Exhaled breath analysis using on-line preconcentration mass spectrometry for gastric cancer diagnosis.

Breath volatile biomarkers are capable of distinguishing patients with various cancers. However, high throughput analytical technology is a prerequisite to a large-cohort study intended to discover reliable breath biomarkers for cancer diagnosis. Single-photon ionization (SPI) is a universal ionization technology, and SPI-mass spectrometry (SPI-MS) shows a remarkable advantage in the comprehensive detection of volatile organic compounds (VOCs), in particular, nonpolar compounds.

Numerical Study on the Gas-Solid Flow in a Spouted Bed Installed with a Controllable Nozzle and a Swirling Flow Generator.

The swirling flow technology is adopted on a nozzle of the spouted bed in order to enhance the radial movement of the particles. The hydrodynamic characteristics in a spouted bed with a swirling flow generator installed on the nozzle are numerically investigated based on the two-fluid model (TFM). The traditional spouted bed and spouted bed with an integral swirling blade nozzle (ISBN) are simulated and analyzed.

Experimental Study on Gas-Solid Flow in the Spouted Bed under Longitudinal Vortex Effect.

To strengthen the particles radial movement and mixing, the longitudinal vortex generator of a sphere was adopted in the spouted bed in this study. To find the influence of the longitudinal vortex and particle properties on axial and radial velocities of particles in a 152 mm-diametered spouted bed, particle image velocimetry (PIV) was employed. The experimental results show that the addition of the longitudinal vortex generator caused the vortex movement of high-speed gas and induced a considerable secondary fine vortex in the cross section of the spouted bed, and the existence of longitudinal vortex significantly improved the radial velocity of particles, compared with that of the conventional spouted bed.