Publications by authors named "Xintong Xiao"

Lipid oxidation-induced imbalance in the redox system is one of the key causative factors leading to accelerated aging in living organisms and related diseases. Online sampling and analysis of the heterogeneous ozonolysis kinetics of lipid aerosols are highly important in revealing the oxidation-driven aging process of lipids. In this paper, an online detection method based on atmospheric pressure photoionization combined with ultrahigh resolution mass spectrometry (APPI-HRMS) is developed for real-time analysis of the heterogeneous reactions between lipid particles (oleic acid and squalene) and ozone.

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Online analysis of the composition and evolution of complex oligomeric intermediates in biomass degradation is highly desirable to elucidate the mechanism of bond cleavage and study the effect of conditions on the selective conversion of feedstocks. However, harsh reaction conditions and complicated conversion systems pose tremendous challenges for conventional, state-of-the-art analytical techniques. Herein, we introduce a continuous and rapid compositional analysis strategy coupling a high-pressure flow-through reactor with online high-resolution mass spectrometry, which enables the molecular-level characterization of most biomass-related products throughout the conversion for over 2 h.

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The centrosome linker serves to hold the duplicated centrosomes together until they separate in late G2/early mitosis. Precisely how the linker is assembled remains an open question. In this study, we identify Cep44 as a novel component of the linker in human cells.

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