Assessment of glycemic susceptibility across multiple urological and reproductive disorders.

Objective: To test the glycemic susceptibility in three urological cancers and eight urological/reproductive diseases using the Mendelian randomization (MR) method.

Materials And Methods: Two-sample MR was applied to investigate the causal role of three glycemic traits (type II diabetes, fasting glucose and glycated hemoglobin (HbA1c)) in eleven urological/reproductive diseases (kidney cancer, bladder cancer, prostate cancer, kidney/ureter stone, urinary incontinence, benign prostatic hyperplasia, erectile dysfunction, female infertility, male infertility, abnormal spermatozoa and polycystic ovary syndrome). Further multivariate MR (MVMR) and mediating analysis were performed to investigate the associations.

Mechanism of carbon nanotube growth in expanded graphite via catalytic pyrolysis reaction using carbores P as a carbon source.

Carbon nanotubes (CNTs) had potential applications in energy conversion and storage devices, and it could be prepared by expanded graphite loaded with catalyst at high temperature, however, the mechanism of carbon nanotube growth in expanded graphite need further confirmation. In this work, carbon nanotubes' growth in expanded graphite (EG) were prepared via catalytic pyrolysis reaction using carbores P as a carbon source and Co(NO)•6HO as a catalyst. The results of X-ray diffraction (XRD), scanning electron microscope (SEM) and energy dispersive X-ray spectroscope (EDS) indicated the carbon nanotubes could generate in, EG with the presence of carbores P as a carbon source and cobalt nitrate as a catalyst.

Nb/N Co-Doped Layered Perovskite SrTiO: Preparation and Enhanced Photocatalytic Degradation Tetracycline under Visible Light.

Sr2TiO4 is a promising photocatalyst for antibiotic degradation in wastewater. The photocatalytic performance of pristine Sr2TiO4 is limited to its wide bandgap, especially under visible light. Doping is an effective strategy to enhance photocatalytic performance.

Comparison of intrarenal pelvic pressure and postoperative fever between standard- and mini-tract percutaneous nephrolithotomy: a systematic review and meta-analysis of randomized controlled trials.

Background: High intrarenal pelvic pressure (IPP) induces systemic absorption of irrigation fluid containing bacteria or endotoxins, which is associated with postoperative fever (POF) and even urosepsis. The emphasis of this meta-analysis lies in comparison of IPP and POF between mini-tract percutaneous nephrolithotomy (MPCNL) and standard-tract percutaneous nephrolithotomy (SPCNL).

Methods: Eligible randomized controlled trials (RCTs) were identified from electronic databases from inception to November 2019.

Correction to: Self assembly and controlled drug release of a nano-laminated graphite carbon nitride/methotrexate complex.

The original version of this article unfortunately contained a mistake. In the Abstract section the sentence "Furthermore, the drug release mechanism was investigated by kinetic models and a first-order relationship was concluded, which indicated that the drug release is a simple diffusion process cohydroxyapatite/methotrexate complexntrolled by gradient drug concentration." was wrong.

Cyclic hydrostatic pressure promotes uroplakin expression in human urothelial cells through activation of ERK1/2 signaling.

Objectives: To investigate the effect of cyclic hydrostatic pressure on the expression of uroplakins and the role of extracellular regulated protein kinases 1/2 (ERK1/2) in the hydrostatic pressure-induced uroplakin expression of human urothelial cells (UCs).

Methods: Human UCs were seeded into a cell culture flask and subjected to cyclic hydrodynamic pressures for 24 h. Pressure parameters were set as follows: static, 100 cm HO, 200 cm HO and 300 cm HO pressure.

Self assembly and controlled drug release of a nano-laminated graphite carbon nitride/methotrexate complex.

In this study, g-CN/methotrexate (g-CN/MTX) nanohybrids were obtained via a self assembly method. XRD and TEM demonstrated that bulk g-CN had been stripped into thin nanosheets with size range of 150-250 nm. FTIR investigation indicated that the self assembly of the hybrid was attributed to the hydrogen bond between g-CN nanosheets and MTX molecules.

Knockout of OsNramp5 using the CRISPR/Cas9 system produces low Cd-accumulating indica rice without compromising yield.

Rice grain with excessive cadmium (Cd) is a major source of dietary Cd intake and a serious threat to health for people who consume rice as a staple food. The development of elite rice cultivars with consistently low Cd content is challenging for conventional breeding approaches, and new strategies urgently need to be developed. Here, we report the development of new indica rice lines with low Cd accumulation and no transgenes by knocking out the metal transporter gene OsNramp5 using CRISPR/Cas9 system.

Morphology effect of nano-hydroxyapatite as a drug carrier of methotrexate.

In this study, morphology effect of nano-hydroxyapatite as a drug carrier was investigated for the first time. Hydroxyapatite/methotrexate (HAp/MTX) hybrids with different morphologies were successfully prepared in situ using polyethylene glycol (PEG) as a template. SEM, TEM, XRD and FTIR results confirmed that the hybrids of different morphologies (laminated, rod-like and spherical) with similar phase composition and functional groups were obtained by changing the preparation parameters.