GPR55 activation improves anxiety- and depression-like behaviors of mice during methamphetamine withdrawal.

Methamphetamine is a potent and highly addictive neurotoxic psychostimulant that triggers a spectrum of adverse emotional responses during withdrawal. G-protein coupled receptor 55 (GPR55), a novel endocannabinoid receptor, is closely associated with mood regulation. Herein, we developed a murine model of methamphetamine-induced anxiety- and depressive-like behavior during abstinence which showed a decreased GPR55 expression in the hippocampus.

Evaluation of the toxicity of clozapine on the freshwater diatom Navicula sp. using the FTIR spectroscopy.

Clozapine is an often prescribed neuroactive pharmaceutical and frequently detected in the aquatic environments. However, its toxicity on low trophic level species (i.e.

Integrated physiological, biochemical, and transcriptomic analysis of thallium toxicity in zebrafish (Danio rerio) larvae.

Although several studies have evaluated the effects of Thallium (Tl) in adult species of fish, the developmental toxicity of Tl has not been previously explored. In this study, zebrafish embryos (<4 h post fertilization (hpf)) were exposed to Tl at concentrations from 0.8 to 400 μg L for 7 d.

Altered life history traits and transcripts of molting- and reproduction-related genes by cadmium in Daphnia magna.

Cadmium (Cd) is a non-essential element and can be toxic to aquatic organisms at low concentrations. Despite its well-known toxicity to Daphnia magna, the effects of Cd on physiological parameters (heart rate and thoracic limb activity) and molting- and reproduction-related genes are relatively understudied. In this study, D.

Dietary Seleno-l-Methionine Causes Alterations in Neurotransmitters, Ultrastructure of the Brain, and Behaviors in Zebrafish ().

Elevated concentrations of dietary selenium (Se) cause abnormalities and extirpation of fish inhabiting in Se-contaminated environments. However, its effect on fish behavior and the underlying mechanisms remain largely unknown. In this study, two-month-old zebrafish () was fed seleno-l-methionine (Se-Met) at environmentally relevant concentrations (i.

[Comparative study on main economic characters of different populations of Pinellia ternata in China].

Objective: To analyze the content of guanosine, total alkaloid and individual yield of Pinellia ternata from different populations in China and evaluate its quality.

Method: Reversed-phase high-performance liquid chromatography (HPLC) was used to determine the content of guanosine. The content of alkaloid was determined by ultra violet spectrophometry.

[Preliminary study on N, P, K fertilizer to control of root rot of Bupleurum chinense].

The application of N and K fertillizer could improve the sensibility of Bupleurvum chinense DC. to Root Rot, while large application of P fertilizer could decrase the sensibility. The fertilizer measure which could obtain highest yield but could not increase its disease resistense.

[Preliminary study on the characteristics of Bupleurum chinense in nutrition uptake].

It was studied that the characteristics of Bupleurum chinense DC. in nutrition uptake based on potted and field experiment to provide a properly fertilizer application measure. The result showed that the absorption amounts of N, P and K were in the order of K > N > P under field condition.

[The growth of Salvia miltiorrhiza seedling and root system following transplantation].

Objective: To study the relationship between plant growth and accumulation of active ingredients in Salvia miltiorrhiza.

Method: Transplants of S. miltiorrhiza were sampled at 20 day intervals.

[Study on the characteristic of assimilating nitrogenous phosphorous fertilizer and the accumulation disciplinarian of total tanshinons of Salvia miltiorrhiza].

Objective: To confirm the amount of fertilizer and the ration of fertilizer.

Method: Through the experiment of planting Salvia miltiorrhiza in pot and in field were carried out.

Result: When N:P = 1:1, The production was 1.

[Study on configuration fabric and germinative conditions of Salvia miltiorrhizy seeds].

Objective: To provide theoretic warrant and technical reference for Salvia miltiorrhizr standardization planting, by carrying out various systemic studies such as observation of seeds configuration fabric, idiosyncrasy of water absorption and groping germinating conditions.

Method: In the study of configuration fabric, seeds were observed and taken photos by scanning electronic microscope, and heft method was used for measuring changes of water absorption velocity and dehydration velocity. Seeds germination conditions were probed into under the national test regulations for crop seeds and related prescription from international standards.