Isolated Mitochondrial Transplantation as a Novel Treatment for Corneal Chemical Burns.

Purpose: This study aimed to investigate the therapeutic potential of isolated mitochondrial transplantation for the restoration of corneal surface injury in mice after corneal chemical burn.

Methods: Mitochondria were isolated from mesenchymal stem cells via ultracentrifugation, followed by an assessment of their purity and viability. The internalization of mitochondria by human corneal epithelial cells was tracked using a live fluorescence imaging system.

Acupuncture treatment of restless legs syndrome: a randomized clinical controlled study protocol based on PET-CT and fMRI.

Introduction: Restless legs syndrome (RLS) is a sensorimotor disorder of the nervous system that is mainly characterized by nighttime leg discomfort and can be accompanied by significant anxiety, depression, and other mood disorders. RLS seriously affects the quality of life. Clinical studies have confirmed that acupuncture can alleviate the clinical symptoms of RLS.

The effect of pressing needle therapy on depression, anxiety, and sleep for patients in convalescence from COVID-19.

Objective: To evaluate the effect of pressing needle therapy on depression, anxiety, and sleep in patients recovering from COVID-19, and to provide a more effective and convenient treatment for the sequelae of COVID-19.

Methods: A total of 136 patients recovering from COVID-19 were randomized into a treatment group (68 cases) and a control group (68 cases, with one case dropping out). The treatment group received pressing needle therapy, while the control group received sham pressing needle therapy, three times a week for 4 weeks.

Apolipoprotein E epsilon4 allele is associated with better performance language and visual memory in spinocerebellar ataxia type 3.

Background: The regulatory role of the apolipoprotein E (APOE) ε4 allele in the clinical manifestations of spinocerebellar ataxia type 3 (SCA3) remains unclear. This study aimed to evaluate the impact of the APOE ε4 allele on cognitive and motor functions in SCA3 patients.

Methods: This study included 281 unrelated SCA3 patients and 182 controls.

Microvasculature and trabecular bone in beagle proximal femur: Microstructural insights.

Background: Avascular necrosis of femoral head and malunion are frequent post-operative complications of femoral neck fractures. To optimize surgical techniques, this study aims to provide a microstructural understanding of intraosseous microvasculature and the trabecular bone of the femoral head and neck.

Study Design: This anatomical study analyzed twenty-eight femora from fourteen cadaveric beagles.

CYP7B1 deficiency impairs myeloid cell activation in autoimmune disease of the central nervous system.

Dysregulation of cholesterol metabolism underlies neurodegenerative disease and is increasingly implicated in neuroinflammatory diseases, such as multiple sclerosis (MS). Cytochrome P450 family 7 subfamily B member 1 (CYP7B1) is a key enzyme in alternative cholesterol metabolism. A recessive mutation in the gene CYP7B1 is known to cause a neurodegenerative disease, hereditary spastic paraplegia type 5 and oxysterol accumulation.

A Vision/Inertial Navigation/Global Navigation Satellite Integrated System for Relative and Absolute Localization in Land Vehicles.

This paper presents an enhanced ground vehicle localization method designed to address the challenges associated with state estimation for autonomous vehicles operating in diverse environments. The focus is specifically on the precise localization of position and orientation in both local and global coordinate systems. The proposed approach integrates local estimates generated by existing visual-inertial odometry (VIO) methods into global position information obtained from the Global Navigation Satellite System (GNSS).

Electroacupuncture for hot flashes in early postmenopause: A study protocol for a randomized sham-controlled trial.

Introduction: Many early postmenopausal women experience hot flashes (HFs). Electroacupuncture (EA) is a safe and effective therapy for menopause-related symptoms. However, there are few rigorous clinical trials on this topic.

Smart-Data-Glove-Based Gesture Recognition for Amphibious Communication.

This study has designed and developed a smart data glove based on five-channel flexible capacitive stretch sensors and a six-axis inertial measurement unit (IMU) to recognize 25 static hand gestures and ten dynamic hand gestures for amphibious communication. The five-channel flexible capacitive sensors are fabricated on a glove to capture finger motion data in order to recognize static hand gestures and integrated with six-axis IMU data to recognize dynamic gestures. This study also proposes a novel amphibious hierarchical gesture recognition (AHGR) model.

Effect of Electroacupuncture Versus Cognitive Behavioral Therapy for Perimenopausal Insomnia: Protocol for a Noninferiority Randomized Controlled Trial.

Background: Perimenopausal insomnia (PMI) has a high global incidence, which is common in middle-aged women and is more severe than nonmenopausal insomnia. Effective treatments with fewer side effects and more consistent repeatable results are needed. Acupuncture, a therapy based on traditional Chinese medicine, is safe and may be effective for PMI.

Cognitive impairment associated with cerebellar volume loss in spinocerebellar ataxia type 3.

