Publications by authors named "Xiongchang Tan"
Article Synopsis
- Gut microbiota dysbiosis contributes to post-stroke depression (PSD) and is linked to neuron damage and decreased connectivity in the hippocampus; inulin may offer protective effects through the microbiome-gut-brain axis.
- A study utilized the GEO database to explore gene expression changes after inulin intake and validated findings in a rat model, noting behavioral changes and gut microbiota composition alterations.
- Results indicated that inulin enhanced the mitogen-activated protein kinase pathway, increased beneficial gut bacteria, elevated insulin-like growth factor 1, boosted activity levels in rats, and reduced body weight, suggesting a therapeutic potential for inulin in managing PSD.
