Dipropyl phthalate induces craniofacial chondrogenic defects in zebrafish embryos.

Dipropyl phthalate (DPRP), a plasticizer commonly utilized in the plastics industry, has been identified in food and the environment and has the potential to present a hazard to human health and the environment. In this study, the first comprehensive evaluation of DPRP-induced craniofacial chondrogenic defects was conducted using a zebrafish model. Zebrafish embryos were exposed to 1, 2, and 4 mg/L DPRP from 6 to 96 h post-fertilization.

Sub-nanopores enabling optimized ion storage performance of carbon cathodes for Zn-ion hybrid supercapacitors.

Aqueous Zn-ion hybrid supercapacitors (ZHSs) are attracting significant attention as a promising electrochemical energy storage system. However, carbon cathodes of ZHSs exhibit unsatisfactory ion storage performance due to the large size of hydrated Zn-ions (e.g.

Negatively Charged Hydrophobic Carbon Nano-Onion Interfacial Layer Enabling High-Rate and Ultralong-Life Zn-Based Energy Storage.

Zn-based electrochemical energy storage (EES) systems are attracting more attention, whereas their large-scale application is restricted by the dendrite and parasitic reaction-caused unstable Zn anodes. Herein, a negatively charged hydrophobic carbon nano-onion (CNO) interfacial layer is proposed to realize ultrastable and high-rate Zn anodes, enabling high-performance Zn-based EES. For the CNO interfacial layer, its hydrophobicity not only blocks active water but also reduces the Zn desolvation barrier, and meanwhile, the negatively-charged CNO nanoparticles adsorb Zn and repel SO to homogenize Zn flux, accelerate Zn desolvation and suppress the self-corrosion of Zn anodes.

Functional Ultrathin Separators Proactively Stabilizing Zinc Anodes for Zinc-Based Energy Storage.

Ultrathin separators are indispensable to high-energy-density zinc-ion batteries (ZIBs), but their easy failure caused by zinc dendrites poses a great challenge. Herein, 23 µm-thick functional ultrathin separators (FUSs), realizing superb electrochemical stability of zinc anodes and outstanding long-term durability of ultrathin separators, are reported. In the FUSs, an ultrathin but mechanically strong nanoporous membrane substrate benefits fast and flux-homogenized Zn transport, while a metal-organic framework (MOF)-derived C/Cu nanocomposite decoration layer provides rich low-barrier zinc nucleation sites, thereby synergistically stabilizing zinc anodes to inhibit zinc dendrites and dendrite-caused separator failure.

Preparation and performance characteristics of spider venom peptide nanocapsules.

Background: ω-hexatoxin-Hvn1b is an insecticidal toxin produced by the Tasmanian funnel-web spider (Hadronyche venenata), that can be exploited for development of novel bioinsecticides. Due to its larger size and low membrane permeability, this toxin usually has a slower mode of action compared to conventional small molecule insecticides. Nanoscale materials have unique optical, electrical, mechanical and biological properties, and show great application prospects for pesticide delivery.

Synthesis of carbon dots@FeO and their photocatalytic degradation properties to hexaconazole.

The CD@FeO photocatalysts were synthesized via hydrothermal synthesis method. The CD@FeO particles were synthesized using FeO as the core and using citric acid and ethylenediamine as a raw material, which were heated to 200 °C for 4 h. The synthesized fluorescent CD@FeO was characterized by HR-TEM, IR and fluorescence spectrophotometer.

Efficacy and Pharmacological Mechanism of -Based Formulas Combined With Chemotherapy for Ovarian Cancer: A Integrated Systems Pharmacology Study.

Previous studies have shown that -based formulas combined with chemotherapy can improve the quality of life of ovarian cancer patients. However, the results are still controversial. We systematically searched the literature from eight databases to evaluate the efficacy and safety of -based formulas in combination with paclitaxel-carboplatin in treating ovarian cancer (OC).

Can Elderly Patients With Pancreatic Cancer Gain Survival Advantages Through More Radical Surgeries? A SEER-Based Analysis.

Background And Aims: In recent years, the best treatment method for pancreatic cancer in elderly patients has remained controversial. Surgery is the main treatment modality for pancreatic cancer. This study aimed to determine whether elderly patients with pancreatic cancer can gain survival advantages through more active and radical surgical treatment and evaluate the best treatment method and potential prognostic factors.

The preparation of prochloraz pH-responsive nanocapsules by the Pickering emulsion polymerization method and the study of their performance.

In this work, prochloraz pH-responsive nanocapsules were developed by the Pickering emulsion polymerization method with isophorone diisocyanate (IPDI) as the reaction monomer and nano FeO particle-branched polyethyleneimine (PEI) as the reaction monomer and surfactant. The physical and chemical properties and sustained release properties were determined by a transmission electron microscope (TEM), field emission transmission electron microscope (FETEM), atomic force microscope (AFM), laser particle size analyzer, Fourier transform infrared spectrometer, and contact angle tester. The results indicated that the prochloraz nanocapsules were spherical, the average particle size was about 100 nm, and the encapsulation efficiency and loading rates were 86% and 30%, respectively.

Preparation of cyflumetofen nanocapsules and study on the controlled release performance and its field efficacy.

Background: In this study, 5% cyflumetofen nanocapsules were prepared by interfacial polymerization with isophorone diisocyanate and polyethylene glycol as the reaction monomer, and tristyrylphenol polyoxyethylene ether (601-P) as the emulsifier. The physical, chemical and sustained release properties of cyflumetofen nanocapsules were characterized using scanning electron microscopy, field emission scanning electron microscopy, laser particle size analysis, Fourier transform infrared spectroscopy, contact angles testing and high-performance liquid chromatography.

Results: The results indicated that cyflumetofen nanocapsules were spherical, with an average particle size of 100 nm, and an encapsulation efficiency and loading rate of 86% and 32%, respectively.