Publications by authors named "Xinxin Lu"

Two nanosheets of BiNbOCl were successfully synthesized for photocatalytic conversion of CO into solar fuel, featuring differently exposed (001) and (201) facets. The exposure of these specific facets facilitates C-C coupling to generate ethanol, and (201) facet typically accelerates this process.

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In this article, we report a male patient infected with HIV presenting with cryptococcal meningitis, pneumonia, and bloodstream infection, along with intestinal obstruction and gastrointestinal bleeding. Cerebrospinal fluid and bloodstream analyses revealed the presence of Cryptococcus neoformans complex. The isolated strain was sequenced and was found to belong to Cryptococcus neoformans var.

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Bismuth oxide (BiVO4) is considered one of the most promising semiconductors for photoelectrochemical (PEC) water splitting due to its highly theoretical photocurrent of 7.5 mA cm-2. However, its sluggish kinetics and severe photocorrosion still hinder the real application of a large-area BiVO4 photoanode.

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Article Synopsis
  • - Diabetic kidney disease (DKD) affects about 40% of diabetic patients, leading to severe health issues like end-stage renal disease and significant economic costs globally; symptoms include protein leakage in urine and increased cardiovascular risk.
  • - Current treatments for DKD primarily manage hypertension and blood sugar levels but do not cure the disease or tackle its root causes; medications like SGLT2 inhibitors and ACE inhibitors are commonly used.
  • - Recent research emphasizes mitochondrial dysfunction as a critical factor in DKD progression, suggesting that targeting mitochondrial health could improve treatment outcomes by reducing oxidative stress and promoting better energy production in kidney cells.
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Sucrose transporter (SUT) plays essential roles in plant growth and development, as well as responses to diverse abiotic stresses. However, limited information about the function of SUT was available in pineapple, an important tropical fruit crop with crassulacean acid metabolism. Here, four AcSUT genes were identified in pineapple genome, and divided into three clades according to the phylogenetic analysis.

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  • Tratt (RRT) is known for its distinctive aroma and high nutritional content, with a study identifying 99 volatile compounds in its juice across four different elevations.
  • Of these compounds, 37 showed aroma activity, with 29 being significant contributors based on their high OAVs (Odor Activity Values).
  • The research identified 18 key aroma compounds through tests and noted that the lowest elevation area, Longli, produced the most aromatic RRT.
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  • The study examined the link between weekend outdoor activity duration (WCOD) and myopia rates among students in China, surveying over 100 schools in six cities.
  • Findings revealed that students with myopia spent less time outdoors on weekends than those without myopia, with a significant negative relationship between WCOD and myopia prevalence, particularly notable with 2-4 hours of WCOD.
  • The research suggests that increasing outdoor time on weekends may help decrease the risk of myopia, indicating that outdoor exposure is important for eye health in students.
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This study aimed to investigate the molecular epidemiological characteristics and drug sensitivity of Cryptococcus from HIV-infected patients and their relationship with patients' prognosis. Seventy-six strains were collected and identified to the species level by matrix-assisted laser desorption ionization-time of flight mass spectrometry, confirmed by internal transcribed spacer sequencing. Multi-locus sequence typing was used for the typing of Cryptococcus, and its antifungal susceptibility was tested using FUNGUS 3.

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  • Cardiac pacemakers are essential for treating arrhythmias, but traditional devices can cause issues like heart damage and infection risks due to their rigid components and reliance on batteries.
  • A new wireless, battery-free bioelectronic device has been developed, featuring flexible and stretchable hydrogel electrodes that mimic heart tissue, enabling better ECG recording and pacing.
  • This innovative device has shown effective performance for 31 days post-implantation in rats and has the potential for customizable pacing in live studies, significantly improving future cardiac treatment options.
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  • Neoadjuvant immunochemotherapy (NICT) shows better efficacy than traditional neoadjuvant chemotherapy (NCT) for non-small-cell lung cancer (NSCLC), as demonstrated by higher rates of pathological complete response (pCR) and event-free survival (EFS).
  • The combination of toripalimab with chemotherapy achieved the best surgical resection rates and pCR, especially effective in patients with low PD-L1 expression or squamous cell pathology.
  • While NICT is effective, longer treatment cycles can lead to increased adverse events; specifically, the combination of nivolumab with chemotherapy has the worst safety profile compared to other combinations.
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  • - Chlamydia trachomatis infections are on the rise, with an additional 9 million cases annually, and can lead to adult inclusive conjunctivitis (AIC), which often goes underdiagnosed due to its nonspecific symptoms.
  • - Researchers developed six C. trachomatis culture cell lines, particularly the MA104 N*V line, which showed reduced levels of key immune response proteins and the highest bacterial growth post-infection, making it suitable for further study.
  • - In a study with 20 AIC patients, 7 tested positive for C. trachomatis, and the researchers successfully isolated the pathogen, identifying various serovars, which can enhance future diagnostics, treatments, and vaccine development
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Background: Cryptococcosis is an invasive infection that commonly affects immunosuppressed individuals, especially patients with HIV infection. Cryptococcal infection in HIV-infected patients should be considered a major health concern because it is associated with high morbidity and mortality rates. In this study, we aimed to evaluate the clinical characteristics and prognostic factors of cryptococcal infections in human immunodeficiency virus (HIV)-infected patients to facilitate effective clinical management and improve patient outcomes.

