[Biotoxicology and biodynamics of silica nanoparticle].

Objective: To investigate the toxicology and biodynamics of silica nanoparticle.

Methods: The silica nanoparticles were injected into mice through tail vein, and the mice were amphimixised, the urine was collected in different time, variations of pathology in organs and tissues of the mice were detected. At the same time, the silica nanoparticles' distribution in the tissues was observed through electron microscope.