Microglia play a crucial role in the activation of immune defense mechanism as the resident macrophages in the central nervous system (CNS). Microglia can eliminate damaged neurons, plaques, and other infectious agents. Triggering receptor expressed on myeloid cell-2 (TREM-2) speculates to be beneficial in preventing inflammation-induced bystander damage of neurons.
View Article and Find Full Text PDFObjective: To examine the associations between inflammatory markers, coagulation and fibrinolysis parameters, and microvascular complications in 182 Chinese patients with type 2 diabetes mellitus (T2DM) who sought treatment at a large hospital in Zhejiang province, China.
Methods: We investigated the relationships of blood inflammatory markers with hemostatic markers in 87 patients with T2DM who did not have complications and 95 patients with T2DM who had microvascular complications.
Results: C-reactive protein (CRP) and interleukin-6 (IL-6) were significantly correlated with fibrinogen, thrombin-antithrombin III complex (TAT III), plasminogen activator inhibitor-1 (PAI-1), von Willebrand factor (vWF), and coagulation factors (F) VII in patients with T2DM who had microvascular complications (P <.
Background: Serum sialic acid (SA) is an acute phase response marker. Additionally, it is an independent risk factor for atherosclerotic disease and is higher in patients with type 2 diabetes mellitus (T2DM). The objective of this study was to determine the association of SA with blood coagulation and fibrinolysis in T2DM patients.
View Article and Find Full Text PDFLipid metabolic disturbances are related to many diseases, such as obesity, diabetes, and certain cancers. Notably, lipid metabolic disturbances have been reported to be a risk factor for colorectal cancer. Nuclear receptors act as ligand-dependent transcription regulators and play key roles in the regulation of body lipid metabolism and the development of many cancers.
View Article and Find Full Text PDFObjective: A systematical investigation on the distribution of wild germplasm of Regonia fimbristipula in Dinghu District, Zhaoqing City, Guangdong Province was conducted at 8 sites.
Methods: Field quadrat survey method was carried out.
Results: Begonia fimbristipula had obvious phenotypical plasticity showing three phenotypes with red, green and bicolor leaf, respectively.
Objective: To study the effect of different plant growth substance and activated charcoal on rooting in culture seedling of Begonia fimbristpula on Dinghushan mountain.
Methods: Tissue culture single factor experiment method was used.
Results: NAA 0.