Palladium-Catalyzed Annulation Reaction of Bay-Iodobiphenyls with Maleimides to Access 9,10-Phenanthrenedicarboximides.

A palladium-catalyzed annulation reaction of bay-iodobiphenyls with maleimides was developed. This approach allows for the efficient synthesis of a variety of 9,10-phenanthrenedicarboximides, particularly polyalkoxy-substituted 9,10-phenanthrenedicarboximides with potential liquid-crystalline properties. Research findings indicate that the resulting product, -hexyl-2,3,6,7-tetrakis(hexyloxy)-9,10-phenanthrenedicarboximide, exhibits promising, good liquid-crystalline properties.

SMARCA4-Deficient Undifferentiated Gallbladder Cancer: A Case Report and Review of the Literature.

Nonsense mutations or inactivation of (BRG1) are associated with the histological manifestations of many undifferentiated tumors in humans. However, the relationship between mutations and undifferentiated gallbladder cancer needs to be further elucidated. SMARCA4-deficient undifferentiated gallbladder cancer is a rare and highly malignant tumor.

Clinicopathologic and Genomic Features of Invasive Stratified Mucin-producing Carcinoma of the Uterine Cervix Coexisting With High-grade Squamous Intraepithelial Lesion.

Invasive stratified mucin-producing carcinoma (ISMC) is a specific type of adenocarcinoma of the cervix, which is associated with human papillomavirus infection and often coexists with other types of carcinomas. However, given its rarity, understanding of this disease remains insufficient. We present a unique case of ISMC of the cervix coexisting with a high-grade squamous intraepithelial lesion (HSIL).

High-quality genome assembly and annotation of strain Cc878 using Oxford Nanopore long-read sequencing.

As a noteworthy biocontrol fungus, currently lacks a high-quality reference genome. Here, we present the first high-quality genome assembly of strain Cc878 achieved through Oxford Nanopore Long-Read sequencing. The nuclear genome of Cc878 was assembled into four contigs, totaling 59.

Palladium-Catalyzed Annulative π-Extension of Bay-Iodinated Triphenylenes to Access Polycyclic Aromatic Compounds.

A palladium-catalyzed annulative π-extension reaction of bay-iodinated triphenylenes with aryl iodides/-chloroaromatic carboxylic acids was developed. This approach enabled the synthesis of diverse polycyclic aromatic compounds, including dibenzo[,]tetracenes, azadibenzo[,]tetracenes, and tribenzo[,,]coronenes. Initial studies indicate that the resulting product, 2,3,8,9,14,15-hexakis(decyloxy)tribenzo[,,]coronene, exhibits good liquid-crystalline properties.

Adaptive advantages of restorative RNA editing in fungi for resolving survival-reproduction trade-offs.

RNA editing in various organisms commonly restores RNA sequences to their ancestral state, but its adaptive advantages are debated. In fungi, restorative editing corrects premature stop codons in pseudogenes specifically during sexual reproduction. We characterized 71 pseudogenes and their restorative editing in , demonstrating that restorative editing of 16 pseudogenes is crucial for germ tissue development in fruiting bodies.