Harnessing antimicrobial peptides in endodontics.

Endodontic therapy includes various procedures such as vital pulp therapy, root canal treatment and retreatment, surgical endodontic treatment and regenerative endodontic procedures. Disinfection and tissue repair are crucial for the success of these therapies, necessitating the development of therapeutics that can effectively target microbiota, eliminate biofilms, modulate inflammation and promote tissue repair. However, no current endodontic agents can achieve these goals.

BNN/TiO nanocomposite system-modified dental flow resins and the mechanism of the enhancement of mechanical and antibacterial properties.

Robust and antibacterial dental resins are essential for repairing the shape and function of the teeth. However, an ingenious way to achieve a synergistic enhancement of these two properties is still lacking. In this work, guided by molecular dynamics (MD) calculations, a boron nitride nanosheet (BNN)/titanium dioxide (TiO) nanocomposite system was synthesized and used to modify the dental flow resin to enhance its mechanical and antimicrobial properties.