Publications by authors named "Xiong-feng Li"

Background: Osteosarcoma is the most prevalent malignant bone tumour with a poor prognosis. Shikonin (SHK) is derived from the traditional Chinese medicine Lithospermum that has been extensively studied for its notable anti-tumour effects, including for osteosarcoma. However, its application has certain limitations.

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Objective: To investigate the method and clinical effect of modified Chevron osteotomy of the distal end of the first metatarsal in the treatment of moderate and severe hallux valgus.

Methods: From January 2015 to January 2019, 28 patients(30 feet) with moderate and severe hallux valgus were treated with modified Chevron osteotomy combined with lateral soft tissue release of the first metatarsophalangeal joint, including 2 males (2 feet) and 26 females (28 feet). The age ranged from 35 to 74 (57.

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Objective: To explore clinical effect of modified Chevron osteotomy combined with lateral tissue loosening for the treatment of mild-moderate hallux valgus through internal signal approach.

Methods: From July 2015 to June 2016, 26 patients with mild-moderate hallux valgus treated with modified Chevron osteotomy combined with lateral tissue loosening through internal signal approach, including 2 males and 24 females aged from 45 to 65 years old with an average of(54.6±4.

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Article Synopsis
  • Non-small cell lung cancer (NSCLC) is responsible for 85% of lung cancer deaths globally, and the impact of heat shock protein 90B1 (HSP90B1) and DNA damage-inducible transcript 3 (DDIT3) on NSCLC has not been fully explored.
  • A study examined 143 NSCLC tissue samples and found that high expression of HSP90B1 was linked to advanced clinical stages and lymph node metastasis, while DDIT3 was only correlated with lymph node metastasis.
  • Importantly, high levels of HSP90B1 were associated with poorer overall survival and disease-free survival, indicating it could serve as an independent prognostic factor in NSCLC.
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Group II and III metabolic glutamate receptors (mGluRs) are responsible for the glutamate-mediated postsynaptic excitation of neurons. Previous pharmacological evidences show that activation of mGluR7 could inhibit nociceptive reception. However, the distribution and expression patterns of mGluR7 after peripheral injury remain unclear.

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Objective: To study the effects of Bushen Zhuangjin Decoction (BZD) containing serum on the apoptosis of chondrocytes induced by mechanics stimulus.

Methods: The BZD containing serum was extracted. The chondrocyte nutritive media was divided into 3 groups, i.

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Objective: To evaluate the clinical effects of total hip arthroplasty (THA) for Crowe type IV developmental dysplasia of the hip (DDH) and analyze perioperative complications.

Methods: From March 2000 to March 2010, 19 patients (23 hips, of them, 4 patients with bilateral hips) with Crowe type IV DDH underwent THA. There were 5 males and 14 females, with average age of 61.

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Objective: To explore the internal fixation selection and the operative method of Pilon fracture.

Methods: From Aug. 2004 to Aug.

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Objective: To typing of tibial plateau fracture based on spiral CT reconstruction and to explore effect of the typing method for treatment.

Methods: A hundred and twenty-six cases with tibial plateau fracture (male 95, female 31, age from 23 to 58 years old), the fractures were classified based on reconstruction image of spiral CT. Including central compression type in 13 cases, split type in 8, split compression type in 79, comminution type in 26.

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