Publications by authors named "Xinreng Mo"
Article Synopsis
- The study focuses on a pathogenic fungus that poses significant risks to immunocompromised individuals, aiming to understand how it causes disease by examining fungal gene expression during infection.* -
- Researchers found that the expression of two specific MAPK proteins, Fus3 and Kss1, greatly increases during infection, and deleting both genes simultaneously reduces fungal presence in the host's organs and gut.* -
- The findings suggest that this MAPK signaling pathway is essential for the fungus's ability to persist and exhibit virulence, highlighting its importance in the organism's pathogenic capabilities.*
The pathway of yeasts has long served as a model system for understanding of how regulatory mode of eukaryotic metabolic pathways evolves. While Gal4 mode has been well-characterized in Saccharomycetaceae clade, little is known about the regulation of the pathway in other yeasts. Here, we find that Rep1, a Ndt80-like family transcription factor, serves as a galactose sensor in the commensal-pathogenic fungus .
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