Publications by authors named "Xinru Huang"

Objective: This study aimed to evaluate the effectiveness of school environmental factors in promoting adolescents' physical activity.

Methods: A systematic search of five databases (PubMed, Embase, Web of Science, EBSCO, and Cochrane Library) was conducted from the earliest available records up to September 2023. Meta-analyses were performed for each school environmental factor, provided that at least two studies reported on the association between that factor and adolescents' physical activity.

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Fucoidan, a sulfated polysaccharide rich in fucose, is derived from brown algae and marine invertebrates. Multiple bioactivities have been shown with fucoidan, while growing attraction has emerged in its low-molecular-weight (Mw) hydrolysates. Here, the anti-inflammatory effect of fucoidan, low-Mw acidolyzed fucoidan (LMAF, <1.

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A facile and highly specific optical sensing strategy is established for glyphosate (GLYP) detection using structure-switching signaling aptamers (F-SSSAs) with fluorescence signal reporting functionality. The strategy involves two domains: the FITC-labeled signal transduction domain for fluorescence signal reporting, while the functional domain (specific structure-switching aptamers) controls the target recognition. Graphene oxide (GO) works as a robust F-SSSAs quencher in the absence of GLYP.

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Mechanoluminescence (ML) materials have attracted much attention because of their mechano-optical conversion characteristics, which have shown broad application prospects in stress sensing and anti-counterfeiting technology in the past few decades. However, elastico-ML has not been demonstrated at the near-ultraviolet (NUV) range. In this study, a novel NUV elastico-ML material (Ca, Sr)MgAlSiO:Ce (CSMASOC) with a melilite-type structure is successfully developed.

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The impact of the digital economy on the healthcare sector is becoming increasingly profound. This article focuses on the relationship between the development of China's digital economy and medical and health services supply. Based on panel data from 30 provinces in China from 2012 to 2021, the CRITIC weight method was applied to measure the supply capacity of medical and health services and the level of digital economy development, and the kernel density estimation method and Dagum Gini coefficient method was used to characterize the evolutionary trends and regional differences.

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Article Synopsis
  • * A new digital microfluidic system has been created to efficiently screen multiple drugs using these tumor cells, achieving high throughput with a compact design.
  • * Validations in mice and patient liver cancer samples indicate that the system can effectively identify suitable drugs for individual tumors, supporting its potential to improve precision medicine in cancer treatment.
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Revealing the mechanisms that influence transcription factor binding specificity is the key to understanding gene regulation. In previous studies, DNA double helix structure and one-hot embedding have been used successfully to design computational methods for predicting transcription factor binding sites (TFBSs). However, DNA sequence as a kind of biological language, the method of word embedding representation in natural language processing, has not been considered properly in TFBS prediction models.

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Near-infrared mechanoluminescence is a phenomenon that produces high penetrating near-infrared light under external stimulation. Near-infrared light coincides with the biological window, lower optical loss, and the fact that the mechanoluminescence material is a medium that converts mechanical energy into light energy. The near-infrared mechanoluminescence material has potential application prospects in the fields of biological imaging, medical diagnosis, and monitoring of building materials.

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Elastico-mechanoluminescence technology has shown significant application prospects in stress sensing, artificial skin, remote interaction, and other research areas. Its progress mainly lies in realizing stress visualization and 2D or even 3D stress-sensing effects using a passive sensing mode. However, the widespread promotion of mechanoluminescence (ML) technology is hindered by issues such as high stress or strain thresholds and a single sensing mode based on luminous intensity.

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  • Fucoidan is a substance found in food and medicine that has helpful effects on health, especially when it's broken down into smaller parts.
  • In a study, different types of fucoidan were tested using human poop samples to see how they affect good and bad bacteria in the gut.
  • The research found that low-molecular weight fucoidan helped produce more beneficial short-chain fatty acids and increased good bacteria like Bifidobacterium, showing that it could be useful for health.
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Background: With the increasing prevalence of obesity, weight loss has become a critical issue in China. Self-managed weight loss through a mobile health (mHealth) app may be a prospective method. However, its practicability in different economic regions of China is unknown.

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Chain adsorption to nanofiller interfaces creating bound layers has become central to understanding property changes in polymer nanocomposites. We determine the impact different kinds of adsorbed layers can have on the local glass transition temperature Tg of polymer matrices in a model film system using a localized fluorescence method. This work compares the adsorption and desorption of adsorbed layers grown in solution with the solution washing characteristics of adsorbed layers formed in the melt, leveraging knowledge about polymer adsorption in solution to infer the structure of adsorbed layers formed in the melt.

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Obesity is a complex metabolic disorder, manifesting as excessive accumulation of body fat. Ten-Eleven Translocation-2 (TET2) has garnered significant attention in the context of obesity due to its crucial role in epigenetic regulation and metabolic homeostasis. In this study, we aimed to investigate the effect of endothelial TET2 on obesity and explore the potential mechanism.

