Publications by authors named "Xinyan Y Lu"
Article Synopsis
- * Pediatric NMZL, while rare, has distinct characteristics including male predominance, localized stage I disease, and lower relapse rates compared to its adult counterpart.
- * A case study highlights an unusual pediatric NMZL instance with advanced disease, persistent symptoms post-therapy, atypical immunophenotype markers, and unique chromosomal changes like monosomy 20.
Background: Precursor B acute lymphoblastic leukemia (B-ALL) is the most common cancer in children and overall, has an excellent prognosis. However, the Philadelphia chromosome translocation (Ph+), t(9;22)(q34;q11), is present in a small subset of patients and confers poor outcomes. CD25 (IL-2 receptor alpha chain) expression has been associated with Ph+ B-ALL in adults, but no similar study has been performed in pediatric B-ALL.
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