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  • Microbial keratitis (MK) is a major cause of blindness worldwide, and this study assessed the costs incurred by 602 MK patients treated at a Beijing hospital from 2021 to 2023.* -
  • The average treatment cost was approximately USD 1646.8, with the highest expenses reported for Acanthamoeba keratitis (AK) patients, particularly in ophthalmic exams and lab tests.* -
  • The study found that treatment costs significantly increased with MK severity and were notably higher for patients who delayed seeking care, emphasizing the need for prompt diagnosis and treatment.*
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CO reduction photocatalysts are favorable for obtaining renewable energy. Enriched active sites and effective photogenerated-carriers separation are keys for improving CO photo-reduction. A thulium (Tm) single atom tailoring strategy introducing carbon vacancies in porous tubular graphitic carbon nitride (g-CN) surpassing the ever-reported g-CN based photocatalysts, with 199.

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Diabetes, a multifaceted metabolic disorder, poses a significant global health burden with its increasing prevalence and associated complications, such as diabetic nephropathy, diabetic retinopathy, diabetic cardiomyopathy, and diabetic angiopathy. Recent studies have highlighted the intricate interplay between N-methyladenosine (mA) and non-coding RNAs (ncRNAs) in key pathways implicated in these diabetes complications, like cell apoptosis, oxidative stress, and inflammation. Thus, understanding the mechanistic insights into how mA dysregulation impacts the expression and function of ncRNAs opens new avenues for therapeutic interventions targeting the mA-ncRNAs axis in diabetes complications.

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Implantable cardiac pacemakers are crucial therapeutic tools for managing various cardiac conditions. For effective pacing, electrodes should exhibit flexibility, deformability, biocompatibility, and high conductivity/capacitance. Laser-induced graphene (LIG) shows promise due to its exceptional electrical and electrochemical properties.

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Purpose: The clinical manifestations of pyogenic liver abscess (PLA) vary between patients with and without diabetes mellitus (DM). However, the relationship between PLA and the gut microbiome remains unknown. This study analyzed the composition of gut microbiota in PLA patients with and without DM and healthy controls (HCs) with the goal of identifying potential reasons for the observed variations in clinical manifestations.

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During outdoor work in April 2022, a 48-year-old man was stabbed by a tree branch and underwent intraocular foreign body extraction and repair of the scleral wound with sutures and amniotic membrane graft at a local hospital. Steroid therapy with prednisone was prescribed after a diagnosis of uveitis. Vitrectomy was performed in June 2023; a fungal culture was positive, and ITS sequencing identified the organism as Paradictyoarthrinium diffractum.

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Rationale: The triangular electrode linear ion trap with asymmetric geometry has been reported to possess a high ion unidirectional ejection efficiency and a reasonable mass resolution. To further improve its performance, a double resonant excitation method involving a dipolar and a quadrupolar resonant excitation was applied here.

Methods: The dipolar excitation method was carried out by applying a supplementary alternating voltage out of phase to one pair of the electrodes, whereas the quadrupolar excitation (QE) method was carried out by adding a supplementary alternating voltage in phase to another pair of electrodes.

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Aqueous Sn-air batteries are attracting a great deal of interest in recent years due to the ultra-high safety, low cost, dendrite-free and highly reversible Sn anode. However, the slurry oxygen reduction/evolution reaction (ORR/OER) kinetics on the air cathodes seriously affect the Sn-air battery performances. Although various advanced catalysts have been developed, the charge overpotentials (~1000 mV) of these Sn-air batteries are still not satisfactory.

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Volatile secondary metabolites of plants interact with environments heavily. In this work, characteristic components of Michelia yunnanensis essential oils (EOs) were isolated, purified and identified by column chromatography, GC-MS and NMR. Leaves of M.

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The effective flow of electrons through bulk electrodes is crucial for achieving high-performance batteries, although the poor conductivity of homocyclic sulfur molecules results in high barriers against the passage of electrons through electrode structures. This phenomenon causes incomplete reactions and the formation of metastable products. To enhance the performance of the electrode, it is important to place substitutable electrification units to accelerate the cleavage of sulfur molecules and increase the selectivity of stable products during charging and discharging.

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