The relationship between ceramide profile and residual inflammatory risk in patients with coronary artery disease: Insights from an prospective study.

Background: Although progress has been made in managing cholesterol, targeting inflammation is essential for further reducing cardiovascular risk, as CVDs remain the leading cause of death globally. This study aimed to explore the association between plasma ceramide levels and residual inflammatory risk in patients with CAD.

Methods: A cross-sectional observational design was adopted using data from a secondary analysis of a multicenter prospective cohort study in China.

[Characteristics of soybean climate potential productivity in frigid region and its response to climate change].

A comprehensive understanding of the evolution of soybean climate potential productivity and its response to climate change in Heilongjiang Province can offer reference and basis for further tapping soybean production potential and realizing stable and high yield of soybean in the frigid region. Based on meteorological data from 80 meteorological stations in Heilongjiang Province from 1961 to 2020, we estimated photosynthesis, light temperature, and climate potential productivity of soybean by the stepwise correction method, examined the spatiotemporal variations by spatial interpolation and statistical analysis methods, and analyzed the impact of changes in climate factors such as radiation, temperature, and precipitation on climate potential productivity. The results showed that during the study period, the average values of photosynthesis potential productivity (), light-temperature potential productivity (), and climate potential productivity () of soybean in Heilongjiang Province were 7533, 6444, and 3515 kg·hm, respectively.

Applicability of the generalized wind profile model over mountainous forests.

The analytical equation based on Monin-Obukhov (M-O) similarity theory (, wind profile equation) has been adopted since 1970s for using in the prediction of wind vertical profile over flat terrains, which is mature and accurate. However, its applicability over complex terrains remains unknown. This applicability signifies the accuracy of the estimations of aerodynamic parameters for the boundary layer of non-flat terrain, such as zero-displacement height () and aerodynamic roughness length (), which will determine the accuracy of frequency correction and source area analysis in calculating carbon, water, and trace gas fluxes based on vorticity covariance method.

A novel [1, 2, 4]triazolo[5,1-b]quinazoline derivative as a fluorescent probe for highly selective detection of Fe ions.

A novel [1, 2, 4]triazolo[5,1-b]quinazoline fluorescent probe () for Fe was developed, featuring with rapid response (< 5 s) and specific selectivity to Fe, low detection limit (1.3 × 10 M), as well as the ability to resist interference of chelating agent (e.g.

A New Pathway for the Synthesis of Ketones from Aldehydes and Sulfonylhydrazones: Is Diazo the Key Intermediate?

A new pathway via a cyclic intermediate for the synthesis of ketones from aldehydes and sulfonylhydrazone derivatives under basic conditions is proposed. Several control experiments were performed along with analysis of the mass spectra and in-situ IR spectra of the reaction mixture. Inspired by the new mechanism, an efficient and scalable method for homologation of aldehydes to ketones was developed.

Demystifying the roles of single metal site and cluster in CO reduction via light and electric dual-responsive polyoxometalate-based metal-organic frameworks.

Photo- or electroreduction of carbon dioxide into highly valued products offers a promising strategy to achieve carbon neutrality. Here, a series of polyoxometalate-based metal-organic frameworks (M-POMOFs) were constructed by metalloporphyrins [tetrakis(4-carboxyphenyl)-porphyrin-M (M-TCPPs)] and reductive POM for photo- and electrocatalytic carbon dioxide reductions (PCR and ECR, respectively), and the mysteries between the roles of single metal site and cluster in catalysis were disclosed. Iron-POMOF exhibited an excellent selectivity (97.

Synthesis of 19-hydroxyprogesterone and insights into the ring-opening mechanism of the 6,19-epoxy bridge.

An efficient and scalable process for the synthesis of 19-hydroxyprogesterone was obtained through seven steps with 34.5% total yield, which is much higher than the process reported in the literature (11.0% total yield).

[Clinical study of age-related sensory innervation of the anterior hard palate].

Objectives: The present study aimed to explore the innervation of the anterior hard palatine and its relationship with individual development stage. Specifically, the effects of anesthesia on patients of different ages were observed, and neurodevelopment in the maxillofacial region was invesitgated. References that are helpful in selecting local anesthesia were provided.

PCR-based screening and phylogenetic analysis of rat pegivirus (RPgV) carried by rodents in China.

Rodent-borne pegiviruses were initially identified in serum samples from desert wood-rats in 2013, and subsequently in serum samples from commensal rats in 2014. However, the prevalence and phylogenetic characteristics of rodent pegiviruses in China are poorly understood. In this study, we screened serum samples collected from wild rats in southern China between 2015 and 2016 for the presence of rat pegivirus (RPgV) by PCR.

