Publications by authors named "Xiping Xu"

In order to solve the issues arising from collisions, this paper proposes a network flow method combined with skeleton information for multiple tracking. In the intra-track stage, non-colliding are identified and associated as trajectory fragments based on their motion and positional information, and colliding are then segmented based on an improved skeleton algorithm and matched as trajectory fragments. Subsequently, the trajectory fragments are employed as vertices to construct a network flow model.

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In order to address the issue of tracking errors of collision Caenorhabditis elegans, this research proposes an improved particle filter tracking method integrated with cultural algorithm. The particle filter algorithm is enhanced through the integration of the sine cosine algorithm, thereby facilitating uninterrupted tracking of the target C. elegans.

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Echinacoside (ECH), one of the most representative phenylethanoid glycosides (PhGs), has considerable neuroprotective effects and is an effective ingredient in numerous commercial drugs. Here, we elucidate the complete ECH biosynthetic pathway in the medicinal plant Cistanche tubulosa. In total, 14 related genes are cloned and functionally characterized.

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Assessing the quality of corn seeds necessitates evaluating their water, fat, protein, and starch content. This study integrates hyperspectral imaging technology with chemometric analysis techniques to achieve non-invasive and rapid detection of multiple key components in corn seeds. Hyperspectral images of the embryo surface of maize seeds were collected within the wavelength range of 1100~2498 nm.

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Background: The association between S-adenosylhomocysteine (SAH) and stroke has not been confirmed due to the specialized equipment and time requirements necessary for S-adenosylhomocysteine testing. We aimed to explore the association between SAH and stroke.

Methods: A nested, case-control study drawn from the China Stroke Primary Prevention Trial of rural adults with hypertension, including 557 first stroke cases and 557 matched controls was conducted.

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Enzymatic malonylation of natural glycosides provides a promising alternative method for drug-like malonylated glycosides supply. However, the catalytic potential and structural basis of plant malonyltransferase are far from being fully elucidated. This work identified a new malonyltransferase CtMaT1 from It displayed unprecedented mono- and/or di-malonylation activity toward diverse glucosides with different aglycons.

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Although the association between persistent hypertension and the compromise of both micro- and macro-circulatory functions is well recognized, a significant gap in quantitative investigations exploring the interplay between microvascular and macrovascular injuries still exists. In this study, the authors looked into the relationship between brachial-ankle pulse wave velocity (baPWV) and hypertensive retinopathy in treated hypertensive adults. The authors conducted a cross-sectional study of treated hypertensive patients with the last follow-up data from the China Stoke Primary Prevention Trial (CSPPT) in 2013.

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To objectively quantify the level of visual interference induced by lasers, we developed a biomimetic optical system designed to emulate human vision. This system is based on an optical model of the eye and synthetic imaging principles, allowing it to generate biomimetic optical images that closely mimic human visual perception. Upon exposure to a 532 nm laser, biomimetic optical images were captured under various ambient lighting conditions.

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Background And Purpose: The enzyme methylenetetrahydrofolate reductase (MTHFR) plays a crucial role in directing folate species towards nucleotide synthesis or DNA methylation. The MTHFR polymorphisms C677T and A1298C have been linked to cancer susceptibility, but the evidence supporting this association has been equivocal. To investigate the individual and joint associations between MTHFR C677T, A1298C, and digestive system cancer in a Chinese hypertensive population, we conducted a population-based case-control study involving 751 digestive system cancer cases and one-to-one matched controls from the China H-type Hypertension Registry Study (CHHRS).

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The moisture content of corn seeds is a crucial indicator for evaluating seed quality and is also a fundamental aspect of grain testing. In this experiment, 80 corn samples of various varieties were selected and their moisture content was determined using the direct drying method. The hyperspectral imaging system was employed to capture the spectral images of corn seeds within the wavelength range of 1100-2498 nm.

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Background: The prospective relationship between plasma vitamin E levels and proteinuria remains uncertain. We aimed to evaluate the association between baseline plasma vitamin E levels and the development of proteinuria and examine any possible effect modifiers in patients with hypertension.

Methods: This was a post hoc analysis of the renal sub-study of the China Stroke Primary Prevention Trial (CSPPT).

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When the workpiece surface exhibits strong reflectivity, it becomes challenging to obtain accurate key measurements using non-contact, visual measurement techniques due to poor image quality. In this paper, we propose a high-precision measurement method shaft diameter based on an enhanced quality stripe image. By capturing two stripe images with different exposure times, we leverage their different characteristics.

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The thermal deformation fitting result of an optical surface is an important factor that affects the reliability of optical-mechanical-thermal integrated analysis. The traditional numerical methods are challenging to balance fitting accuracy and efficiency, especially the insufficient ability to deal with high-order Zernike polynomials. In this Letter, we innovatively proposed an opto-thermal deformation fitting method based on a neural network and a transfer learning to overcome shortcomings of numerical methods.

