Publications by authors named "Xinyan Jin"

Purpose: This study aimed to investigate the usefulness of ultrasound-guided core-needle biopsy (US-CNB) for diagnosing type 1 AIP and evaluate the radiological outcomes following steroid therapy.

Materials And Methods: From January 2017 to June 2023, patients with pathology results containing "lymphoplasmacytic infiltration" and "fibrosis" were enrolled. The detection rate of level 1 histology by International Consensus Diagnostic Criteria (ICDC) and the contribution of US-CNB were assessed.

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Shengmai San (SMS) is a traditional Chinese medicine formula used for supplementing and and can mitigate symptoms related to malignant arrhythmia and heart failure. This systematic review aimed at exploring the effectiveness and safety of SMS for viral myocarditis (VMC). Eight databases from their inception to June 2023 were searched to identified randomized controlled trials (RCTs) focusing on SMS for VMC.

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Article Synopsis
  • Plant fibers play a crucial role in enhancing the physical strength and properties of reconstituted tobacco, affecting its overall mechanical performance.
  • The study analyzed how different types of plant fibers and their beating degrees influenced various mechanical properties, such as tensile strength and thermal conductivity.
  • It was found that softwood fibers provided the best improvement in physical properties at a specific beating degree, leading to significant increases in tensile strength and other key metrics for reconstituted tobacco.
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Understanding the puff-by-puff delivery mechanisms of key components of heated tobacco products is critical to developing product designs. This study investigates the puff-by-puff release patterns of key components in Natural Smoke Cigarettes (NSCs), which are designed to deliver nicotine without combustion by reducing oxygen content, utilizing a 30-s puff interval, a 2-s puff duration, and a 55 mL puff volume to simulate realistic smoking conditions. By establishing models to analyze the variation of nicotine, glycerol, 1,2-propylene glycol (PG), and water in different functional sections of the cigarette under controlled smoking conditions.

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Ethnopharmacological Relevance: Vascular endothelial dysfunction (VED) is recognized as a key triggering diabetic vascular complications. Danggui Liuhuang Decoction (DGLHD) has shown potential in mitigating these complications. However, the clinical efficacy of DGLHD in enhancing endothelial function, as well as the molecular mechanisms underlying its alleviation of Type 2 Diabetes-Related Vascular Endothelial Dysfunction (T2DM-VED), remains insufficiently understood.

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Chinese medicated bath is one of the external therapies in Traditional Chinese Medicine (TCM), which has been widely used clinically. The "International Standard of Traditional Chinese Medicine Techniques: The Operating Specifications for Chinese Medicated Bath" is drawn up by the Beijing University of Chinese Medicine Third Affiliated Hospital and Beijing University of Chinese Medicine Xiamen Hospital in collaboration with domestic TCM universities and hospitals. The specification includes definition, operating process, points for attention and contraindications.

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Antiretroviral regimens for human immunodeficiency virus (HIV) infection have continuously evolved; however, antiretrovirals can cause severe adverse reactions. Two-drug regimen therapy can decrease lifetime cumulative drug exposure and long-term toxicities associated with multiple antiretrovirals. The preferred 2-drug regimen constitutes dolutegravir (DTG) and lamivudine (3TC).

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  • The study investigated the efficacy and safety of Shufeng Jiedu (SFJD) capsules for managing mild to moderate COVID-19 symptoms through a randomized, double-blind, placebo-controlled trial conducted in China from May to December 2022.
  • A total of 407 participants completed the trial, with those taking SFJD experiencing faster symptom relief, with a median time of 7 days compared to 8 days for the placebo group.
  • The SFJD group also showed significant reductions in fever and headache symptoms, and no serious adverse events occurred during the trial.
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  • Post-viral olfactory dysfunction (PVOD) is a common symptom of long COVID that lacks effective treatments, prompting a systematic review of traditional Chinese medicine (TCM) for potential solutions.
  • The review included various studies evaluating TCM, specifically acupuncture and acupoint injection, which demonstrated some effectiveness for PVOD, although the overall quality of evidence was deemed low.
  • While some trials showed positive outcomes, more rigorous and well-designed studies are necessary to confirm the effectiveness and safety of acupuncture and acupoint injection in treating PVOD.
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  • Chronic fatigue is a key symptom of long COVID, and this study investigates how Traditional, Complementary, and Integrative Medicine (TCIM) can help alleviate this fatigue.* -
  • Thirteen randomized controlled trials (RCTs) with a total of 1,632 participants were analyzed, revealing that some herbal treatments, like Bufei Huoxue capsules and Ludangshen liquid, showed potential in reducing fatigue levels.* -
  • However, the overall evidence is considered low to very low in quality due to bias concerns, indicating a need for more extensive and higher-quality studies to validate these findings.*
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Aims: This study aimed to synthesize the evidence of the comparative effectiveness and safety of () preparations combined with renin-angiotensin system inhibitors (RASi) for diabetic kidney disease (DKD).

Methods: Eight databases were searched from their inception to May 2023. Systematic reviews (SRs) of preparations combined with RASi for DKD were identified.

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Background: : During the coronavirus disease (COVID-19) pandemic, health care workers (HCWs) have faced a heightened risk of infection. Preventative measures are critical to mitigate the spread of COVID-19 and protect HCWs. Traditional Chinese medicine (TCM) has been recommended to prevent and treat COVID-19 in China.

