FeO@Ag@Pt nanoparticles with multienzyme like activity for total antioxidant capacity assay.

A simple and reliable total antioxidant capacity (TAC) assay is essential for food safety evaluation and human health monitoring. Herein, a trimetallic nanozyme (FeO@Ag@Pt) was synthesized and exhibited OXD-, POD- and SOD-like activities, which could generate a synergistic catalytic system. FeO@Ag@Pt can catalyze oxygen to produce various reactive oxygen intermediates, and the endogenous product HO could be captured and further dissociated efficiently into •OH, due to its strong substrate binding affinity.