Publications by authors named "Xiong Feng Pan"
Objects: Taurine exhibits protective effects in the context of cardiovascular pathophysiology. A range of evidence suggests that hypertension activates inflammatory responses and oxidative stress in the paraventricular nucleus (PVN), elevating the arterial tone and sympathetic activity, while it induces gut-brain axis dysfunction in the context of hypertension. However, the mechanism underlying taurine's anti-hypertensive effects via the gut-brain axis remains unclear.
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- The objective of the study was to summarize existing research on genetic variants linked to nonalcoholic fatty liver disease (NAFLD).
- A systematic search of literature from various databases yielded 399 studies, leading to the identification of 465 genetic variants across many genes.
- The meta-analysis found 11 significant genetic variants associated with NAFLD, providing moderate to strong evidence for six variants in five genes that could enhance understanding of NAFLD risk.