connected to a C(18) analytical HPLC column enabled the SFE-LC-MS-MS analysis of three polyether ionophore antibiotics in water using a step gradient. A quantitative SFE-LC-MS-MS method has been developed whereby the progress of SFE can be monitored directly on-line such that ionophore recovery profile data from a single water sample can be obtained.

Phase II study of gemcitabine and carboplatin in patients with advanced non-small-cell lung cancer.

Purpose: To evaluate the efficacy and safety of gemcitabine in combination with carboplatin at standard rate or fixed dose rate infusion in patients with advanced non-small-cell lung cancer (NSCLC).

Patients And Methods: In this prospective study, patients with chemonaive advanced NSCLC were randomized to receive gemcitabine at a standard rate (gemcitabine 1,200 mg/m2 over 30 min, the standard arm) or a fixed dose rate (gemcitabine 1,200 mg/m2 over 120 min, the FDR arm) on days 1 and 8 every 3 week cycle. In both treatment arms, carboplatin at AUC of 5 was administered over 4 h following gemcitabine on day 1 of each cycle.