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Both soluble dietary fiber (SDF) and insoluble dietary fiber (IDF) play pivotal roles in maintaining gut microbiota homeostasis; whether the effects of the different ratios of IDF and SDF are consistent remains unclear. Consequently, we selected SDFs and IDFs from six representative foods (apple, celery, kale, black fungus, oats, and soybeans) and formulated nine dietary fiber recipes composed of IDF and SDF with a ratio from 1 : 9 to 9 : 1 (NDFR) to compare their impact on microbial effects with healthy mice. We discovered that NDFR treatment decreased the abundance of Proteobacteria and the ratio of Firmicutes/Bacteroidetes at the phylum level.

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This review summarized how TFs function independently or in response to environmental factors to regulate terpenoid biosynthesis via fine-tuning the expression of rate-limiting enzymes. Terpenoids are derived from various species and sources. They are essential for interacting with the environment and defense mechanisms, such as antimicrobial, antifungal, antiviral, and antiparasitic properties.

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Background: Mental health problems have become prominent among college students. The purpose of this study was to to explore the influence of yoga course on female college students' mental health.

Methods: Three hundred fifty-four female college students enrolled in Anhui University of Traditional Chinese Medicine in 2020 or 2021 were selected and divided into three groups according to whether they took PE courses and the content of PE courses: No physical education group (control group) (N.

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Arbuscular mycorrhizal (AM) fungi can form mutualistic endosymbiosis with > 70% of land plants for obtaining fatty acids and sugars, in return, AM fungi promote plant nutrients and water acquisition to enhance plant fitness. However, how AM fungi orchestrate its own signaling components in response to drought stress remains elusive. Here, we identify a transcription factor containing C2H2 zinc finger domains, RiMsn2 from Rhizophagus irregularis.

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Article Synopsis
  • Diabetes has a significant economic burden on individuals and families, and managing blood glucose through diet is vital.
  • The study investigated the effects of different polysaccharides (BXG, BKG, BAG) on biscuits, focusing on their digestibility and prebiotic benefits.
  • Results indicated that biscuits with BAG had the lowest glycemic index and positively influenced gut health by promoting beneficial bacteria and fatty acid production during fermentation.
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Ginsenosides are a promising group of secondary metabolites for developing anti-inflammatory agents. In this study, Michael acceptor was fused into the aglycone A-ring of protopanoxadiol (PPD)-type ginsenosides (MAAG), the main pharmacophore of ginseng, and its liver metabolites to produce novel derivatives and assess their anti-inflammatory activity in vitro. The structure-activity relationship of MAAG derivatives was assessed based on their NO-inhibition activities.

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Article Synopsis
  • - TET2 is crucial for angiogenesis and recovery in ischemic diseases, but its specific role in these processes has not been clearly defined until now.
  • - In experiments, reducing TET2 levels worsened endothelial cell function under low oxygen, while increasing TET2 improved it, indicating its importance for blood flow recovery and capillary density in models of ischemia.
  • - The study found that TET2 interacts with the STAT3 signaling pathway, affecting the expression of genes that are essential for angiogenesis, providing insight into potential therapeutic targets for treating ischemic conditions.
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Background: Since 2020, longer stay-at-home time in response to the coronavirus disease 2019 (COVID-19) pandemic has changed the weight-related behaviors of Chinese population.

Objectives: To explore the demographic and basic characteristics of body fat scale users and to investigate the changes in obesity-related body composition of overweight and obese users during COVID-19. Further, we analyzed the factors associated with successful weight loss and improved body composition changes in overweight and obese people.

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Nutrient imbalance (i.e., deficiency and toxicity) of microelements is an outstanding environmental issue that influences each aspect of ecosystems.

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family genes play crucial roles in plant growth, development, and abiotic stress responses. The objective of this study was to identify and characterize the genes in perennial ryegrass ( L.).

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Suppression of the chlorophyll a (Chl a) Mg-dechelatase gene, SGR/NYE1, blocks the degradation of Chl a, resulting in a 'stay-green' trait. In this study, we investigated the effect of Chl a catabolism on plant heat-induced leaf senescence in perennial ryegrass (Lolium perenne L.).

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Synopsis of recent research by authors named "Xinru Huang"

  • - Xinru Huang's recent research is primarily focused on the intersection of digital technology and healthcare, notably analyzing the influence of China's digital economy on medical service supply and exploring innovative methods for personalized cancer treatment through digital microfluidics.
  • - Additionally, Huang's studies delve into the molecular biology domain, investigating the roles of transcription factors in gene regulation, particularly within the context of plant biology and stress responses, as well as mechanisms influencing metabolic processes related to obesity and inflammation.
  • - The findings highlight the multifaceted nature of Huang's work, contributing valuable insights into healthcare, biotechnology, and environmental interactions, thereby addressing pressing health concerns while employing advanced technological methodologies.