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Background: Iron is an essential element for organismal health but excessive iron is potentially toxic. However, few observational studies link plasma iron (PI) concentrations and cancer risk, and the results are inconsistent.

Objective: This study aimed to explore the associations of PI concentrations with cancer risk in Chinese adults with hypertension.

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Aiming to solve the problem of color distortion and loss of detail information in most dehazing algorithms, an end-to-end image dehazing network based on multi-scale feature enhancement is proposed. Firstly, the feature extraction enhancement module is used to capture the detailed information of hazy images and expand the receptive field. Secondly, the channel attention mechanism and pixel attention mechanism of the feature fusion enhancement module are used to dynamically adjust the weights of different channels and pixels.

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Background: There is growing concern regarding elevated levels of circulating unmetabolized folic acid (UMFA) due to excessive intake of folic acid (FA). However, no randomized clinical trial has been conducted to examine the FA-UMFA dose-response relationship.

Objective: This study aimed to investigate the FA-UMFA dose-response relationship in Chinese adults with hypertension and elevated homocysteine (H-type hypertension), a population with clear clinical indication for FA treatment.

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Objective: Single-pill amlodipine besylate (AML) plus losartan (LOS) has been used to treat inadequately controlled hypertension after antihypertensive monotherapy; however, relevant data in China are limited. This study aimed to compare the efficacy and safety of single-pill AML/LOS and LOS alone in Chinese patients with inadequately controlled hypertension after LOS treatment.

Methods: In this multicenter, double-blind, randomized, controlled phase III clinical trial, patients with inadequately controlled hypertension after 4 weeks of LOS treatment were randomized to receive daily single-pill AML/LOS (5/100 mg, AML/LOS group,  = 154) or LOS (100 mg, LOS group,  = 153) tablets for 8 weeks.

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Background And Objectives: High homocysteine levels are associated with increased risk of hypertension and stroke. Homocysteine is metabolized by the methylenetetrahydrofolate reductase (). We aimed to investigate the levels of homocysteine and their association with hypertension, stroke, and antihypertensive medication usage in patients with different C677T genotypes.

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Malnutrition is a common comorbidity among patients with cancer. However, no nutrition-screening tool has been recognized in this population. A quick and easy screening tool for nutrition with high sensitivity and easy-to-use is needed.

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Purpose: We investigated the association between albuminuria and hypertensive retinopathy (HR) in hypertensive adults.

Methods: This was a cross-sectional subgroup analysis of data from the China Stroke Primary Prevention Trial. We enrolled 2,964 hypertensive adults in this study.

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The Aquila Optimizer (AO) is a new bio-inspired meta-heuristic algorithm inspired by Aquila's hunting behavior. Adaptive Aquila Optimizer Combining Niche Thought with Dispersed Chaotic Swarm (NCAAO) is proposed to address the problem that although the Aquila Optimizer (AO) has a strong global exploration capability, it has an insufficient local exploitation capability and a slow convergence rate. First, to improve the diversity of populations in the algorithm and the uniformity of distribution in the search space, DLCS chaotic mapping is used to generate the initial populations so that the algorithm is in a better exploration state.

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Background: The prospective association between plasma Se and stroke risk remains inconclusive. The relationship between Se and ischemic stroke among a low circulating Se status population deserves more attention, especially for Chinese people who were a high-risk group for Se deficiency.

Objective: The relationship between plasma Se concentration and ischemic stroke risk in a large-scale Chinese community-based population and any potential effect modifiers were investigated.

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Background: The kidney has the highest level of selenium (Se) in the body, but the role of plasma Se in chronic kidney disease is uncertain.

Objective: We aimed to investigate the longitudinal association between baseline plasma Se and renal function decline in adults with hypertension and to explore possible effect modifiers.

Methods: This was a post hoc analysis of 935 men and women with hypertension aged 40 to 75 years from a folic-acid intervention trial (the China Stroke Primary Prevention Trial) in China.

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Background: Evidence from epidemiologic studies has been limited and inconsistent regarding the role of serum calcium in stroke incidence risk. We aimed to evaluate the association between serum albumin-corrected calcium and the risk of the first stroke in the Chinese community-dwelling population.

Methods: The study sample population was drawn from the "H-type Hypertension and Stroke Prevention and Control Project.

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Background: Serine plays a key role in numerous cellular processes, the levels and metabolism is therefore of critical importance. However, few data are available to illustrate the association of serine with long-term health effects, especially, the predictive value for long-term mortality.

Objective: This study was conducted to evaluate the relationship between serum serine levels and all-cause mortality in general hypertensive patients in a longitudinal cohort, and to examine the potential effect modifiers.

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