Spider-silk inspired ultrafast alkali-induced molecular aggregation for 3D printing arbitrary tubular hydrogels.

Fabricating tubular hydrogel models with arbitrary structural complexity and controllable diameters using an ultrafast, facile yet universal method is desirable for vascular prototypes yet still a great challenge. Herein, inspired by the denaturing ability of spider silks, a novel strategy to induce complexation applying highly concentrated alkali into a polyvinyl alcohol/ionic liquid (PVA/IL) solution, , alkali-induced molecular aggregation (AMA), is proposed to achieve such purpose. This strategy enables the rapid and facile fabrication of tubular hydrogel architectures with tunable diameters, controllable thicknesses, and excellent mechanical performance with a tensile strength of up to 1.

Differential expression of lymphocyte subpopulations in the peripheral blood of patients with COVID-19: Implications for disease severity and prognosis.

Objective: To investigate the expression patterns and clinical significance of specific lymphocyte subsets in the peripheral blood of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

Methods: Between December 2022 and February 2023, a cohort of 165 patients from the First Affiliated Hospital of Guangzhou University of Chinese Medicine were analyzed. The participants represented various stages of coronavirus infection severity: mild, moderate, severe, and critical.

Hydrophobic Modified Ceramic Aeration Membrane for Effective Treatment of Brine Wastewater.

A novel approach to evaporate brine wastewater using a ceramic aeration membrane was proposed. A high-porosity ceramic membrane was selected as the aeration membrane and was modified with hydrophobic modifiers to avoid undesired surface wetting. The water contact angle of the ceramic aeration membrane reached 130° after hydrophobic modification.

Processing Optimization of Shear Thickening Fluid Assisted Micro-Ultrasonic Machining Method for Hemispherical Mold Based on Integrated CatBoost-GA Model.

Micro-electro-mechanical systems (MEMS) hemispherical resonant gyroscopes are used in a wide range of applications in defense technology, electronics, aerospace, etc. The surface roughness of the silicon micro-hemisphere concave molds (CMs) inside the MEMS hemispherical resonant gyroscope is the main factor affecting the performance of the gyroscope. Therefore, a new method for reducing the surface roughness of the micro-CM needs to be developed.

The unique mean seasonal cycle in the Indian Ocean anchors its various air-sea coupled modes across the basin.

The interannual variability of the sea surface temperature (SST) in the Indian Ocean is complex and characterized by various air-sea coupled modes, which occur around El Niño/La Niña's peak phase (i.e. December-January-February, DJF).

Background-Free Chromatographic Detection of Sepsis Biomarker in Clinical Human Serum through Near-Infrared to Near-Infrared Upconversion Immunolabeling.

Luminescence nanomaterial-based lateral flow assay (LFA) is promising for point-of-care tests. However, the detection sensitivity and accuracy are often affected by the interferences of autofluorescence and photon scattering from nitrocellulose membrane and colored plasma. Here, we describe a near-infrared to near-infrared upconversion nanoparticle (UCNP) immunolabeled LFA for background-free chromatographic detection of sepsis biomarker procalcitonin (PCT) in clinical human plasma.

Effect of Homochirality of Dipeptide to Polymers' Degradation.

As natural polymer materials, proteins are readily biodegradable, interestingly, the synthetic polyamides (PAs) that are based on the same amide bonds (also called peptide bonds in proteins) are barely degradable. Whether did the chirality and configuration of the amino acids play an important role. By using different configuration of amino acids, 4 types of polyamide-imides (PAIs) containing dipeptides of LL, DL, LD, and DD configurations, respectively, were synthesized.

SACE_0012, a TetR-family transcriptional regulator, affects the morphogenesis of Saccharopolyspora erythraea.

Saccharopolyspora erythraea, a mycelium-forming actinomycete, produces a clinically important antibiotic erythromycin. Extensive investigations have provided insights into erythromycin biosynthesis in S. erythraea, but knowledge of its morphogenesis remains limited.