[Functions and applications of Multi-Tower Platform of Qingyuan Forest Ecosystem Research Station of Chinese Academy of Sciences].

The relationship between the structure and function of forest ecosystems is the main intere-sts in the research area of forest ecology and management. However, over complex terrains in particular, these studies had been challenged as uneasy tasks due to the limitations in the forest survey and measurement techniques and other supporting technologies. Chinese Academy of Sciences (CAS) funded "Multi-Tower LiDAR/ECFlux Platform for Monitoring the Structure and Function of Secondary Forest Ecosystems" (Multi-Tower Platform, MTP) as a field station network corner-stone research infrastructure project, which was completed by Qingyuan Forest CERN (Chinese Ecosystem Research Network).

[Time-series characteristics of drought and flood in spring soybean growing season and its effect on soybean yield in Heilongjiang Province, China].

Under the background of climate change, the spatial-temporal distribution of precipita-tion in Heilongjiang Province is uneven, and drought and flood frequently change, which is not conducive to the safety of soybean production for the province. To clarify the influence mechanism of drought and flood in the growing season on soybean yield in Heilongjiang Province, we analyzed the time-series characteristics of drought and flood in soybean growing season and its effect on soybean yield in different growth stages, based on data of daily precipitation from 60 meteorological stations during 1961 to 2018 and soybean yield in the same period, with the standardized precipitation index (SPI) as the drought and flood evaluation index. The results showed that, from 1961 to 2018, the influence range of drought in soybean growing season in Heilongjiang Province showed a weak decreasing trend, while that of flood showed a weak increasing trend.

Anthraquinones Extract from Roxb. Root Alleviates Hepatic Injury Induced by Carbon Tetrachloride through Inhibition of Hepatic Oxidative Stress.

In Southwestern China, the root of Roxb. has been employed as a folk medicine for treating various types of hepatitis and jaundice. The purpose of this study was to evaluate the hepatoprotective effects of anthraquinones extract from .

A Review of (Blume) DC. as Traditional Medicinal Plant and Its Therapeutic Potential.

, popularly known as water dropwort, has long been used in various ethnomedical systems in Asia, especially in China, Korean, and Japan, for treating various chronic and acute hepatitis, jaundice, alcohol hangovers, abdominal pain, and inflammatory conditions. The present review aims to provide a general report of the available literature on traditional uses, phytochemical, pharmacological, nutritional, and toxicological data related to the as a potential source of new compounds with biological activities. Considering phytochemical studies, coumarins, flavonoids and flavonoid glycosides, organic acids, and polyphenols were the main classes of compounds identified in the whole plant which were correlated with their biological activities such as hepatoprotective, anti-inflammatory, immune enhancement, ethanol elimination, antioxidant, antiviral, neuroprotective, anti-cancer, anticoagulant, anti-fatigue, hypoglycemic, cardiovascular protection, analgesic, and insecticidal activities.

Synthesis and anti-epileptic activities of novel [1,2,4]-triazolo[1,5-a]pyrimidin-7(4H)-one derivatives.

In this investigation, eight novel 2,5-disubstituted [1,2,4]-triazolo[1,5-a]pyrimidin-7(4H)-one and eight novel 2,5-disubstituted [1,2,4]-triazolo[1,5-a]pyrimidine amine derivatives were synthesized based on the novel marine natural product Essramycin. Their anti-epileptic activities were evaluated by 4-aminopyridine (4-AP)-induced hyper excitability model in primary cultured neocortical neurons. Five compounds with [1,2,4]-triazolo[1,5-a]pyrimidin-7(4H)-one skeleton showed remarkable anti-epileptic activities.

Performance of Hepatitis B Core-Related Antigen Versus Hepatitis B Surface Antigen and Hepatitis B Virus DNA in Predicting HBeAg-positive and HBeAg-negative Chronic Hepatitis.

Background: We examined changes in hepatitis B core-related antigen (HBcrAg) during the four sequential phases of chronic hepatitis B virus (HBV) infection: hepatitis B e antigen (HBeAg)-positive chronic infection (EPCI) and hepatitis (EPCH), followed by HBeAg-negative chronic infection (ENCI) and hepatitis (ENCH). We compared the performance of serum HBcrAg, hepatitis B surface antigen (HBsAg), and HBV DNA in predicting EPCH and ENCH.

Methods: We enrolled 492 consecutive patients: 49 with EPCI, 243 with EPCH, 101 with ENCI, and 99 with ENCH.

[Effects of Conductivity on Performance of a Combined System of Anaerobic Acidification, Forward Osmosis, and a Microbial Fuel Cell].

