Publications by authors named "Xitong Zuo"
The hematopoietic activity of EPO is unfavorable to the treatment of bleomycin-induced pulmonary fibrosis in mice.
Biochem Biophys Res Commun
December 2024
Article Synopsis
- Erythropoietin (EPO) primarily promotes blood cell production and helps alleviate anemia, but it also has various protective effects against inflammation and cell death.
- While high doses of EPO show potential in reducing symptoms of pulmonary fibrosis in mice, this treatment does not improve overall health outcomes like weight loss or mortality rates.
- Additionally, EPO treatment leads to increased red blood cell levels but is also associated with adverse effects like thrombosis in the lungs, suggesting that its benefits in lung fibrosis may not outweigh the risks.