Publications by authors named "Xinshu Xu"
The association between ambient air pollution and colorectal cancer: a Mendelian randomization study.
Int J Environ Health Res
February 2025
Article Synopsis
- Epidemiological studies suggest a link between air pollution and colorectal cancer (CRC), but the genetic aspect remains unclear.
- A study using UK biobank data found a significant association between long-term nitrogen oxide (NO) exposure and increased CRC risk, with an odds ratio of 1.02.
- No significant links were found for other pollutants, emphasizing the need to address NO pollution to reduce CRC risk.
Article Synopsis
- * Immune checkpoint inhibitors (ICIs) show promise as a treatment for MSI-H CRC, demonstrating better response rates than traditional chemotherapies, necessitating a thorough analysis of their effectiveness and safety.
- * The proposed study will systematically review clinical trials comparing ICIs to standard treatments for MSI-H CRC, focusing on outcomes like survival rates and adverse effects while assessing the quality of the studies involved.
Objective: To find the mutation of disease-causing genes of sudden unexplained death syndrome (SUDS) in the young by whole exome sequencing in one case.
Methods: One SUDS case was found no obvious fatal pathological changes after conventional autopsy and pathological examination. The whole exome sequencing was performed with the Ion Torrent PGM™ System with hg19 as reference sequence for sequencing data.
Objective: To explore the postmortem changes of cornea thickness measured by ultrasonic pachymetry.
Methods: Eleven rabbits were randomly divided into two groups: one group with intact corneal epithelium and another group without intact corneal epithelium. In the later group, the corneal epithelium of the rabbit was scraped using mechanical elimination method.