Publications by authors named "Xinru Han"

Introduction: The co-development of public-private hospitals in China's healthcare system significantly influences the system's service utilisation, but the public-private hospital interaction is poorly understood. Bridging this knowledge gap is crucial for informed policy-making and promoting a more balanced healthcare system. This study measures China's public-private hospital co-development and the impact of provincial and regional economic development levels on public-private hospital co-development.

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  • This study investigates Jinbei oral liquid (JBOL) for treating idiopathic pulmonary fibrosis (IPF) and aims to understand its mechanisms by examining target proteins and active components.* -
  • Using bioinformatics techniques like network pharmacology and molecular docking, researchers identified 122 targets and 34 compounds, highlighting kaempferol, apigenin, and baicalein as significant.* -
  • Key interactions were established between active molecules and target proteins, revealing that pathways such as AGE-RAGE, EGFR, and PI3K-Akt play critical roles in JBOL's effect against IPF.*
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This study employs panel data and a dynamic Almost Ideal Demand System (AIDS) model to investigate the habit formation effect of food consumption among Chinese rural residents and its consequential impact on nutritional intake. The dataset, spanning from 2012 to 2018, encompasses nine provinces in China and involves 5390 rural households. The findings reveal that, excluding beef, mutton, and poultry, there are significant habit formation effect on the consumption of food categories, notably grains, vegetables, and edible oils.

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L-arginine, as an essential substance of the immune system, plays a vital role in innate immunity. MiR155, a multi-functional microRNA, has gained importance as a regulator of homeostasis in immune cells. However, the immunoregulatory mechanism between L-arginine and miR155 in bacterial infections is unknown.

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  • China has introduced Leading Areas for Agricultural Green Development (LAGD) to tackle pollution from livestock farming while ensuring industry growth, but it's unclear if these policies effectively balance emission reduction and stable development.
  • A study of 165 LAGDs from 2010 to 2019 found initial emission increases followed by decreases, with cattle generating over 40% of fecal emissions and pigs over 20%, while reductions in emissions post-2014 were largely linked to decreased pig-related pollutants.
  • The decoupling of emission reduction from output value fluctuated during the study period, highlighting the importance of production efficiency and economic development as influencing factors, ultimately providing insights for future sustainable agricultural policies.
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Nonsyndromic biliary atresia (BA) is a rare polygenic disease, with autoimmunity, virus infection and inflammation thought to play roles in its pathogenesis. We conducted a genome-wide association study in 336 nonsyndromic BA infants and 8900 controls. Our results validated the association of rs17095355 in with BA risk (odds ratio (OR) = 1.

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China is facing a rapidly aging population, and the proportion of the working-age population (WAP) is showing a decreasing trend. In this study, we use a two-stage budgeting quadratic almost-ideal demand system framework to estimate the distribution of food demand elasticity under different proportions of the WAP in rural China. The results show that the income elasticities of rural residents' demand for fruits and vegetables, animal products, oils and fats, and grains were 0.

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China is undergoing a rapid dietary transition as well as a changing income distribution. In this paper, we examine the impacts of income heterogeneity on the prediction of food consumption using a dataset that covered 22,210 urban households in China's 6 provinces. The two-stage Exact Affine Stone Index Implicit Marshallian Demand System (EASI demand system) model, which deals with the problem of censoring and endogeneity, is applied to estimate demand elasticity across income strata.

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The COVID-19 pandemic introduced risks and challenges to global food and nutrition security. In this paper, we examine the impact of the COVID-19 pandemic on the nutritional intake of China’s rural residents using panel data and a fixed effects model. The data were collected in 2019 and 2020 and covered nine provinces and 2631 households in rural China.

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Hemophagocytic lymphohistiocytosis (HLH) is a rare but life-threatening clinical syndrome in children, and the knowledge of it is still limited. Two hundred twenty-seven children with HLH in our hospital were retrospectively analyzed from January 2001 to December 2018. The age of the patients on admission ranged from 1 day to 14 years old.

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In order to deepen the understanding of the impact of major public health emergencies on the oil market and to enhance the risk response capability, this study analyzed the logical relationship between major public health emergencies and international oil price changes, identified the change points, and calculated the probability of abrupt changes to international oil prices. Based on monthly data during six major public health emergencies from 2009 to 2020, this study built a product partition model. The results show that only the influenza A (H1N1) and COVID-19 pandemics were significant reasons for abrupt changes in international oil prices.

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Unlabelled: Maize is a major component of China's cereal production. It is also one of the main feedstocks for China's bioethanol production. To ensure food security, there is flexibility in China's ethanol policy.

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Cancer is a major cause of death in the world. Chemotherapy can extend the life of cancer patients to some extent, but the quality of life is reduced. Therefore, the quest for more efficient and less toxic medication strategies is still at the forefront of current research.

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Over the past 4 decades, China has experienced a nutritional transition and has developed the largest population of internet users. In this study, we evaluated the impacts of internet access on the nutritional intake in Chinese rural residents. An IV-Probit-based propensity score matching method was used to determine the impact of internet access on nutritional intake.

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Obstructive sleep apnea hypopnea syndrome (OSAHS) is associated with multiple system diseases. Neurocognitive dysfunction resulting from central nervous system complications has been reported, especially in children with OSAHS. Chronic intermittent hypoxia is accepted to be the major pathophysiological mechanism of OSAHS.

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The use of wastewater for rearing domestic animals is a common phenomenon in most of the developing countries like Pakistan that face a serious shortage of freshwater resources. However, most of the literature has only focused on the indirect effects of wastewater use on animal health or productivity, and literature on the direct effects of wastewater use is rare. Therefore, this study aims to investigate the direct and indirect effects of wastewater usage on the prevalence of animal diseases and animal health in Pakistan.

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The climate change impacts on maize yields are quantified in this paper using statistical models with panel data from 3731 farmers' observations across nine sample villages in Hebei Province of China. The marginal impacts of climate change and the simulated impacts on maize yields based on scenarios of Representative Concentration Pathways 2.6, 4.

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