Publications by authors named "Xiong-bin Lu"
Article Synopsis
- Colorectal cancer (CRC) is typically diagnosed at an advanced stage, leading to limited treatment success due to therapy resistance mechanisms.
- Resistance to chemo- and targeted therapies hinders overall survival and necessitates the exploration of new treatment options.
- Promising therapies such as the α-amanitin antibody-drug conjugate show potential, alongside ongoing developments to enhance responses to checkpoint inhibitors in CRC patients, particularly those with specific tumor characteristics.
[The effects of culture supernatant of bladder tumor cells on formation and function of dendritic cells].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
March 2005
Aim: To explore the effects of culture supernatant of bladder tumor cell lines BIU-87 on the development and function of peripheral blood mononuclear cell (PBMC)-derived dendritic cells.
Methods: The culture supernatant of BIU-87 cells was collected and used as the conditional culture medium for PBMC-derived DCs culture in experiment group. Normal cultured DCs were used as control group.
Localization of PS9 in Rice Ragged Stunt Oryzavirus and Its Role in Virus Transmission by Brown Planthopper.
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)
January 1999
Article Synopsis
- A cDNA of the rice ragged stunt oryzavirus (RRSV) was created to express its protein PS9 in E. coli, resulting in a purified 38kD polypeptide after cleavage.
- Using antiserum raised against the fusion protein, gold immuno-labelling experiments indicated that this 38kD polypeptide is a key protein in the virus spikes.
- Virus transmission tests with brown planthoppers showed that the presence of PS9 inhibited virus transmission, suggesting that spike proteins are crucial for viral infection.
cDNA Cloning of the Guinea Pig Growth Hormone Receptor.
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)
January 2000
cDNA cloning and 1 899 bp sequence of growth hormone receptor (GHR) from guinea pig liver are described. The guinea pig GHR consists of 610 amino acids. The structural feature and homology comparison of guinea pig GHR are also reported.
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