Background: Many neuroscience and neurology studies have forced a reconsideration of the traditional motor-related scope of cerebellar function, which has now expanded to include various cognitive functions. Spinocerebellar ataxia type 3 (SCA3; the most common hereditary ataxia) is neuropathologically characterized by cerebellar atrophy and frequently presents with cognitive impairment.

Objective: To characterize cognitive impairment in SCA3 and investigate the cerebellum-cognition associations.

Lacunes are associated with late-stage multiple sclerosis comorbidities.

Multiple sclerosis (MS) is a condition that affects the veins and small blood vessels. Previous research suggests that individuals with MS have an increased risk of vascular events and higher mortality rates. However, the relationship between MS and cerebral small vessel disease (CSVD) remains uncertain.

[ acupuncture for perimenopausal insomnia of kidney- deficiency: a randomized controlled trial].

Objective: To observe the clinical efficacy of acupuncture (acupuncture for tonifying kidney and calming spirit ) in treating perimenopausal insomnia (PMI) of kidney- deficiency.

Methods: A total of 72 patients with PMI of kidney- deficiency were randomized into an observation group (36 cases, 1 case dropped off) and a control group (36 cases, 1 case dropped off). Acupuncture was applied at Baihui (GV 20) and bilateral Shenshu (BL 23), Taixi (KI 3), Anmian (Extra) in the observation group, while sham acupuncture of shallow needling at non-acupoints was applied in the control group.

Species Richness of Papilionidae Butterflies (Lepidoptera: Papilionoidea) in the Hengduan Mountains and Its Future Shifts under Climate Change.

The family of Papilionidae (Lepidoptera: Papilionoidea) is a group of butterflies with high ecological and conservation value. The Hengduan Mountains (HMDs) in Southwest China is an important diversity centre for these butterflies. However, the spatial distribution pattern and the climate vulnerability of Papilionidae butterflies in the HDMs remain unknown to date.

[Acupuncture for delayed sleep-wake phase disorder: a randomized controlled trial].

Objective: To observe the clinical effect of acupuncture for delayed sleep-wake phase disorder (DSWPD).

Methods: A total of 84 patients with DSWPD were randomized into an observation group (42 cases, 2 cases dropped off) and a control group (42 cases, 3 cases dropped off). On the basis of sleep hygiene education, acupuncture was applied at Shenmai (BL 62), Zhaohai (KI 6), Hegu (LI 4), Taichong (LR 3), Zusanli (ST 36) and Sanyinjiao (SP 6) in the observation group, while placebo acupuncture was applied at the same acupoints in the control group.

Knowledge Mapping Analysis of International Research on Acupuncture for Low Back Pain Using Bibliometrics.

Objective: Acupuncture has made recommendations to relieve low back pain (LBP) in a few guidelines. However, few articles focused on the papers published before, which may reflect the trend of study, main researchers, reciprocal collaboration, and other information in this field. In this study, we utilize the bibliometric analysis methods to objectively analyze the current trend and research hotspots about this field, aiming to provide a foundation and reference for future study.

Effects of Electroacupuncture on Sleep via the Dopamine System of the HPA Axis in Rats after Cage Change.

Background: Insomnia is often related to stressful events. The hypothalamus-pituitary-adrenal (HPA) axis is related to stress, and dopamine (DA) and DA receptors are involved in the regulation of HPA axis. Electroacupuncture (EA) can improve sleep in individuals with insomnia, but the mechanism is unclear.

Biological Impact and Enzyme Activities of (Lepidoptera: Noctuidae) in Response to Synergistic Action of Matrine and .

Matrine, a naturally occurring heterocyclic compound, has been shown to enhance the pathogenicity of the entomopathogenic fungus against . In the current study, the biological impacts and synergism activities of these two agents on nutritional efficiency and antioxidant enzymes in were explored. Our results showed a high antifeedant activity of and matrine on .

Acupuncture for insomnia with short sleep duration: protocol for a randomised controlled trial.

Introduction: Insomnia with short sleep duration has a more serious negative impact on patient health. The existing literature suggests that medication therapy is more effective for this phenotype of insomnia compared with cognitive-behavioural therapy. However, the potential side effects of hypnotic medications hinder their clinical application.

Matrine Enhances the Pathogenicity of Against (Lepidoptera: Noctuidae).

The repetitive application of pesticides at high doses against Fabricius has resulted in development of pesticide resistance and harmful effects to the natural environmental. Hence, finding alternate pest control strategies, such as entomopathogenic fungi or their application in combination with other natural chemicals, is of great importance to solve the abovementioned problems. This study presents the toxic effects of and matrine (individual or in combination with each other) against tobacco cutworm ().

Optimizing Top- Multiclass SVM via Semismooth Newton Algorithm.

Top- performance has recently received increasing attention in large data categories. Advances, like a top- multiclass support vector machine (SVM), have consistently improved the top- accuracy. However, the key ingredient in the state-of-the-art optimization scheme based upon stochastic dual coordinate ascent relies on the sorting method, which yields complexity.