Generational Specific Recruitment of Arsenic- and Antimony-Reducing Microorganisms in Plant Root-Associated Niches for Adapting to Metalloid-Metal Pollution.

The recruitment of microorganisms by plants can enhance their adaptability to environmental stressors, but how root-associated niches recruit specific microorganisms for adapting to metalloid-metal contamination is not well-understood. This study investigated the generational recruitment of microorganisms in different root niches of () under arsenic (As) and antimony (Sb) stress. The was cultivated in As- and Sb-cocontaminated mine soils (MS) and artificial pollution soils (PS) over two generations in controlled conditions.

Sertraline Promotes Health and Longevity in Caenorhabditis elegans.

Introduction: While several antidepressants have been identified as potential geroprotectors, the effect and mechanism of sertraline on healthspan remain to be elucidated. Here, we explored the role of sertraline in the lifespan and healthspan of Caenorhabditis elegans.

Methods: The optimal effect concentration of sertraline was first screened in wild-type N2 worms under heat stress conditions.

Dual-Targeted Graphitic Cascade Nanozymes for Recognition and Treatment of Helicobacter pylori.

Helicobacter pylori (H. pylori) is the major etiological factor of a variety of gastric diseases. However, the treatment of H.

Single-atom-anchored microsweepers for inhibition through dynamically navigated reciprocating locomotion.

Catalytic microsweepers with a single-iron-atom center were designed to search for and inhibit . Under dynamic navigation, the microsweepers displayed a large-range wall-adhering reciprocating motion, which increased the opportunity for interaction between microsweepers and and further inhibited through acid-responsive reactive oxygen species generation.

An Implantable Magnetic Vascular Scaffold for Circulating Tumor Cell Removal In Vivo.

An integrated trapped device (ITD) capable of removal of circulating tumor cells (CTCs) can assuage or even prevent metastasis. However, adhesion repertoires are ordinarily neglected in the design of ITDs, possibly leading to the omission of highly metastatic CTC and treatment failure. Here a vascular-like ITD with adhesive sites and wireless magnetothermal response to remove highly metastatic CTC in vivo is presented.

Sympathetic blockage attenuates fasting-induced hepatic steatosis.

Although the central nervous system coordinates whole-body metabolism, the neural mechanism for hepatic steatosis remains unclear. This study is aimed to explore the neural mechanism of fasting-induced hepatic steatosis. Mice were pretreated with 6-hydroxydopamine to block sympathetic nerve activity before fasting, and to explore the potential effects of chemical sympathectomy on fasting-induced hepatic steatosis and transcriptional changes.

Upregulating Heat Shock Protein 70 via Gastric Nano-Heaters for the Interference of Infection.

Taking inspiration from the mechanism of infection can lead to innovative antibacterial ways to fight antibiotics resistance. Herein, a gastric nano-heater iron-cobalt alloy shielded with graphitic shells (FeCo@G) is developed to interfere with infection under an alternating magnetic field. FeCo@G shows a high and stable specific loss power (SLP = 534.

Charge-Transfer Cocrystal via a Persistent Radical Cation Acceptor for Efficient Solar-Thermal Conversion.

Designing organic charge-transfer (CT) cocrystals for efficient solar-thermal conversion is a long-sought goal but remains challenging. Here we construct a unique CT cocrystal by using a persistent 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation (ABTS ) as the electron acceptor. The strong persistency and electron affinity of ABTS endow a high degree of electron delocalization between ABTS and the 3,3',5,5'-tetramethylbenzidine donor.

Gastric pH Imaging with Hydrogel Capsule Isolated Paramagnetic Metallo-albumin Complexes.

Abnormal gastric pH (pH > 3) has instructive significance for early diagnosis of various diseases, including cancer. However, for low patient compliance, limited penetration depth, high dependence on physiological function or unsafety issue, noninvasive monitoring gastric pH is challenged. Herein, we developed a hydrogel capsule isolated human serum albumin-manganese complex (HSA-Mn) for magnetic resonance imaging (MRI) gastric pH monitoring for the first time.

Rapid identification of dragon blood samples from Daemonorops draco, Dracaena cinnabari and Dracaena cochinchinensis by MALDI-TOF mass spectrometry.

Introduction: Dragon blood is a deep-red plant resin which has been used as folk medicine for more than a thousand years. It can be produced from at least four entirely different plant families: Asparagaceae, Arecaceae, Chamaesyce, and Fabaceae. Current pharmacopeia states that the only "authentic" source of dragon blood is the palm tree, Daemonorops draco.