Publications by authors named "Xinwei Lei"

Objectives: To explore the different involvement patterns of the knee "synovio-entheseal complex (SEC)" on MRI in patients with spondyloarthritis (SPA), rheumatoid arthritis (RA), and osteoarthritis (OA).

Methods: This study retrospectively included 120 patients (male:female, 55:65) with a mean age of 39.20 years diagnosed with SPA (n = 40), RA (n = 40), and OA (n = 40) at the First Central Hospital of Tianjin between January 2020 and May 2022.

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Objective: To determine the distribution and diagnostic value of peripheral enthesitis detected by whole-body MRI (WBMRI) in axial spondyloarthritis (axSpA) diagnosis, and to determine the value of the peripheral enthesitis score in axSpA assessment.

Methods: Sixty axSpA patients [mean age of 33.2 (24.

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Objectives: Fat metaplasia in an erosion cavity, also known as backfill, is an essential intermediary in new bone formation in axial spondyloarthritis (axSpA) patients; however, the predictors of backfill progression are unknown. This longitudinal study aimed to assess the predictors of backfill progression in axSpA patients on magnetic resonance imaging (MRI).

Methods: Clinical and MRI data were collected at baseline and follow-up in 52 axSpA patients.

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Background: Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatic disease affecting the spine and sacroiliac joints. To investigate whether there are differences in inflammatory and chronic structural damages, as assessed by a semiquantitative MRI scoring method, between non-radiographic axial spondyloarthritis (nr-axSpA) and ankylosing spondylitis (AS) patients with active inflammation at baseline, and to evaluate the treatment response in these patients after 3 months of tumor necrosis factor-alpha (TNF-α) inhibitor treatment.

Methods: Fifty-eight axSpA patients with active inflammation were included in the study.

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Facet tropism and orientation are thought to be associated with lumbar disc herniation (LDH), but the relationship is not well established. Moreover, the effect of facet joint on LDH has not been outlined in young patients. The objective of this study was to investigate the associations of facet joint tropism and orientation with LDH in young patients (18-35 years) by computed tomography (CT).

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Objectives: To investigate the clinical value of dynamic contrast-enhanced MRI (DCE-MRI) and laboratory indexes in predicting conversion from undifferentiated arthritis (UA) to rheumatoid arthritis (RA).

Methods: A total 81 DMARD-naive UA patients were studied. 37 cases were ultimately diagnosed as RA, 32 cases were diagnosed as other types of arthritis, and the remaining cases were still UA during the 1-year follow-up.

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Purpose: The aim of this study was to assess the value of apparent diffusion coefficient (ADC) in distinguishing synovitis from joint fluid and bone erosion from cysts.

Methods: Twenty-eight patients with suspected rheumatoid arthritis underwent diffusion-weighted imaging and pre- and post-contrast-enhanced magnetic resonance imaging. The mean ADC values were compared between synovitis and joint effusion and between bone erosion and cyst.

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Objective: To evaluate the clinical value of dual-energy CT(DECT) in the detection of green-coloured voxels in toenails in patients with gout using DECT.

Methods: A total of 53 patients with gout could be included in the study composed of 45 men and 8 women, and 33 individuals without gout were regarded as control group. There were no significant differences in gender and age between two groups.

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Objective: To construct different 3-D finite element resurfacing arthroplasty of hip models and to explore the biomechanics influences of cement mantle varying in thickness on stress distribution and stressshielding in the proximal femur following hip resurfacing arthroplasty (RSAH), and evaluate the changes of bone mineral density in femur after RSAH , in order to find the adaptive methods to stem fixing.

Methods: A comparative study was carrie out in patients who underwent RSAH. The bone mineral Density of the proximal femur was measured through dual energy X-ray absorptiomenty of the four zone at post-operation and unoperation 6 months.

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