Publications by authors named "Xiqin Ruan"
Article Synopsis
- Endometrial carcinoma (EC) is a common and serious gynecological cancer, but its causes and mechanisms are not fully understood; this study investigates genetic factors linked to EC.
- Researchers used various analyses to develop a prognostic risk signature and identified key genes like RNF144A that are significantly involved in EC and could serve as potential biomarkers for treatment.
- RNF144A was found to be a particularly important hub gene, with its expression levels negatively correlating with cancer severity, and its overexpression linked to increased cell growth and migration in EC.
RACGAP1 (Rac GTPase-activating protein 1) is correlated with tumor aggressiveness and poor prognosis, but the role of RACGAP1 in cervical cancer has not been fully reported. Analysis of RACGAP1 expression data in cervical cancer from the Cancer Genome Atlas (TCGA) database was carried out by GEPIA and UALCAN websites. In addition, the UALCAN database was used to identify the RACGAP1 positively correlated genes, which were used for the enrichment analysis.
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