The Causal Relationship Between Choline Metabolites and Acute Acalculous Cholecystitis: Identifying as Colocalized Gene.

Background: Acute acalculous cholecystitis (AAC) is a type of cholecystitis with high mortality rate while its pathogenesis remains complex. Choline is one of the essential nutrients and is related to several diseases. This study aimed to explore the causal relationship between choline metabolites and AAC and its potential mechanisms.