Publications by authors named "Xinru Yang"

By analyzing facial features to perform expression recognition and health monitoring, facial perception plays a pivotal role in noninvasive, real-time disease diagnosis and prevention. Current perception routes are limited by structural complexity and the necessity of a power supply, making timely and accurate monitoring difficult. Herein, a self-powered poly(vinyl alcohol)-gellan gum-glycerol thermogalvanic gel patch enabling facial perception is developed for monitoring emotions and atypical pathological states.

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Ionogel polymer electrolyte (IPE), incorporating ionic liquid (IL) within a polymer matrix, presents a promising avenue for safe quasi-solid-state lithium metal batteries. However, sluggish Li kinetics, resulting from the formation of [Li(anion)] clusters and the occupation of Li transport sites by organic cations, limit their practical applications. In this study, we have developed zwitterionic bottlebrush polymers-based IPE with promoted Li conduction by employing poly(sulfobetaine methacrylate)-grafted poly(vinylidene fluoride-co-chlorotrifluoroethylene) (PVC-g-PSBMA) bottlebrushes as matrices of IL.

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Article Synopsis
  • Current collectors are crucial for enhancing electrochemical performance in zinc-based flow batteries, but traditional materials like 3D carbon felts are not effective for zinc plating.
  • A new current collector using gravity-induced gradient copper nanoparticles (CF-G-Cu NPs) has been developed to improve zinc deposition and reduce unwanted side reactions by optimizing conductivity and promoting better zinc nucleation.
  • The CF-G-Cu NPs electrodes show impressive performance, achieving a high capacity and longevity, with low efficiency decay, thereby presenting a promising approach for advancing zinc-based flow battery technology.
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With the growing demand for healthy and sustainable food, blue food proteins have emerged as an important way to address resource-intensive production and environmental concerns. This paper systematically reviewed the extraction technologies, properties and bioactivities of blue food proteins and explored their wide range of applications. The novel extraction technologies not only improve the extraction efficiency of the proteins, shorten the production time and have environmental advantages, but also enhance the protein properties and facilitate subsequent applications.

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Background: Bone-destructive diseases including rheumatoid arthritis (RA), osteoporosis, and bone metastases, are increasingly prevalent and worrisome due to the over-activated of osteoclasts. Chongrenside D (CGD) is a furostanol saponin extracted from Smilax china L, which has been demonstrated to have anti-inflammatory properties in our previous research. However, its effect on rheumatoid arthritis, especially on osteoclast differentiation and bone destruction has not yet been investigated.

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Organic materials are promising candidates for the electrodes of aqueous zinc-ion batteries due to their nonmetallic nature, environmental friendliness, and cost-effectiveness. However, they often suffer from significant dissolution during the charge-discharge process, which poses a major hurdle to their practical applications. Inspired by membrane-less organelles in cells, a simple and versatile strategy is proposed-constructing a Janus catholyte/cathode structured electrode based on liquid-liquid phase separation, in which redox-active organic molecules are confined in the liquid state within the activated carbon, thereby eliminating the volume effect and preventing their diffusion into the electrolyte.

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Article Synopsis
  • Sepsis is a serious condition resulting from an unchecked immune response to infection, leading to organ dysfunction and high mortality rates; current treatments mainly offer supportive care without targeting the underlying causes.
  • Sirtuins (SIRTs), a family of enzymes involved in various biological processes, show promise in addressing inflammation and other pathways affected by sepsis.
  • This review consolidates existing research on SIRTs and their mechanisms in sepsis, focusing on the potential of SIRT-related drugs as therapeutic targets for improved treatment outcomes.
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Background: As an important platform for researchers to present their academic findings, medical journals have a close relationship between their evaluation orientation and the value orientation of their published research results. However, the differences between the academic impact and level of disruptive innovation of medical journals have not been examined by any study yet.

Objective: This study aims to compare the relationships and differences between the academic impact, disruptive innovation levels, and peer review results of medical journals and published research papers.

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Article Synopsis
  • - The study examines how fatigue in nasopharyngeal carcinoma (NPC) patients is related to weekly changes in body composition during radiotherapy, using assessments at multiple time points (T0-T7).
  • - Results show that fatigue peaked around the fifth week, with significant body composition changes starting as early as the second week; weight and other body composition measures were positively linked to fatigue levels.
  • - The findings suggest that monitoring weight and body composition loss can help independently assess fatigue development in NPC patients, particularly in those with specific demographic and treatment-related factors.
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Sensing of both temperature and strain is crucial for various diagnostic and therapeutic purposes. Here, we present a novel hydrogel-based electronic skin (e-skin) capable of dual-mode sensing of temperature and strain. The thermocouple ion selected for this study is the iodine/triiodide (I/I) redox couple, which is a common component in everyday disinfectants.