In this study, a novel combined system for simultaneous recovery of bioelectricity and water from wastewater was developed by integrating anaerobic acidification and a forward osmosis (FO) membrane with a microbial fuel cell (AAFO-MFC). Conductivity was thought to be an important factor affecting the performance of the AAFO-MFC system. Thus, effects of conductivity on the performance of AAFO-MFC system in treating synthetic wastewater were investigated.

[Performance Improvement of Microbial Fuel Cell with Polyaniline Dopped Graphene Anode].

Microbial fuel cell (MFC) technology has potential in recovering bioelectricity from different types of waste, which attracts more and more attention in the field of environment and energy. However, low power density, high cost and low substrate degradation rate, closely associated with anode performance, limit its practical application. In this study, proportional polyaniline (PANI) together with graphene was chosen to obtain the PANI dopped graphene composite.

[Evolution of maize climate productivity and its response to climate change in Heilongjiang Province, China.].

Under the background of climate change, revealing the change trend and spatial diffe-rence of maize climate productivity in-depth and understanding the regularity of maize climatic resources utilization can provide scientific basis for the macro-decision of agricultural production in Heilongjiang Province. Based on the 1981-2014 meteorological data of 72 weather stations and the corresponding maize yield data in Heilongjiang Province, by the methods of step by step revisal, spatial interpolation and linear trend analysis, this paper studied the photosynthetic productivity (PP), light-temperature productivity (LTP), and climatic productivity (CP) of spring maize, and their temporal and spatial variation characteristics, main influencing factors and light energy utilization efficiency, and evaluated the maize climate productivities under different climate scenarios in the future. The results showed that during the study period, the mean PP, LTP and CP in Heilongjiang Province were 26558, 19953, 18742 kg·hm, respectively.

Protective effect of the essential oil of Zanthoxylum myriacanthum var. pubescens against dextran sulfate sodium-induced intestinal inflammation in mice.

Background: Zanthoxylum myriacanthum var. pubescens is an ethnic medicine for digestive disease known as Maqian. A previous report showed that the Maqian fruits essential oil (MQEO) exhibited an NO inhibitory effect on RAW 264.

Role of the calpain on the development of diabetes mellitus and its chronic complications.

Diabetes mellitus (DM) is associated with acute and chronic complications that cause major morbidity and significant mortality. Calpains, a family of Ca(2+)-dependent cytosolic cysteine proteases, can modulate their substrates' structure and function through limited proteolytic activity. Calpain is a ubiquitous calcium-sensitive protease that is essential for normal physiologic function.

Recent advances in understanding the biochemical and molecular mechanism of diabetic retinopathy.

Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes and remains a major cause of preventable blindness among adults at working age. DR involves an abnormal pathology of major retinal cells, including retinal pigment epithelium, microaneurysms, inter-retinal oedema, haemorrhage, exudates (hard exudates) and intraocular neovascularization. Hyperglycemia is the driving force for the development of diabetic retinopathy.

[Land use change dynamics and driving forces of the vulnerable ecological region in northwestern Shanxi Province, China].

By using remote sensing and GIS technology, this paper collected land use information of 1980, 1990, 2000 and 2010 and the relevant statistical data, and analyzed the characteristics of land use change and its driving forces in northwestern Shanxi Province, the typical ecological fragile area. The results showed that there were significant changes in land use patterns in the past 30 years. During 1980-1990, 1990-2000 and 2000-2010 periods, the area of farmland decreased continuously, while the areas of grassland and woodland experienced increase-decrease-increase and decrease-increase-decrease patterns of change, respectively.

The presence of hydrogenotrophic methanogens in the inoculum improves methane gas production in microbial electrolysis cells.

High current densities in microbial electrolysis cells (MECs) result from the predominance of various Geobacter species on the anode, but it is not known if archaeal communities similarly converge to one specific genus. MECs were examined here on the basis of maximum methane production and current density relative to the inoculum community structure. We used anaerobic digester (AD) sludge dominated by acetoclastic Methanosaeta, and an anaerobic bog sediment where hydrogenotrophic methanogens were detected.

[Effect of Cu2+ on the power output of dual-chamber microbial fuel cell].

After addition of Cu2+ into the anodic and/or cathodic chamber, the effect of Cu2+ on the internal resistance and its distribution, power output and coulombic efficiency of dual-chamber microbial fuel cell (MFC) was investigated in this manuscript with the aid of analyzing the distribution of copper speciation. It could provide helpful information for correlative research on treatment of copper-containing wastewater by MFC. It showed that the addition of 10 mg x L(-1) Cu2+ into the anodic chamber inhibited the microbial activity, and increased the anodic activation resistance as well as the apparent internal resistance, consequently reduced the power output and coulombic efficiency of the system.