[Therapeutic effect of chlorhexidine combined with mechanical debridement on peri-implantitis and its influence on patients' SF-36 score].

Purpose: To study the effect of chlorhexidine combined with mechanical debridement on peri-implant inflammation and the influence on SF-36 score of patients.

Methods: One hundred patients with peri-implantitis admitted to Zhejiang Provincial People's Hospital from January 2015 to January 2019 were selected and randomly divided into control group and combined group with 50 cases in each group according to random number table method.Patients in both groups were treated with mechanical debridement, and patients in the combined group were gargled with chlorhexidine gargle apart from mechanical debridement.

The Inhibition of MicroRNA-139-5p Promoted Osteoporosis of Bone Marrow-Derived Mesenchymal Stem Cells by Targeting Wnt/Beta-Catenin Signaling Pathway by NOTCH1.

We investigated the therapeutic effects of microRNA-139-5p in relation to osteoporosis of bone marrow-derived mesenchymal stem cell (BMSCs) and its underlying mechanisms. In this study we used a dexamethasone-induced in vivo model of osteoporosis and BMSCs were used for the in vitro model. Real-time quantitative polymerase chain reaction (RT-PCR) and gene chip were used to analyze the expression of microRNA-139-5p.

Notch pathway deactivation mediated by F-box/WD repeat domain-containing 7 ameliorates hydrogen peroxide-induced apoptosis in rat periodontal ligament stem cells.

Objective: To investigate the protective role of F-box/WD repeat domain-containing 7 in rat periodontal ligament stem cells under oxidative stress.

Materials And Methods: The apoptosis of rat periodontal ligament stem cells was induced by exposure to various concentrations of hydrogen peroxide for 24 h, after which cell viability and the cleaved caspase-3 and -9 levels were determined. The levels of proteins in the Notch signaling pathway were determined by western blotting.

[Analysis of factors affecting soft tissue infection after oral and maxillofacial debridement].

Purpose: To explore the factors affecting soft tissue infection after oral and maxillofacial debridement.

Methods: Fifty hundred patients with debridement were enrolled in this study from January 2013 to June 2016. The patients were divided into 2 groups according to soft tissue infection, 18 cases in infection group and 482 cases in non-infection group.

[Effect of functional appliance on upper airway in adolescent patients with skeletal Class II malocclusion].

Purpose: To investigate the effect of functional appliance on upper airway in adolescent patients with skeletal Class II malocclusion based on cone-beam CT (CBCT).

Methods: Thirty adolescent patients (male:female=1:1) with skeletal Class II malocclusion and their 30 counterparts with skeletal Class I malocclusion were selected. Skeletal Class II malocclusion patients were treated with Activator for 12 months on average, meanwhile skeletal Class I malocclusion patients were treated with fixed appliance without extraction.

Stromal cell-derived factor 1 protects human periodontal ligament stem cells against hydrogen peroxide-induced apoptosis.

Periodontal ligament stem cells (PDLSCs) are considered a promising cell source for dental tissue regeneration. Stromal cell-derived factor 1 [SDF‑1, also known as chemokine (C‑X‑C motif) ligand 12] is regarded as a critical cytokine involved in stem/progenitor cell chemotaxis and homing during tissue regeneration. The present study described a previously unsuspected role for SDF‑1 in the protection of PDLSCs against oxidative stress‑induced apoptosis.

[Inter-relationship between mandibular rotation center and maxillary Le Fort I impaction osteotomies].

Purpose: The purpose of the present investigation was to locate the instantaneous rotation center of the mandible during maxillary surgical impaction, and explore the relationship between automatic rotation center of the mandible and maxillary elevation amount, the length of the mandible and mandibular plane angle.

Methods: Twenty-five patients who underwent maxillary Le Fort I impaction without concomitant major mandibular ramus split osteotomies were included. The preoperative and postoperative lateral cephalograms were used to evaluate the surgical changes and locate the mandibular autorotation center with Reuleaux method.

Assessment of dental age of children aged 3.5 to 16.9 years using Demirjian's method: a meta-analysis based on 26 studies.

Background: A method for assessing dental maturity in different populations was first developed in 1973 by Demirjian and has been widely used and accepted since then. While the accuracy for evaluating dental age using Demirjian's method compared to children's chronological age has been extensively studied in recent years, the results currently available remain controversial and ambiguous.

Methods: A literature search of PubMed, Embase, Web of Science, CNKI and CBM databases was conducted to identify all eligible studies published before July 12th, 2013.

[Research on periodontal changes on the compression side during rapid tooth movement into newly distracted bone].

Purpose: To investigate periodontal remodeling mechanism on the compression side during early tooth movement into newly distracted bone.

Methods: Ten male Beagle dogs were selected. Distraction osteogenesis was performed on randomized side as experimental group, while the fourth premolars were extracted on the other side as control group.

[Establishment of a dog model of orthodontic tooth moving into newly distracted bone].

Purpose: This study was to establish an animal model of tooth moving into newly distracted bone after mandibular distraction osteogenesis in Beagle dog.

Methods: Eight Beagle dogs were selected in this study four dogs (experiment group) underwent 10 mm of bilateral mandibular distraction osteogenesis. After 0-week consolidation periods, the bilateral third premolars were moved distally into the regenerated bone with 150g orthodontic force for 8 weeks.

Reconstruction of partial maxillary defect with intraoral distraction osteogenesis assisted by miniscrew implant anchorages.

Objective: The paper reports a custom-made trifocal transport distractor assisted by miniscrew implant anchorages (MIAs) used to reconstruct maxillary defects and evaluates the clinical results of function and esthetics.

Study Design: Eight patients aged 19-43 years who suffered regional maxillary defects were involved. Each one underwent segmental bone excision of the maxilla and distraction osteogenesis (DO) in the defect region by a custom-made interoral 3-dimensional distractor which was activated by orthodontic elastic force assisted by MIAs at the rate of View Article and Find Full Text PDF

[Cephalometric analysis of implant anchorage-assisted retraction of anterior teeth].

Purpose: The purpose of this study is to compare the different effects of alveolar bone remolding due to retraction of anterior teeth by two types of anchorage mini-screw implant or regular maximum anchorage.

Methods: The sample comprised 26 orthodontic patients with upper dental alveolar bone protrusion and mild crowding. The treatment plan was to remove the four first bicuspids.

[Clinical evaluation of implant anchorage for molar intrusion: report of the short-term results].

Purpose: The purpose of this study is to evaluate the efficiency and security of self-drilling mini-screw implant anchorage for molar intrusion, to achieve the right position of the mini-screw implant.

Methods: Ten patients with overerupted maxillary molars were selected, aging from 25 to 53 years old, the average age was 33 years old. There were 2 men and 8 women.

[Research advances on distraction osteogenesis combined with rapid orthodontic movement].

The principle of distraction osteogenesis can be applied to the correction of facial skeletal deformities.The orthodontists pay more attention to the tooth moving into the new generated bone to relieve the crowding.This paper reviewed the clinical application and histological feature of the distraction osteogenesis,the opportunity and the force magnitude of tooth movement into the new generated bone.