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Article Synopsis
  • * Conducted from January 2021 to June 2022, the study followed 105 NPC patients weekly, assessing fatigue through the Piper Fatigue Scale and nutritional status using the Patient-Generated Subjective Global Assessment (PG-SGA) alongside other metrics.
  • * Results indicated that fatigue peaked in the fifth week of treatment, with higher PG-SGA scores correlating weakly with increased fatigue levels; however, PG-SGA emerged as a better predictor for future fatigue than body composition metrics when adjusted for anxiety
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This study uses a data-driven approach to mine the distribution of personality traits among Chinese people in the Chinese social context. Based on the hypothesis of personality lexicology, word embedding technology was employed in machine learning to mine personality vocabulary from Tencent's word embedding database. More than 10,000 Chinese personality descriptors were extracted and analyzed using Gaussian Mixture Model Cluster and Hierarchical clustering analysis.

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Asperosaponin VI (ASA VI) is a bioactive triterpenoid saponin extracted from Diptychus roots, of Diptyl, and has previously shown protective functions in rheumatoid arthritis and sepsis. This study investigates the effects and molecular mechanisms of ASA VI on skeletal muscle regeneration in a cardiotoxin (CTX)-induced skeletal muscle injury mouse model. Mice were subjected to CTX-induced injury in the tibialis anterior and C2C12 myotubes were treated with CTX.

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Objective: Drug-resistant tuberculosis (DR-TB) in children seriously threatens TB control. Information on the epidemiology and characteristics of DR-TB in children in China is limited. We studied data in Shenyang Tenth People's Hospital to understand the DR-TB epidemiology in children in Shenyang.

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Dye pollution is becoming increasingly severe. This study used the Schiff base reaction to synthesize a polyaromatic ring covalent organic polymer material with amide bonds and high electronegativity named SLEL-9 to adsorb Methylene Blue (MB) and Rhodamine B (RhB). SLEL-9 was characterized by Fourier transform infra-red spectra, X-ray photoelectron spectra, Brunauer-Emmett-Teller (BET), zeta potential analysis, and other techniques.

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Article Synopsis
  • - This study investigates the role of MYO6 in the differentiation of osteoclasts and its contribution to joint damage in a mouse model of rheumatoid arthritis.
  • - Using various methods, including micro-CT imaging and enzyme assays, researchers found that mice lacking MYO6 showed less arthritis symptoms and reduced bone damage, linked to inhibited osteoclast development.
  • - MYO6 was identified as crucial for podosome organization and endosome transport in osteoclasts, affecting their function and potentially impacting arthritis progression.
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Background: Asperosaponin VI (AVI) is a natural triterpenoid saponin isolated from Dipsacus asper Wall with documented anti-inflammatory and bone protective effects. Our previous work reported that AVI protects the liver of septic mice from acute inflammatory damage. In this paper, we further explored the protective effect and the potential mechanisms of AVI in alcoholic fatty liver disease (AFLD).

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Chemical constituents of ethanol extract of Pulsatillae Radix were investigated. The n-butanol fraction of ethanol extract of Pulsatillae Radix was isolated and purified by macroporous resin and silica gel column chromatography and semi-preparative high performance liquid chromatography. The triterpenoid glycosides were identified by multiple spectral methods.

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Science, Technology, Engineering, and Math (STEM) education emphasizes solving problems in authentic contexts and developing 21st-century skills. It also helps to cultivate individuals possessing scientific curiosity and innovative abilities. These capacities align with China's core literacy training.

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The morphological diversity of leaf margin shapes is an identifying characteristic of many plant species. In our previous work, BoALG10 (α-1,2 glycosyltransferase) was predicted to be a key regulator of leaf margin shape in ornamental kale ( var. ).

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Molasses have a prominent effect on the bioremediation of Cr(VI) contaminated groundwater. However, its reaction mechanism is not detailed. In this paper, the removal of Cr(VI) with different carbon sources was compared to explore the effect and mechanism of the molasses.

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The COVID-19 outbreak brought online learning to the forefront of education. Scholars have conducted many studies on online learning during the pandemic, but only a few have performed quantitative comparative analyses of students' online learning behavior before and after the outbreak. We collected review data from China's massive open online course platform called icourse.

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Quinone compounds, which are capable of accommodating proton (H ), are emerging electrodes in aqueous batteries. However, the storage mechanism of proton in quinone compounds is less known and the energy/power density of quinone-based proton battery is still limited. Here we design a series of quinone anodes and study their electrochemical properties in acidic electrolyte, in which tetramethylquinone (TMBQ) delivers a high capacity of 300 mAh g with an extremely low polarization of 20 mV at 1 C, and maintains over 50 % theoretical capacity in less than 16 seconds.

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We developed bacterial ghosts (BGs) as vehicles for delivering DNA vaccines and analyzed their effects on immune responses. Uptake of the plasmids encoding the enhanced green fluorescent protein (pCI-EGFP) and BGs loaded with pCI-EGFP by macrophages was investigated using fluorescence microscopy and flow cytometry. The results showed that pCI-EGFP-loaded BGs were efficiently taken up by macrophages.

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