Schisandrol A mitigated voriconazole-induced liver injury in mice through regulation of farnesoid X receptor-mediated bile acid metabolism.

Schisandrol A has been previously used to mitigate hepatotoxicity. However, the effects of schisandrol A on voriconazole-induced hepatic injury have not been investigated. In this study, we aimed to explore the effects of schisandrol A on voriconazole-induced hepatic injury in mice, as well as to elucidate the underlying mechanism.