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Background: Zhuang-Gu-Fang (ZGF) has been proved to treat osteoporosis in ovariectomized rats by increasing osteogenic related factors Leptin, Ghrelin and Peptide YY(PYY). However, the mechanism of ZGF in the treatment of diabetic osteoporosis (DOP) remains unclear. The aim of this study was to explore the therapeutic effect of ZGF on DOP and its potential molecular mechanism.

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Introduction: Dandelion (Pugongying) is one of the most frequently used Chinese herbs for treating lactational mastitis (LM). Pugongying granules, a patented medication primarily comprised of dandelion extract, have been approved by CFDA for LM treatment in China. The aims of this study were to investigate the etiology of LM and the mechanism by which Pugongying granules decrease LM symptoms, with a particular focus on the microbial communities found in breastmilk.

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Article Synopsis
  • * A total of 13 systematic reviews (SRs) covering 265 studies with over 33,000 participants were analyzed, focusing on acupoint stimulation, although most studies were of low quality and many included non-randomized trials.
  • * The findings indicated that TCM external interventions were significantly more effective than placebo for maintaining smoking abstinence over 6 months to 1 year, and they also helped reduce nicotine withdrawal symptoms without serious adverse events reported.
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Approximately 59 % of patients with breast cancer with one or two sentinel lymph nodes (1-2 SLN) macrometastases do not benefit from axillary lymph node dissection (ALND), which may also incur morbidities. It is necessary to evaluate the association between various clinicopathological characteristics and non-sentinel lymph node metastases (non-SLNM) in patients with breast cancer with 1-2 SLN macrometastases, and determine whether they 1-2 should avoid ALND. Eight electronic literature databases (PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure, Chinese Scientific Journal, Wanfang, and Chinese Biomedical Literature) were searched from their inception to June 30, 2023, and two reviewers independently extracted the data and assessed the risk of bias.

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This study aimed to investigate the impact of β-glucan (QBG) concentrations and molecular weights (MWs) on rice starch (RS). With the increasing concentrations and MWs, the pasting properties and gelatinization enthalpy of RS/QBG suspension decreasing was observed by using rheometer and differential thermal scanning analysis, respectively, which was consistent with the results of X-ray diffraction. In Infrared spectrum, QBG combined with leached amylose via hydrogen bonds, thus preventing the reaggregation of RS particles and inhibiting the short-term retrogradation of RS.

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  • Developed an economical magnetic photocatalyst using discarded waste rice noodle (WRN) and iron oxide scale (IOS) by converting WRN into carbon quantum dots (CQDs) and calcining IOS for iron oxide (FeO).
  • The synthesized CQDs/FeO composite improved electron-hole pair separation, resulting in effective photodegradation of pollutants like methylene blue (99.30% degradation in 480 min) and tetracycline, while maintaining high degradation efficiency across multiple cycles.
  • Exhibited strong magnetism (34.7 emu/g), allowing for easy recovery and promising large-scale applications in photocatalytic water purification.
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Background: As ultrasound-guided percutaneous liver biopsy (PLB) has become a standard and important method in the management of liver disease in our country, a periodical audit of the major complications is needed.

Aim: To determine the annual incidence of major complications following ultrasound-guided PLB and to identify variables that are significantly associated with an increased risk of major complications.

Methods: A total of 1857 consecutive cases of PLB were included in our hospital from January 2021 to December 2021.

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Preclinical studies have proven that nanosecond pulsed electric field (nsPEF) ablation can be a safe and effective treatment for humans with unresectable liver cancer that are ineligible for thermal ablation. The concomitant activation of antitumor immunity by nsPEF can also potentially prevent tumor recurrence. However, whether nsPEF exhibits similar efficacy in a clinical setting remains to be investigated.

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Ginsenoside Rg1 (Rg1) has been demonstrated to have antidiabetic and antiosteoporotic activities. The aim of this study was to investigate the protective effect of Rg1 against diabetic osteoporosis and the underlying mechanism. , we found that Rg1 increased the number of osteoprogenitors and alleviated high glucose (HG) induced apoptosis of osteoprogenitors by MTT assays and flow cytometry.

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In recent year, many deep learning have been playing an important role in the detection of cancers. This study aimed to real-timely differentiate a pancreatic cancer (PC) or a non-pancreatic cancer (NPC) lesion endoscopic ultrasonography (EUS) image. A total of 1213 EUS images from 157 patients (99 male, 58 female) with pancreatic disease were used for training, validation and test groups.

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To provide a low-cost photocatalyst and new methodology for the utilization of waste rice noodle (WRN), a carbon quantum dots/zinc oxide (CQDs/ZnO) composite using WRN as the raw material was synthesized and characterized. The CQDs/ZnO composite based on WRN exhibited a highly efficient photocatalytic degradation effect on various organic pollutants and could be a good alternative for commercial ZnO. For methylene blue, the CQDs/ZnO composite showed a good degradation rate of 99.

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Backgrounds: Percutaneous ultrasound (US) and endoscopic ultrasound (EUS)-guided pancreatic biopsies are widely accepted in the diagnosis of pancreatic diseases. Studies comparing the diagnostic performance of US- and EUS-guided pancreatic biopsies are lacking. This study aimed to evaluate and compare the diagnostic yields of US- and EUS-guided pancreatic biopsies and identify the risk factors for inconclusive biopsies.

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In this work, a cost-effective wax was synthesized from waste cooking oil (WCO), and its properties including melting point, color, hardness, combustion performance and micro-morphology were tested and analyzed. The obtained results showed that the epoxy waste cooking oil had lighter color, higher melting point and hardness than that of original WCO, which could be used as wax. Moreover, introducing stearic acid further improved the performances of WCO-based wax.

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